MiPschool Schroecken AT 2008

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MiPschool Schroecken AT 2008

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MiPsociety
MiPsummer 2008. 2nd MiPsummer School. Respiratory Mitochondrial Physiology. 12-18 July 2008, Schröcken, Vorarlberg, Austria. Programme and Abstracts. Mitochondr Physiol Network 13.05: 1-32.

» Bioblast pdf

MiP (2008) Mitochondr Physiol Network

Abstract:

Keywords: MiP

O2k-Network Lab: AT_Innsbruck_Gnaiger E

Programme

view programme here

Location

Location.jpg


MiPsummer 2007, MiP2005, MiP2003 and MiP1999, and many Courses on
High-Resolution Respirometry were held in this secluded alpine village.


Schroecken (Vorarlberg)

is an alpine village, located 150 km West of Innsbruck in the scenic valley of Bregenzerwald, at the slope of the Hochtannberg Pass, most famous for its winter sports facilities in the Arlberg region. Schröcken (left) offers an ideal environment for relaxation and mountaineering in summer and autumn – www.tiscover.at/schroecken.

All together

Participants will stay at Hotel Mohnenfluh, Hotel Tannberg, and guest rooms in walking distance. Meals will be served at Hotel Mohnenfluh (www.tiscover.at/mohnenfluh; Tel +43 5519 2030) for all participants. Your accomodation will be booked through your MiPsummer registration.

Weather, Excursions

Mid July is the top summer season in this area, popular for mountain walking and climbing. The magnificent alpine flora is blooming at this time, and our walks will take us through the most beautiful plant reserve of Vorarlberg.
The culture and history of alpine farming in this area famous for the Alp cheese will be explained (cheese will be tasted) at an excursion to the Alpmuseum, which is unique in Austria.
The evenings at the altitue of 1400 m may be chilly, and the surrounding mountain tops may receive snowfall even during summer. Therefore, one travels to the Alps prepared. For walking tours, good shoes, a raincoat and warm pullover are advantageous. No specific mountaineering equipment is required for excursions. A bathing suit could be recommended for an adventurous swim in the chilly lake Körbersee or Kalbelesee.


Bregenzerwald.jpg


Left: Sergio Papa at the cheese and wine reception, Alpmuseum uf m Tannberg; MiP2003 - www.alpmuseum.at.


The Bregenzerwald
Far, far away from the man-made tourist worlds ... - http://www.bregenzerwald.at/bwt_info_gb.pdf


MiPsummer 2008 Accomodation

Panoramic view of both single rooms in a 2-room appartment.


Participants will be accommodated in Hotel Mohnenfluh, Hotel Hochtannberg, and nearby appartment houses. The Standard Conference Fee includes a single room in a 2-room appartment. Each appartment has a separate shower and bathroom. Student fees imply a more economical sharing of appartments.


Room.jpg
All accomodations are in walking distance of the lecture hall.


The registration fee includes full board. Breakfast will be served at the two hotels and in various appartment houses. Lunch packages will be available at the lecture hall. Dinner will be served in Hotel Mohnenfluh - www.mohnenfluh.at.


Internet access is available at Hotel Mohnenfluh.

MiPsummer 2008 Travel

Schröcken (Vorarlberg, Austria) is located c. 150 km West of Innsbruck.
Transfer by bus from Bregenz to Schröcken, 12. July 2008, 15:30-16:00.


In case of problems with your connections, please call Hotel Mohnenfluh in Schröcken, Tel. +43 (0)5519 2030.
Transfer by bus from Schröcken will be arranged on 18. or 19. July 2008 (departure in Schröcken c. 07:00) to Bregenz.


Travel Connections
  • Zurich airport is the closest international airport to Schröcken. Convenient train connections are available to Bregenz.
  • Munich airport is an international airport with good train connections to Bregenz.
  • MiPsummer Arrivals by train in Bregenz will be picked up by our bus service to Schröcken. For transfer service between Bregenz-Schröcken (see MiPsummer registration), arrivals in Bregenz train station should be not later than 15:30.
  • MiPsummer Departures from Bregenz train station should be not earlier than 11:30.


Car
Schröcken (Vorarlberg, Austria) is located c. 150 km West of Innsbruck. Schröcken is reached from Innsbruck via the Arlberg pass (from St. Anton and St. Christoph), Flexenpass (to Zürs and Lech), and Hochtannberg pass (from Warth to Schröcken). From Zurich (CH) and Bregenz (Vorarlberg, Austria), Schröcken is reached through the valley of Bregenzerwald. From Munich, you may take the road through the scenic Lechtal.



Local Organizers

Erich Gnaiger (Innsbruck, Austria)
Simone Köfler (Innsbruck, Austria) - koefler@oroboros.at


Scientific board


Invitation
The Mitochondrial Physiology Society decided at their general meetings during MiP2007 and MiPsummer 2007 to organize the '2nd MiPsummer School on Mitochondrial Physiology' on 12-18 July 2008 in Schroecken, Austria.
Based on contributions by several members of the MiPadvisory Board, we extend our invitation and ask you for your oppinion, interest, and potential support for this MiPevent. We are confident to continue a successful tradition in line with MiPsummer 2007, by again addressing this activity of the MiPsociety to students (in the widest sense of the word).
We offer the '2nd MiPsummer School' for up to 70 participants, with particular focus on OXPHOS, respiratory chain and mitochondrial respiratory (dys)function in the context of Mitochondrial Physiology. The main topics will evolve according to the specific input by the lecturers and suggestions by participants. A large number of reserach and clinical groups are now entering the field of mitochondrial functional diagnosis, and students require an up-to-date background that can be provided by lecturers who are leaders in the field.
This MiPevent (12.-18. July 2008) preceedes directly the 15th European Bioenergetics Congress in Dublin, Ireland (EBEC 2008).
Full cost, 6 days (accomodation, all meals, registration): € 320.- for students and € 640.- for 'non-students', plus € 55.- for optional MiPtransfer from Bregenz to Schroecken (subject to change, final information will be provided with the registration form).
I thank those colleagues who already agreed to support this MiPsummer School by their valuable contributions to the evolving scientific programme. We welcome further suggestions and contributions, and thank for your cooperation.
Looking forward to seeing you this July
with kind regards,
The Mitochondrial Physiology Society
Erich Gnaiger
Medical University of Innsbruck, Austria
erich.gnaiger@mitophysiology.org


MiPsummer 2008 Registration

Fees cover full board (six nights) including breakfast and all meals, coffee breaks. Transfer between Bregenz-Schröcken and Schröcken-Bregenz will be organized at Euro 55.- round trip.
(1) Student: EURO 320.-
Two-room apartment shared by four student participants. Single room additions are not applicable for student registration fees.
(2) Standard: EURO 640.-
Two-room apartment shared by two participants; for single room +108.- EURO.
Registration closed: MiPsummer2008 (12-18 July 2007): Contact erich.gnaiger@mitophysiology.org.
Abstracts: All abstracts will be reviewed and published on the MiP websitie. For format see MiP2005.
Poster presentations will be selected from the submitted abstracts by the Scientific Advisory Board.
Oral presentations (5+5 min) will be selected from the posters by the Scientific Advisory Board (1) in advance for inclusion into the regular programme, and (2) during the first days, for a general session on one of the last afternoons during the MiPsummer School.

MiPsummer Lecturers and Tutors

Last update: 2008-06-20
The following lecturers and tutors will share their expertise at MiPsummer2008 (list is not yet complete):


International MiPsummer Lecturers
MiPsummer Team of Tutors


MiPsummer 2008 - Topics

Considering the dynamic structure of mitochondria in living cells, it is quite appropriate to develop the programme of MiPsummer 2008 in terms of a dynamic interplay between suggestions by the lecturers and tutors, and interests expressed by all participants. The MiPsummer2008 Program is emerging with the following Topics of Lectures (morning sessions) and Focus Groups (afternoons, some evenings):
  • Respiratory control in isolated mitochondria and permeabilized cells and fibers.
  • Substrates used in mitochondrial oxidative phosphorylation studies and the Q-junction approach.
  • On respiratory control ratios and uncoupling.
  • Mitochondrial and apoptisis: signaling and respiratory function.
  • Mitochondria in signaling pathways: Mechanisms on NO and ROS.
  • Ischemia and reperfusion in the rat heart. Does the mitochondrial damage occur during ischemia?
  • Humans - The effect of developmental age on human skeletal muscle mitochondrial oxidative phosphorylation.
  • Mitochondria, genetics, and obesity in mice - an early project.
  • Isolated mitochondria, permeabilized cells and fibers, or intact cells: Which model is 'best'?
  • Respiration in permeabilized heart fibers versus two populations of isolated mitochondria in the aged rat heart.
  • Permeabiliized muscle fiber and isolated mitochondrial respiration in human skeletal muscle biopsies.
  • Mitochondrial membrane potential: why and how to measure?
  • The TPP+ electrode for measuring mitochondrial membrane potential.
  • Oxygen kinetics and nitric oxide.
  • Resting respiration in 'State 4' – the LEAK state.
  • Metabolism and acid production - aerobic and anaerobic flux.
  • Mitochondrial targeting of protein import.
  • The mitochondrial defect in the aged rat heart and the impact on the increased damage following ischemia in the elderly rats heart - a cardiolipin story.
  • The mitochondrial defect in heart failure in dogs: A story of abnormal oxidative phosphorylation, but with normal ETC complex activities. The answer is in respirasomes or supercomplexes.
  • Liver mitochondrial defects in the aged rat.
  • ...


We ask all speakers and tutors for focus groups, to send us a short list of questions, which will provide for students a guideline on the level of the presentations(balance between introductory and advanced). Posters (or simply 'projects') will be presented (10+5 min or 5+5 min) by participants who submit their abstracts and are selected for presentations.


MiPschool 2008 - Feedback

Notes from roundtable feedback session in Schroecken (July 17, 2008; compiled by Patrick Subarsky and Francesca Scandurra).
Further feedback by Email from participants is welcome.


Lecture Organization

  • separation of abilities (need introduction to field)
  • real introduction to basics for young students
  • need basic introduction
  • first two days to get the basics
  • more background before presentations
  • responses did not flow during the lecture
  • some presentations difficult to understand
  • terminology difficult
  • lecture on coupling and membrane potential was very good
  • included beginner and expert
  • enjoyed Vilma’s style of presentation
  • lecture of C. Hoppel was very good
  • more questions


Topics of Interest

  • don’t have oxygraph, therefore am unfamiliar with method
  • mitochondrial targetting
  • ROS
  • advantages to different preparations of biological samples
  • data analysis
  • more basic info on mitochondria
  • genetic information of mitochondria
  • mitochondrial transport mechanisms
  • standard protocols/methodologies lecture
  • buffers for respiration (what, why)
  • introduction to subject of lectures
  • mitochondrial diseases
  • more basic information, methodological introduction
  • protocols (why use specific method or reagent)
  • basic methodology
  • buffers
  • membrane potential
  • protocols on the web
  • hand-outs/accessible to students


Special Interest Groups - Focussed Sessions

  • appreciate more special interest groups
  • parallel focus groups with multiple times
  • Special Interest Groups early, then more at end to cover new topics/flexibility in program development
  • break-up into smaller groups (8-10 people)
  • divide the body for special interest groups (heart, muscle, brain)


Poster Sessions

  • poster sessions a very good idea
  • large circulating poster session
  • student presentation very good, maybe extend
  • stressed with flash presentation but good experience
  • interactive abstracts-links to articles


Information Resources

  • prescribe reading
  • isolation is good (no internet)
  • interaction experience/contact is important for idea exchange
  • bring reprints, .pdf files
  • small library of basic textbooks
  • internet access and printers for information access
  • use MiP Society for web access


General Organization

  • keep all participants together for basic reviews at the beginning of lectures
  • open atmosphere is good for learning
  • good atmosphere, excellent interactions
  • more questions/interaction –need to ask questions
  • felt separation from O2k course to Summer School
  • keep flexibility in schedule
  • overlap to course/school is poor
  • small groups for better interaction
  • good to know level of attendees during registration
  • can’t have comprehensive course, but mayb split a bit
  • perfect to have long sessions


General Comments

  • everything was perfect
  • did not expect so much
  • informal atmosphere is good
  • MiP Summer was very good
  • thanks to all presenters
  • pleasure to be here/open/fantastic tutors
  • enjoyed atmosphere/contact with people
  • relaxed atmosphere is good to foster confidence



Labels: MiParea: mt-Awareness 






ORO, 2008