Hinkle 1972 J Biol Chem
Hinkle PC, Kim JJ, Racker E (1972) Ion transport and respiratory control in vesicles formed from cytochrome oxidase and phospholipids. J Biol Chem 247:1338-9. |
Β» PMID: 4334497 Open Access; PDF
Hinkle PC, Kim JJ, Racker E (1972) J Biol Chem
Abstract: Vesicles formed from cytochrome oxidase and phospholipids catalyzed the oxidation of reduced cytochrome c in a manner similar to that of intact mitochondria. A respiration-dependent release of protons and uptake of potassium ions were observed in the presence of valinomycin with reduced 1,4-naphthoquinone-2-sulfonate as reductant for cytochrome c. With ascorbate as reductant 3- to 5-fold stimulation of respiration was observed on addition of uncouplers or ionophorous agents. β’ Keywords: Ion transport, Respiratory control, Cytochrome oxidase, Phospholipids, Vesicles
Labels: MiParea: Respiration
Organism: Bovines
Tissue;cell: Heart
Preparation: Isolated mitochondria, SMP
Enzyme: Complex IV;cytochrome c oxidase
Regulation: Ion;substrate transport, Substrate
Coupling state: OXPHOS
Made history