Greenland Expedition CMRC 2004

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Greenland Expedition CMRC 2004

Science and adventure

CMRC Greenland Expedition 2004

An Inuit hunter with sledge on his way over the frozen sea from Qaanaaq (Thule) to Uummannak (North Star Bay, Pituffik, Thule Air Base; March 2004)
During March and April 2004, the Copenhagen Muscle Research Center accomplished a research expedition in the Northwest of Greenland. The overall aim of the project is to elucidate the connection between genes, environment and early appearance of chronic diseases, particularly diabetes 2. Another intention is to throw light on metabolic adaptations in relation to health effects. Part of the project was the evaluation of mitochondrial respiratory parameters measured by high-resolution respirometry in permeabilized muscle fibers. These were prepared from small biopsies of the arm and leg of traditional life-style Inuit hunters, Western life-style Inuits, and a group of 16 Danish participants of the 42-days expedition.
Top right: An Inuit hunter with sledge on his way over the frozen sea from Qaanaaq (Thule) to Uummannak (North Star Bay, Pituffik, Thule Air Base; March 2004).
Green map.jpg
Three units of the Oroboros O2k were part of the expedition - in the northernmost application of high-resolution respirometry (Thule Air Base; 76.4°N, 68.5°E).
  • Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. Scand J Med Sci Sports 25 (Suppl 4):126–34. - »Bioblast link - Open Access«
  • Overview - A flavour of the project
  • Subject 10 - From pre-experiments in Copenhagen to the adventure of the Greenland Expedition
  • Erich Gnaiger (Innsbruck AT) High-resolution respirometry in small biopsies of human muscle: Correlations with body mass index and age. MiP 2005. Pages 14-15.
  • Robert Boushel (Montreal CA) Local adaptations in mitochondrial substrate-specific O2 flux capacity with prolonged, low intensity, whole-body endurance training. MiP2005. Page 16.

I-MED INFO. Die Zeitung der Medizinischen Universität Innsbruck. Nr. 1/Juli 2004


All slides by Erich Gnaiger

Saltin-Bengt 2015-June Salutation GnaigerE.jpg


Subject 10