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• Ohashi 2012 Nat Commun
  ...K (2012) Identification and characterization of a human mitochondrial NAD kinase . Nat Commun 3:1248. ...uman HEK293A cells. C5orf33 mRNA is more abundant than human cytosolic NAD kinase mRNA in almost all tissues examined. We further show by database searches t
  1 KB (202 words) - 17:13, 21 February 2022
• Bartrons 2004 Cryobiology
  ...N, Navarro-Sabaté A, Bartrons R (2004) Activation of AMP-dependent protein kinase by hypoxia and hypothermia in the liver of frog Rana perezi. Cryobiology 49 |authors=Bartrons M, Ortega E, Obach M, Calvo MN, Navarro-Sabate A, Bartrons R
  2 KB (230 words) - 09:28, 9 November 2016
• AMPK
  |description='''AMP-activated protein kinase''' is a regulatory protein which acts as crucial cellular energy sensor by sensing AMP, [[ADP]] and/or ...nserving ATP by downregulating anabolic pathways. AMPK is a heterotrimeric protein (catalytic α-subunit and regulatory β- and γ-subunits). The well-known o
  2 KB (289 words) - 08:58, 21 May 2012
• Kang 2017 Mol Cell
  ...sociated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex. Mol Cell 67:457-70. ...it of TIM22 provides an exciting and unexpected link between mitochondrial protein import and Sengers syndrome.
  2 KB (288 words) - 22:38, 1 December 2018
• O´Gorman 1997 FEBS Lett
  ...Dolder M, Koretsky AP, Brdiczka D, Wallimann T (1997) The role of creatine kinase in inhibition of mitochondrial permeability transition. FEBS Lett 414:253-7 ...e. No malate release occurred with complexes containing octameric creatine kinase under the same conditions.
  2 KB (220 words) - 15:37, 15 June 2015
• Chowdhury 2012 Brain
  ...NA, Fernyhough P (2012) Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfun |authors=Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P
  3 KB (422 words) - 08:23, 21 February 2020
• Nin 2012 J Biol Chem
  ...acetylase activation induced by protein kinase A and AMP-activated protein kinase. J Biol Chem 287:23489-501. ...s provide new insight on the ''in vivo'' mechanism of SIRT1 regulation and a new avenue for the development of pharmacological SIRT1 activators targeted
  2 KB (363 words) - 12:17, 8 November 2016
• Roth 2010 Aging (Albany NY)
  |title=Flach RJ, Bennett AM (2010) MAP kinase phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease. Aging (Al ...sarcopenia and overnutrition in a pathophysiological pathway that leads to a loss of skeletal muscle mitochondrial function. With the increasing aging p
  2 KB (268 words) - 12:45, 19 March 2015
• Djeungoue-Petga 2019 Cell Death Dis
  ...Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. ...etga MA, Lurette O, Jean S, Hamel-Cote G, Martín-Jimenez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E
  2 KB (334 words) - 10:36, 27 January 2020
• Hardeland 2009 Biofactors
  |title=Hardeland R (2009) Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 35:183-92. ...ma membrane, such as an orphan GPCR, GPR50, and the PDZ domain scaffolding protein MUPP1, effects which negatively or positively influence signaling capacity.
  2 KB (320 words) - 08:06, 21 February 2020
• Kowluru 2010 Diabetes
  |title=Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ. (2010) Protein farnesylation-dependent raf/erk signaling links to cytoskeletal remodeling |authors=Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ
  2 KB (321 words) - 08:22, 31 March 2017
• Xiong 2016 Hypertension
  ...nsient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. ...mitochondrial dysfunction. Dietary capsaicin supplementation may represent a promising intervention for the primary prevention of coronary heart disease
  3 KB (432 words) - 19:28, 29 February 2020
• Qvit 2022 Pharmaceuticals (Basel)
  ...of cardiac troponin I phosphorylation by delta protein kinase C (δPKC) as a treatment for ischemia-reperfusion injury. https://doi.org/10.3390/ph150302 ...injury, and that a cTnI/δPKC interaction inhibitor should be considered as a therapeutic target to reduce cardiac injury after myocardial infarction.
  2 KB (280 words) - 18:55, 6 December 2022
• Garcia-Roves 2008 J Biol Chem
  ...Zierath JR (2008) Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal mu ...up> mice, independent of changes in fiber type composition. In conclusion, a single nucleotide mutation (R225Q) in the AMPK gamma3 subunit is associated
  3 KB (346 words) - 09:46, 15 December 2014
• Pape 2018 Nutrients
  ...ration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990. |authors=Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH
  3 KB (372 words) - 10:02, 29 July 2019
• Dejean 2002 Biochem Biophys Res Comm
  ...DNA genes was unchanged. It is concluded that the Ras/cAMP/protein kinase A pathway is part of the regulatory circuit controlling biogenesis of the oxi |mipnetlab=FR Pessac Diolez P, FR Bordeaux Devin A
  2 KB (243 words) - 12:43, 16 February 2018
• Kristensen 2013 PLoS One
  ...in treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS One 8:e53533. ...he respiration defect compared to the WT mice. Metformin did not influence protein activities or expressions in either WT or AMPK KD mice.
  3 KB (396 words) - 04:10, 12 February 2020
• Costa 2013 Cell Death Dis
  ...(2013) ''Drosophila'' Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467. ...rap1 function with Pink1 and parkin. We show that loss of Trap1 results in a decrease in mitochondrial function and increased sensitivity to stress, and
  3 KB (340 words) - 12:14, 27 March 2018
• Stefan 2022 Abstract Bioblast
  ...> (2022) Tracking patient-mutation and lead-molecule driven alterations of kinase activity conformations. '''Bioblast 2022: BEC Inaugural Conference.''' In: ...icine-oriented KinCon biosensor concept is not restricted to recordings of kinase drug efficacies/specificities. We have first evidence that such conformatio
  3 KB (438 words) - 08:44, 28 July 2022
• Poudel 2019 Can J Physiol Pharmacol
  |title=Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L (2019) Berberine hydrochlorid |authors=Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L
  2 KB (330 words) - 16:17, 11 February 2020

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