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Damiani 2020 Curr Opin Biotechnol

From Bioblast
Publications in the MiPMap
Damiani C, Gaglio D, Sacco E, Alberghina L, Vanoni M (2020) Systems metabolomics: from metabolomic snapshots to design principles. Curr Opin Biotechnol 63:190-199.

Β» PMID: 32278263 Open Access

Damiani C, Gaglio D, Sacco E, Alberghina L, Vanoni M (2020) Curr Opin Biotechnol

Abstract: Metabolomics is a rapidly expanding technology that finds increasing application in a variety of fields, form metabolic disorders to cancer, from nutrition and wellness to design and optimization of cell factories. The integration of metabolic snapshots with metabolic fluxes, physiological readouts, metabolic models, and knowledge-informed Artificial Intelligence tools, is required to obtain a system-level understanding of metabolism. The emerging power of multi-omic approaches and the development of integrated experimental and computational tools, able to dissect metabolic features at cellular and subcellular resolution, provide unprecedented opportunities for understanding design principles of metabolic (dis)regulation and for the development of precision therapies in multifactorial diseases, such as cancer and neurodegenerative diseases.

Copyright Β© 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

β€’ Bioblast editor: Plangger M


Labels: MiParea: Respiration, Instruments;methods 





HRR: Oxygraph-2k 

2020-04