SRot: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr= | |abbr=S(Rot) | ||
|description='''S( | |description='''S(Rot)''': [[Succinate]] supports electron flux through CII via flavin adenine dinucleotide (FADH2). After inhibition of CI by [[rotenone]], the NADH-linked dehydrogenases become inhibited by the redox shift from NAD+ to NADH (Fig. 4.1). Succinate dehydrogenase is activated by succinate and ATP, which explains in part the time-dependent increase of respiration in isolated mitochondria after addition of rotenone (first), succinate and ADP. | ||
|info=[[Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways - Chapter 4.1]] | |info=[[Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways - Chapter 4.1]] | ||
}} | }} |
Revision as of 17:10, 22 January 2016
Description
[[Description::S(Rot): Succinate supports electron flux through CII via flavin adenine dinucleotide (FADH2). After inhibition of CI by rotenone, the NADH-linked dehydrogenases become inhibited by the redox shift from NAD+ to NADH (Fig. 4.1). Succinate dehydrogenase is activated by succinate and ATP, which explains in part the time-dependent increase of respiration in isolated mitochondria after addition of rotenone (first), succinate and ADP.]]
Abbreviation: S(Rot)
Reference: [[Info::Gnaiger 2014 MitoPathways - Chapter 4.1]]
MitoPedia topics: Respiratory substrate-coupling state