Selwood 2017 US Patent

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Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1.

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Selwood David L, Baker David, Szabadkai Gyorgy, Duchen Michael R, Hill Julia M, Warne Justin (2017) US Patent

Abstract: The present invention relates to conjugates of cyclosporin with quinolium mitochondrial targeting groups, and their therapeutic uses.

Bioblast editor: Kandolf G O2k-Network Lab: UK London Duchen MR


Labels: MiParea: Respiration, Pharmacology;toxicology 

Stress:Ischemia-reperfusion  Organism: Mouse  Tissue;cell: Liver  Preparation: Isolated mitochondria 


Coupling state: LEAK, OXPHOS, ET  Pathway: N, ROX  HRR: Oxygraph-2k 

Labels, 2018-02