Gnaiger 2017 MiPschool A1

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Elemental steps towards understanding mitochondrial core energy metabolism: coupling control.

Link: MitoEAGLE

Gnaiger E (2017)

Event: MiPschool Obergurgl 2017

COST Action MitoEAGLE


Bioblast editor: Gnaiger E O2k-Network Lab: AT Innsbruck Gnaiger E


Labels: MiParea: Respiration 



Preparation: Intact cells, Permeabilized cells, Permeabilized tissue, Isolated mitochondria 

Regulation: Coupling efficiency;uncoupling  Coupling state: LEAK, ROUTINE, OXPHOS, ET  Pathway: ROX 

Event: A1, Review  MitoEAGLE 

Affiliations

Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, AT; and Oroboros Instruments, Innsbruck, AT. - erich.gnaiger@oroboros.at

References

  1. Chance B, Williams GR (1955) Respiratory enzymes in oxidative phosphorylation. III. The steady state. J Biol Chem 217:409-27. - »Bioblast link«
  2. Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65:1983-2002. - »Bioblast link«
  3. Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. - »Bioblast link«
  4. Gnaiger E, Méndez G, Hand SC (2000) High phosphorylation efficiency and depression of uncoupled respiration in mitochondria under hypoxia. Proc Natl Acad Sci U S A 97:11080-5. - »Bioblast link«

Support

K-Regio project MitoFit.