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Gnaiger 2017 MiPschool C1

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Apparent Complex IV excess capacity and biochemical thresholds.

Link: MitoEAGLE

Gnaiger E (2017)

Event: MiPschool Obergurgl 2017

COST Action MitoEAGLE


Bioblast editor: Gnaiger E O2k-Network Lab: AT Innsbruck Gnaiger E


Labels: MiParea: Respiration 



Preparation: Permeabilized cells, Permeabilized tissue, Isolated mitochondria 


Pathway: N, S, CIV, NS, ROX 

Event: C1, Review 


Affiliations and support

Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, AT; and Oroboros Instruments, Innsbruck, AT. - [email protected]
Supported by K-Regio project MitoFit. Contribution to European Union Framework Programme Horizon 2020 COST Action CA15203 MitoEAGLE.

References

  1. Lemieux H, Blier PU, Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Rep 7:2840. - »Bioblast link«
  2. Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2017) Impairment of mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480. - »Bioblast link«
  3. Rossignol R, Faustin B, Rocher C, Malgat M, Mazat JP, Letellier T (2003) Mitochondrial threshold effects. Biochem J 370:751-62.