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CZ Prague Jezek P

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CZ Prague Jezek P

Oroboros O2k-Network

O2k-Network
O2k-Network Lab
Petr Jezek (right) with Rodrigue Rossignol (middle) and Guy Brown (left)

Institute of Physiology

Laboratory . No. 75

Academy of Sciences of the Czech Republic

Address Videnska 1083, 14220
City Prague
State/Prov
Country Czech Republic
Weblink
Contact Jezek Petr
Team Dlaskova Andrea, Dvorak Ales, Jaburek Martin, Jezek Jan, Plecita-Hlavata Lydie, Saudek Frantisek, Smolkova Katharina, Spacek Tomas, Uhrova Katerina, Zelenka Jaroslav, Pajuelo-Reguera David
Team previous
Status 2 Power-O2k 2004-
Oroboros Events IOC125, MitoEAGLE 2017 CZ, MiP2014, MiP2013, IOC76, IOC44, IOC39, IOC24
Topics


O2k-Publications

 PublishedReference
Kahancova 2020 Sci Rep2020Kahancov├í A, Sklen├í┼Ö F, Je┼żek P, Dlaskov├í A (2020) Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells. Sci Rep 10:1551.
Smolkova 2020 Sci Rep2020Smolkov├í K, ┼ápa─Źkov├í J, Gotvaldov├í K, Dvo┼Ö├ík A, K┼Öenkov├í A, Hub├ílek M, Holendov├í B, V├ştek L, Je┼żek P (2020) SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2 . Sci Rep 10:8677.
Leguina-Ruzzi 2020 Biomolecules2020Leguina-Ruzzi A, Vodi─Źkov├í A, Holendov├í B, Pavluch V, Tauber J, Engstov├í H, Dlaskov├í A, Je┼żek P (2020) Glucose-induced expression of DAPIT in pancreatic ╬▓-cells. Biomolecules 10:E1026.
Dlaskova 2019 Biochim Biophys Acta Bioenerg2019Dlaskov├í A, ┼ápa─Źek T, Engstov├í H, ┼ápa─Źkov├í J, Schr├Âfel A, Holendov├í B, Smolkov├í K, Plecit├í-Hlavat├í L, Je┼żek P (2019) Mitochondrial cristae narrowing upon higher 2-oxoglutarate load. Biochim Biophys Acta Bioenerg 1860:659-78.
Kahancova 2018 FEBS Lett2018Kahancova A, Sklenar F, Jezek P, Dlaskova A (2018) Regulation of glucose-stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1). FEBS Lett 592:999-1009.
Jezek 2017 Biochim Biophys Acta2017Je┼żek J, Engstov├í H, Je┼żek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62.
Rohlenova 2016 Antioxid Redox Signal2016Rohlenova K, Sachaphibulkij K, Stursa J, Bezawork-Geleta A, Blecha J, Endaya B, Werner L, Cerny J, Zobalova R, Goodwin J, Spacek T, Alisadeh E, Yan B, Nguyen M, Vondrusova M, Sobol M, Jezek P, Hozak P, Truksa J, Rohlena J, Dong L, Neuzil J (2016) Selective disruption of respiratory supercomplexes as a new strategy to suppress Her2high breast cancer. Antioxid Redox Signal 26:84-103.
Zelenka 2016 Oxid Med Cell Longev2016Zelenka J, Dvo┼Ö├ík A, Al├ín L, Zadinov├í M, Haluz├şk M, V├ştek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.
Plecita-Hlavata 2015 J Bioenerg Biomembr2015Plecit├í-Hlavat├í L, Je┼żek J, Je┼żek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76.
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol2015Plecit├í-Hlavat├í L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Je┼żek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57.
Jezek 2015 Antioxid Redox Signal2015Je┼żek J, Dlaskov├í A, Zelenka J, Jab┼»rek M, Je┼żek P (2015) H2O2-activated mitochondrial phospholipase iPLA2╬│ prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GPR40, and regulates insulin secretion in pancreatic ╬▓-cells. Antioxid Redox Signal 23:958-72.
Smolkova 2015 Int J Biochem Cell Biol2015Smolkov├í K, Dvo┼Ö├ík A, Zelenka J, V├ştek L, Je┼żek P (2015) Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells. Int J Biochem Cell Biol 65:125-33.
Zelenka 2015 Oxid Med Cell Longev2015Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.
Konickova 2014 Annals Hepatol2014Konickova R, Vankova K, Vanikova J, Vanova K, Muchova L, Subhanova I, Zadoinova M, Zelenka J, Dvorak A, Kolar M,Strnad H, Rimpelova S, Ruml T, Wong RJ, Vitek L (2014) Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds. Annals Hepatol 13:273-83.
MiPNet18.04 IOC762013-05-28
O2k-Network
Prague CZ, 2013 May 28-29. Oroboros O2k-Workshop on high-resolution respirometry (HRR) and O2k-Fluorometry, IOC76. O2k-Network Lab ┬╗CZ Prague Kalous M.
Jaburek 2013 Int J Biochem Cell Biol2013Jab┼»rek M, Je┼żek J, Zelenka J, Je┼żek P (2013) Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen. Int J Biochem Cell Biol 45:816-25.
Smolkova 2010 J Bioenerg Biomembr2010Smolkov├í K, Bellance N, Scandurra F, G├ęnot E, Gnaiger E, Plecit├í-Hlavat├í L, Je┼żek P, Rossignol R (2010) Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. https://doi.org/10.1007/s10863-009-9267-x
Jezek 2010 Physiol Res2010Je┼żek J, Jab┼»rek M, Zelenka J, Je┼żek P (2010) Mitochondrial phospholipase A2 activated by reactive oxygen species in heart mitochondria induces mild uncoupling. Physiol Res 59:737-47.
Bellance 2009 Int J Biochem Cell Biol2009Bellance N, Benard G, Furt F, Begueret H, Smolková K, Passerieux E, Delage JP, Baste JM, Moreau P, Rossignol R (2009) Bioenergetics of lung tumors: Alteration of mitochondrial biogenesis and respiratory capacity. Int J Biochem Cell Biol 41:2566-77.
Plecita-Hlavata 2009 Int J Biochem Cell Biol2009Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707.
Dlaskova 2008 Int J Biochem Cell Biol2008Dlasková A, Hlavatá L, Jezek J, Jezek P (2008) Mitochondrial Complex I superoxide production is attenuated by uncoupling. Int J Biochem Cell Biol 40:2098-109.
Hlavata 2008 Aging Cell2008Hlavat├í L, Nachin L, Jezek P, Nystr├Âm T (2008) Elevated Ras/protein kinase A activity in Saccharomyces cerevisiae reduces proliferation rate and lifespan by two different reactive oxygen species-dependent routes. Aging Cell 7:148-57.
Spacek 2008 Int J Biochem Cell Biol2008Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40:1522-35.
Zacharovova 2005 Transplant Proc2005Zacharovova K, Berkova Z, Spacek T, Kriz J, Dovolilova E, Girman P, Koblas T, Jezek P, Saudek F (2005) In vitro assessment of pancreatic islet vitality by oxymetry. Transplant Proc 37:3454-6.

O2k-Abstracts

 PublishedReference
Pajuelo-Reguera 2017 MiP20172017
David Pajuelo-Reguera
COX4-1/COX4-2 cell knock-out/knock-in models for the study of cytochrome c oxidase regulation.
Jaburek 2014 Abstract MiP20142014The role of phospholipase A2╬│ in the regulation of mitochondrial uncoupling protein 2ÔÇôdependent antioxidant function.
Jezek 2014 Abstract MiP20142014Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.
Jezek 2013 Abstract MiP20132013Je┼żek P, Je┼żek J, Zelenka J, Dlaskov├í A, Jab┼»rek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2╬│. Mitochondr Physiol Network 18.08.
Zelenka 2013 Abstract MiP20132013Zelenka J, Smolkova K, Dvorak A, Vitek L, Jezek P (2013) Reverse carboxylation glutaminolysis in breast cancer cells. Mitochondr Physiol Network 18.08.
Zelenka J 2013 Abstract MiP20132013Zelenka J, Alan L, Jezek P(2013) Response of cancer cells to mitochondrial DNA damage. Mitochondr Physiol Network 18.08.