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Heimler 2022 BEC

From Bioblast

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Bioenergetics Communications        
Gnaiger 2020 BEC MitoPathways
       
Gnaiger Erich et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1.
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Bioenergetics Communications
Publications in the MiPMap
Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older adult women. https://doi.org/10.26124/bec:2022-0002

» Bioenerg Commun 2022.2. Open Access pdf published online 2022-06-28 »Watch the presentation«

Heimler Stephanie R, Phang Howard J, Bergstrom Jaclyn, Mahapatra Gargi, Dozier Stephen, Gnaiger Erich, Molina Anthony JA (BEC 2022.02) Bioenerg Commun

Abstract: BEC.png https://doi.org/10.26124/bec:2022-0002

Graphical abstract

This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in older adult women. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.

Keywords: platelets, resting metabolic rate (RMR), cardiopulmonary exercise testing (CPET), OXPHOS capacity, electron transfer capacity, inverted regression analysis Bioblast editor: Tindle-Solomon Lisa O2k-Network Lab: US CA San Diego Molina AJA, AT Innsbruck Oroboros

ORCID: ORCID.png Heimler Stephanie R, ORCID.png Phang Howard J, ORCID.png Mahapatra Gargi,ORCID.png Gnaiger Erich, ORCID.png Molina Anthony JA

Data availability

Original files are available Open Access at Zenodo repository: https://zenodo.org/record/6760608

Preprint

» Heimler 2022 MitoFit


Labels: MiParea: Respiration, Exercise physiology;nutrition;life style 


Organism: Human  Tissue;cell: Blood cells  Preparation: Permeabilized cells 


Coupling state: OXPHOS, ET  Pathway: F, N, S, Gp, ROX  HRR: Oxygraph-2k 

BEC