Holloway GP

From Bioblast
Jump to: navigation, search


e-COST MitoEAGLE
e-COST MitoEAGLE countries
MitoGlobal
MitoEAGLE
News and Events         About COST Action MitoEAGLE         Working Groups         MiP/MitoEAGLE Traning School 2019 Coimbra PT         MitoEAGLE Preprint States and rates         Short-Term Scientific Missions         Inclusiveness Target Countries         Management Committee         Members    


MiPsociety
COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


 

Holloway GP


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Name Holloway Graham P, PhD, Assistant Prof.
Institution
Graham Holloway
Dept Human Health and Nutritional Sciences,

University of Guelph, CA

Address 50 Stone Rd., N1G2W1
City Guelph
State/Province Ontario (ON)
Country Canada
Email ghollowa@uoguelph.ca
Weblink
O2k-Network Lab CA Guelph Holloway GP


Labels:



Publications

 PublishedReference
Petrick 2019 Biochem J2019Petrick HL, Holloway GP (2019) High intensity exercise inhibits carnitine palmitoyltransferase-I sensitivity to L-carnitine. Biochem J 476:547-58.
Gnaiger 2019 MitoFit Preprint Arch2019Gnaiger E, Aasander Frostner E, Abdul Karim N, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v4.
Miotto 2019 FASEB J2019Miotto PM, McGlory C, Bahniwal R, Kamal M, Phillips SM, Holloway GP (2019) Supplementation with dietary ω-3 mitigates immobilization-induced reductions in skeletal muscle mitochondrial respiration in young women. FASEB J [Epub ahead of print].
Barbeau 2018 Biochem J2018Barbeau PA, Miotto PM, Holloway GP (2018) Mitochondrial derived reactive oxygen species influence ADP sensitivity, but not CPT-I substrate sensitivity. Biochem J 475:2997-3008.
Monaco 2018 Am J Physiol Regul Integr Comp Physiol2018Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204.
Monaco 2018 Diabetologia2018Monaco CMF, Proudfoot R, Miotto PM, Herbst EAF, MacPherson REK, Holloway GP (2018) α-linolenic acid supplementation prevents exercise-induced improvements in white adipose tissue mitochondrial bioenergetics and whole-body glucose homeostasis in obese Zucker rats. Diabetologia 61:433-44.
Holloway 2018 Cell Rep2018Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC (2018) Age-associated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48.
Baaten 2018 Haematologica2018Baaten CCFMJ, Moenen FCJI, Henskens YMC, Swieringa F, Wetzels RJH, van Oerle R, Heijnen HFG, Ten Cate H, Holloway GP, Beckers EAM, Heemskerk JWM, van der Meijden PEJ (2018) Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica 103:1557-67.
Herbst 2017 Appl Physiol Nutr Metab2017Herbst EAF, George MAJ, Brebner K, Holloway GP, Kane DA (2017) Lactate is oxidized outside of the mitochondrial matrix in rodent brain. Appl Physiol Nutr Metab 43:467-74.
Chorner 2016 Am J Physiol Regul Integr Comp Physiol2016Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP (2016) Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates. Am J Physiol Regul Integr Comp Physiol 311:R1234-42.
Snook 2016 Am J Physiol Regul Integr Comp Physiol2016Snook LA, MacPherson RE, Monaco CM, Frendo-Cumbo S, Castellani L, Peppler WT, Anderson ZG, Buzelle SL, LeBlanc PJ, Holloway GP, Wright DC (2016) Prior exercise training blunts short term highfat diet induced weight gain. Am J Physiol Regul Integr Comp Physiol 311:R315-24.
Herbst 2016 Appl Physiol Nutr Metab2016Herbst EA, Holloway GP (2016) Exercise increases mitochondrial glutamate oxidation in the mouse cerebral cortex. Appl Physiol Nutr Metab 41:799-801.
Miotto 2016 Biochem J2016Miotto PM, Holloway GP (2016) In the absence of phosphate shuttling, exercise reveals the in vivo importance of creatine-independent mitochondrial ADP transport. Biochem J 473:2831-43.
Whitfield 2015 J Physiol2015Whitfield J, Ludzki A, Heigenhauser GJ, Senden JM, Verdijk LB, van Loon LJ, Spriet LL, Holloway GP (2015) Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle. J Physiol 594:421-35.
Herbst 2015 Neuroscience2015Herbst EA, Holloway GP (2015) Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington's disease. Neuroscience 303:515-23.
Herbst 2015 Metabolism2015Herbst EA, Roussakis C, Matravadia S, Holloway GP (2015) Chronic treadmill running does not enhance mitochondrial oxidative capacity in the cortex or striatum. Metabolism 64:1419-25.
Herbst 2015 J Physiol2015Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801.
Paglialunga 2015 Diabetologia2015Paglialunga S, Ludzki A, Root-McCaig J, Holloway GP (2015) In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice. Diabetologia 58:1071-80.
Ludzki 2015 Diabetes2015Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79.
Beaudoin 2014 J Physiol2014Beaudoin MS, Perry CC, Arkell A, Chabowski A, Simpson JA, Wright DC, Holloway GP (2014) In the ZDF rat, impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede the development of diabetic cardiomyopathy are prevented by resveratrol supplementation. J Physiol 592:2519-33.
Herbst 2014 J Physiol2014Herbst EA, Paglialunga S, Gerling C, Whitfield J, Mukai K, Chabowski A, Heigenhauser GJ, Spriet LL, Holloway GP (2014) Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle. J Physiol 592:1341-52.
Lally 2013 PLoS One2013Lally JS, Herbst EA, Matravadia S, Maher AC, Perry CG, Ventura-Clapier R, Holloway GP (2013) Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics. PLoS One 8:e55660.
Smith 2013 J Physiol2013Smith BK, Perry CG, Herbst EA, Ritchie IR, Beaudoin MS, Smith JC, Neufer PD, Wright DC, Holloway GP (2013) Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol. J Physiol 591:6089-101.
Beaudoin 2013 Am J Physiol Regul Integr Comp Physiol2013Beaudoin MS, Snook LA, Arkell AM, Simpson JA, Holloway GP, Wright DC (2013) Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats. Am J Physiol Regul Integr Comp Physiol 305:542-51.
Perry 2012 J Physiol2012Perry CG, Kane DA, Herbst EA, Mukai K, Lark DS, Wright DC, Heigenhauser GJ, Neufer PD, Spriet LL, Holloway GP (2012) Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. J Physiol 590: 5475-5486.
Smith 2012 Biochem J2012Smith BK, Perry CG, Koves TR, Wright DC, Smith JC, Neufer PD, Muoio DM, Holloway GP (2012) Identification of a novel malonyl-CoA IC50 for CPT-I: implications for predicting in vivo fatty acid oxidation rates. Biochem J 448:13-20.
McFarlan 2012 J Biol Chem2012McFarlan JT, Yoshida Y, Jain SS, Han XX, Snook LA, Lally J, Smith BK, Glatz JF, Luiken JJ, Sayer RA, Tupling AR, Chabowski A, Holloway GP, Bonen A (2012) In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance and training-induced adaptation of fatty acid oxidation. J Biol Chem 287:23502-16.
Smith 2011 Biochem J2011Smith BK, Jain SS, Rimbaud S, Dam A, Quadrilatero J, Ventura-Clapier R, Bonen A, Holloway GP (2011) FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation. Biochem J 437:125-34.

Abstracts

 PublishedReference
George 2015 Abstract MiPschool Greenville 20152015Mitochondria do not directly oxidize lactate within the cerebral cortex or hippocampus.
Holloway 2014 Abstract MiP20142014Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions.
Herbst 2014 Abstract MiP20142014Analysis of mitochondrial function in multiple brain regions through in situ permeabilization.
Holloway 2013 Abstract MiP20132013Holloway GP (2013) Tissue specific changes in respiratory substrate kinetics in the ZDF rat and in response to resveratrol supplementation. Mitochondr Physiol Network 18.08.
Holloway 2012 Abstract Bioblast2012Holloway GP (2012) Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics. Mitochondr Physiol Network 17.12.


Participated at