Skulachev 1998 Biochim Biophys Acta

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Skulachev VP (1998) Uncoupling: new approaches to an old problem of bioenergetics. Biochim Biophys Acta 1363:100-124.

» PMID: 9507078 Open Access

Skulachev VP (1998) Biochim Biophys Acta

Abstract: The action of both artificial and natural uncouplers is mediated by some proteins. Uncoupling is of more general physiological importance than heat production in brown fat. In particular, it is involved in the cellular defence system preventing formation of superoxide.


O2k-Network Lab: RU Moscow Skulachev VP


Labels:

Stress:Oxidative stress;RONS 


Preparation: Isolated mitochondria 

Regulation: Coupling efficiency;uncoupling, Uncoupler  Coupling state: LEAK, ET