Feher 2017 Academic Press

Feher J (2017) 2.10 - ATP production II: The TCA cycle and oxidative phosphorylation. Quantitative human physiology (2nd ed) Academic Press, Boston:277-40. https://doi.org/10.1016/B978-0-12-800883-6.00021-5

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Feher Joseph (2017) Academic Press, Boston

Abstract: This chapter begins with pyruvate conversion into acetyl CoA and CO2 by the enzyme pyruvate dehydrogenase. It then describes the combination of acetyl CoA with oxaloacetate to form citric acid. It then follows all of the biochemical transformations that convert citric acid back to oxaloacetate and 2 CO2 molecules, producing NADH and FADH2 and GTP along the way. How NADH and FADH2 lead to the synthesis of ATP is considered in the discussion of the electron transport chain and ATP synthetase. The energetic of the electrochemical potential of hydrogen ions across the inner mitochondrial membrane is discussed.

• Bioblast editor: Gnaiger E

Correction: FADH₂ and Complex II

FADH₂ is shown as the substrate feeding electrons into Complex II (CII). This is wrong and requires correction - for details see Gnaiger (2024).

Gnaiger E (2024) Complex II ambiguities ― FADH₂ in the electron transfer system. J Biol Chem 300:105470. https://doi.org/10.1016/j.jbc.2023.105470 - »Bioblast link«