Houben 2015 Mitochondrion

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Publications in the MiPMap
Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104.

» PMID: 26219220

Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Mitochondrion

Abstract: This prospective cohort study evaluated the potential of high-resolution respirometry applied to permeabilized muscle fibers for fitness evaluation in French Standardbred racehorses. Fitness evaluation by means of respirometric parameters did not correlate with racing performance registered over the following racing season. However, altered mitochondrial energy metabolism was associated with higher risk of developing exertional rhabdomyolysis, a common cause of exercise intolerance in racehorses. These data represent a first step towards establishing reference values for muscle OXPHOS capacity in this breed. Keywords: Horse, Muscle, Mitochondria, High-resolution respirometry, OXPHOS, Exertional rhabdomyolysis

O2k-Network Lab: BE Liege Votion DM

Labels: MiParea: Respiration, Exercise physiology;nutrition;life style  Pathology: Other 

Organism: Horse  Tissue;cell: Skeletal muscle  Preparation: Permeabilized tissue 

Coupling state: OXPHOS, ET  Pathway: N, S, NS, ROX  HRR: Oxygraph-2k