McManus MJ

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Name McManus Meagan J, PhD
Institution
Meagan McManus

Center for Mitochondrial and Epigenomic Medicine (CMEM)

Children's Hospital of Philadelphia

Colket Translational Research Building

Address 3501 Civic Center Blvd, Room 6100, 19104
City Philadelphia
State/Province Pennsylvania (PA)
Country USA
Email [email protected]
Weblink
O2k-Network Lab US PA Philadelphia Wallace DC


Labels: Field of research: Basic, Pharmacological 



Publications

 PublishedReference
Yardeni 2021 Proc Natl Acad Sci U S A2021Yardeni T, Cristancho AG, McCoy AJ, Schaefer PM, McManus MJ, Marsh ED, Wallace DC (2021) An mtDNA mutant mouse demonstrates that mitochondrial deficiency can result in autism endophenotypes. Proc Natl Acad Sci U S A 118:e2021429118.
Marquez 2020 J Am Heart Assoc2020Marquez AM, Morgan RW, Ko T, Landis WP, Hefti MM, Mavroudis CD, McManus MJ, Karlsson M, Starr J, Roberts AL, Lin Y, Nadkarni V, Licht DJ, Berg RA, Sutton RM, Kilbaugh TJ (2020) Oxygen exposure during cardiopulmonary resuscitation is associated with cerebral oxidative injury in a randomized, blinded, controlled, preclinical trial. J Am Heart Assoc 9:015032.
McManus 2019 Cell Metab2019McManus MJ, Picard M, Chen HW, De Haas HJ, Potluri P, Leipzig J, Towheed A, Angelin A, Sengupta P, Morrow RM, Kauffman BA, Vermulst M, Narula J, Wallace DC (2019) Mitochondrial DNA variation dictates expressivity and progression of nuclear DNA mutations causing cardiomyopathy. Cell Metab 29:78-90.
Morrow 2017 Proc Natl Acad Sci U S A2017Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10.

Abstracts

 PublishedReference
McManus 2016 Abstract MitoFit Science Camp 20162016A multi-tiered mitochondrial approach to predictive biomarkers of neurodegenerative disease.
McManus 2015 Abstract MiP20152015The etiology of age-dependent disease: a story of two genomes.

Participated at

Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network

Meagan J McManus: Visiting scientist at the Oroboros O2k-Laboratory

  • September 14 to October 11 2015