Nedergaard J

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BEC 2020.1 Mitochondrial physiology
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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Nedergaard J

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


COST Mentor: Mentor

WG3 Leader - Management Committee MitoEAGLE
Name Nedergaard Jan, Dr.
Jan Nedergaard
Department of Metabolic Research

The Arrhenius Laboratories F3
Stockholm University

Address , S-106 91
City Stockholm
Country Sweden
Email [email protected]
O2k-Network Lab SE Stockholm Nedergaard J



Gao 2022 Biochim Biophys Acta Bioenerg2022Gao Y, Shabalina IG, Braz GRF, Cannon B, Yang G, Nedergaard J (2022) Establishing the potency of N-acyl amino acids versus conventional fatty acids as thermogenic uncouplers in cells and mitochondria from different tissues.
Nabben 2011 Biochim Biophys Acta2011Nabben M, Shabalina IG, Moonen-Kornips E, van Beurden D, Cannon B, Schrauwen P, Nedergaard J, Hoeks J (2011) Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice. Biochim Biophys Acta 1807:1095-105.
Cannon 2008 Methods Mol Biol2008Cannon B, Nedergaard J (2008) Studies of thermogenesis and mitochondrial function in adipose tissues. Methods Mol Biol 456:109-21.


Gao 2019 MiPschool Coimbra2019
Effects on mitochondrial respiration of N-acyl amino acids versus common fatty acids.
Shabalina 2018 MiP20182018
Irina Shabalina
Elovl2-ablation leads to mitochondrial phospholipid remodeling and reduced oxidative phosphorylation capacity in mouse liver mitochondria.
Shabalina 2017 Abstract MITOEAGLE Barcelona2017
Control of UCP1 activity in brown fat mitochondria.
Shabalina 2017 MiP20172017
Irina Shabalina
In UCP1-ablated mice, prolonged cold exposure promotes mitochondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat.
Nedergaard 2017 MiP20172017
Jan Nedergaard
Creatine effect in mitochondria from different tissues.
Kalinovich 2015 Abstract MiP20152015UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice.
Shabalina 2015 Abstract MiP20152015The metabolically inert environmental pollutants perfluorinated fatty acids directly activate uncoupling protein 1 in brown-fat mitochondria.
Mahdaviani 2014 Abstract MiP20142014Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure.
Shabalina 2013 Abstract IOC792013Shabalina IG (2013) Enhanced Complex I but low Complex II substrate-derived ROS production rates in mice, prematurely aging due to enhanced mitochondrial DNA mutation rate. Mitochondr Physiol Network 18.07
Shabalina 2013 Abstract MiP20132013Shabalina IG, Petrovic N, Kalinovich AV, Cannon B, Nedergaard J (2013) Comparative study of brown and white adipose tissue mitochondria in mice upon cold acclimation. Mitochondr Physiol Network 18.08.

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