Talk:MitoEAGLE data: muscle
|Australia||Melbourne||Bishop David J|
|Brazil||São Paulo||Ferreira Julio Cesar B|
|Brazil||Jaboticabal, SP||Garcia Geovana S|
|Canada||Antigonish||Kane Daniel A|
|Canada||Rimouski||Blier Pierre U|
|Canada||Vancouver||Boushel Robert C|
|Canada||Edmonton (Alberta)||Lemieux Helene|
|Czech Republic||Prague||Elkalaf Moustafa|
|Czech Republic||Pilsen||Kuncova J|
|Czech Republic||Hradec Králové||Waldauf P|
|Czech Republic||Pilsen||Markova Michaela|
|Czech Republic||Prague 10||Krajcova Adela|
|Denmark||Hvidovre||Nehlin Jan O|
|Denmark||Copenhagen N||Mortensen OH|
|France||Grenoble cedex 9||Dubouchaud Herve|
|France||Bordeaux cedex||Mourier A|
|France||Grenoble Cedex 9||Schlattner Uwe|
|France||Paris||Petit Patrice X|
|France||Montpellier Cedex 1||Chabi Beatrice|
|Germany||Bremerhaven||Mark Felix Christopher|
|Greece||Athens||Trougakos Ioannis P|
|Ireland||Dublin||Porter Richard K|
|Israel||Jerusalem||Saada Reisch Ann|
|Israel||Rishon Le Zion||Hachmo Yafit|
|Italy||Milan||De Palma Clara|
|Italy||Bologna||Genova Maria Luisa|
|Netherlands||Maastricht||Van Polanen N|
|Netherlands||BT Amsterdam||Jaspers Richard T|
|Netherlands||Amsterdam||De Goede Paul|
|Niederlande||ER Masstricht||De Wit-Verheggen V|
|Niederlande||ER Masstricht||De Theije C|
|Norway||Tromsoe||Larsen Terje S|
|Norway||Tromsoe||Schots Pauke C|
|Norway||Tromsoe||Jansen Kirsten M|
|Norway||Bergen||Tronstad Karl Johan|
|Poland||Warsaw||Kampa Rafal Pawel|
|Portugal||Cantanhede||Martins Joao D|
|Portugal||Coimbra||Martins Marques T|
|Portugal||Coimbra||Pereira Susana P|
|Romania||Timisoara||Muntean Danina M|
|Singapore||Singapore||Hausenloy Derek J|
|South Africa||Smith James|
|Spain||Armilla (Granada)||Acuna-Castroviejo Dario|
|Spain||Barcelona||De la Torre Lara J|
|Spain||Barcelona||Gama Perez Pau|
|Spain||Armilla, Granada||Escames Germaine|
|Spain||A Coruña||Blanco FJ|
|Spain||Armilla (Granada)||Fernandez-Ortiz Marisol|
|Spain||Barcelona||Garcia-Roves Pablo Miguel|
|Spain||Granada||Lopez Garcia Luis Carlos|
|Sweden||Stockholm||Cardinale Daniele A|
|Switzerland||Lausanne||Morato Fornaguera L|
|The Netherlands||Wageningen||Van der Ende Miranda|
|The Netherlands||BT Amsterdam||Wuest Rob CI|
|USA||Fort Collins||Chicco Adam J|
|USA||Colorado Springs||Jacobs RA|
|USA||College Station||White-Springer Sarah H|
|USA||Gainesville||Hepple Russell T|
|USA||Ann Arbor||Beard Daniel A|
|USA||Little Rock||Porter Craig|
|USA||St Louis||Welch R|
|USA||College Station||Latham C|
|USA||Gainesville||Wohlgemuth Stephanie E|
|USA||Boca Raton||Khamoui Andy V|
|USA||Baton Rouge||Irving Brian A|
|USA||Orlando||Coen Paul M|
|USA||Baton Rouge||Axelrod Christopher L|
|USA||Torrance||Rossiter Harry B|
|United Kingdom||Leeds||Boyle JP|
|United Kingdom||Birmingham||Thakker A|
|United Kingdom||Nottingham||Chakrabarti Lisa|
|United Kingdom||Loughborough||Ebanks Brad|
|United Kingdom||Birmingham||Ashcroft S|
|United Kingdom||Plymouth, Devon||McKenna Helen T|
|United Kingdom||Birmingham||Garten Antje|
|United Kingdom||Oxford||Makrecka-Kuka Marina|
|United Kingdom||Brighton||Moore Anthony L|
|United Kingdom||Cambridge||Shiroma Jonathan G|
|United Kingdom||Birmingham||Joanisse S|
|United Kingdom||Cambridge||Murray Andrew James|
|United Kingdom||London||Szabadkai Gyorgy|
|United Kingdom||Manchester||Giakoumaki I|
|United States||Providence||Siamwala J|
Comments and discussion
- Skeletal muscle is the main tissue we are studying in the lab. - Beatrice Chabi (2016).
- For the kind of work group, our expertise is certainly most on muscle tissue (skeletal and heart), although we also worked on all kinds of permeabilized cells (primary cells and cell lines). For all these, we have extended data sets, mainly rat, but also human, from diverse experimental setups (nutritional regimen, exercise, drugs ...). - Uwe Schlattner (2016).
- In my working group we are mainly interested in muscle, especially focusing on aging and sarcopenia (using animal models). I would be happy if new cooperations could be formed through the COST Action. I could imagine working on a joint review article. Next to examining muscle from mouse models, we are studying biopsies from human heart muscle and liver, but there is no published data on these studies yet. - Susanne Klaus (2016). Translated by Sandra Fleischmann
- I am working in the field of mitochondrial biochemistry since many years. In detail my coworkers and I are carrying out studies on the regulation of ATP synthase and respiratory complexes in swine heart mitochondria as biological model of mammalian mitochondria. Some comparative aspects of mitochondrial bioenergetics and ATP synthase responses are also investigated in bivalve mollusk mitochondria. - Alessandra Pagliarani (2016).
- We are mostly interested in two WG: (1) Since we are working mostly with heart and muscles, we are interested in WG 2 - MITOEAGLE data repository in muscle and other tissues. (2) WG 1 - Standard operating procedures and user requirement document: Protocols, terminology, documentation. Since we have an expertise in fatty acid metabolism, we are specially interested in experimental protocols for the evaluation of mitochondrial capacities regarding fatty acid metabolism. Of course our parts of the WG are also in our interest. - Marina Makrecka-Kuka, Edgars Liepinsh (2016).
- My role in Mito-EAGLE would be mainly in WG 2 and 4, with a focus on skeletal and cardiac muscle and cultured cardiomyocytes and endothelial cells. I would particularly like to bridge the gap between the group leaders and young investigators, trying to represent the young people who are the active users of the OROBOROS equipment. This will fit in nicely with the goals in WG1. ... Major congratulations on obtaining this beautiful collaborative grant! Very glad to see this network getting the recognition it deserves! Looking forward to being part of this! - Rob C Wuest (2016).
- We mostly work with cultured human skeletal muscle cells, from different donor groups such as lean, obese, type 2 diabetics, as well as muscle cells from athletes. We are interested in collaboration with our cells and measurements on energy metabolism and mitochondral function. - Arild Rustan (2016).
- Please, find enclosed my declaration to participate with my team in the following workgroups: WG1, WG2, WG3, WG4. We are now involved and have been in not a distant past – in studying of the following cell /tissue types:
- Blood cells, with particular emphasis on platelets and lymphocytes – isolated from animals and humans.
- Endothelial cells, fibroblasts, neurocytes (neuroblastoma), astrocytes, cancer cell lines – predominantly cultured.
- Hepatocytes, cardiomyocytes, cell isolated from brain – isolated from lab animals. - Cezary Watala (2016).
- I have already contacted the portuguese CNC to nominate me for the MC of theaction. Concerning my active participation, taking into account the type of work we do in my lab I could be included in all WGs. As you know we work with mitochondria from liver, muscle and fat, as well as cultured cells from different origins (WG2-4). The elaboration of SOPs (WG1) we can certainly contribute (see the book I edited on Mitochondrial Bioenergetics and in which you contribute a chapter). I believe that everybody can be part of the WG5, but as the coordinators of the action, you and Sandra should decide what is best for the success of the action. - Carlos Palmeira (2016).
- As you know, I have received the MC nomination from our CNC in Bucharest (Ms Elena Dinu) for my colleague, Rodica Lighezan and myself. My expertise is most on muscle tissue (in particular, heart) and also, liver - so I will go for WG2 if this is fine with you. However, Both my colleague and I are mostly interested in performing respirometry in blood cells (and this is what we will start to try in the near future); thus, you decide whether we can fit both of us in WG4, or only her. Also, in order to extend the Network in other Romanian cities with powerful state medical universities, Cluj-Napoca (as you know) and Tg Mures - 2 young men, Bela Kiss and Ovidiu Cotoi have been proposed as substitute members (for gender balance too). In particular, we want to jointly ”explore” the exciting fields of mitochondrial ”hidden toxicity” and dynamics, respectively since the former colleague is a toxicologist and the latter a pathologist. I wish you good luck and I am indeed happy and proud to be part of this growing network. - Danina M Muntean (2016).
- I took a look to the MoU and the different working groups. You know well my research focus and having this into account I am interested in actions related to Working group 1 (Respirometric reference protocols, Interlaboratory proficiency test, Instrumental platforms). Working group 2 and 3: I have generated multiple mitochondrial respiration data sets in different mouse tissues (mainly in skeletal muscle, hypothalamus, liver and white adipose tissue). Currently we are also performing these assays in white adipose tissue from human patients. Hence I am interested in all milestones of WG 2 and 3. WG 5 is related to WG 1 and as you know I have interest in training, dissemination and also together with my collaborators (if needed) we could help with data sets and a data interpretation. Overall, I have a general interest on this Action and my active role in MITOEAGLE could be discussed. I could be of help participating in some of the tasks where my expertise and interest fit best. We will be forming and interdisciplinary research group with four group leaders: JC Perales, R Guimera, M Sales-Pardo and PM Garcia-Roves with two different affiliations, University of Barcelona (JCP and PMG-R - Energy metabolism) and University Rovira I Virgili (RG and MS – Data base, statistics, data mining). - Pablo M Garcia-Roves (2016).
- Congratulations on the considerable progress with MITOEAGLE! I am keen to participate in this exciting project and I’m sure I can make a valuable contribution to it's success. I have extensive experience performing respirometry assays in human muscle biopsies, myoblasts/tubes and mouse tissues in the contexts of aging, obesity, exercise and inactivity. I feel that I could contribute to any of the five working groups, but particularly to WG2, WG4, and WG5. I am also happy and willing to serve on the Management Committee if needed. Again, congratulations on organizing such an exciting project. - Paul M Coen (2016).
- In particular, my team can participate with studies about the mitochondrial function in relation to the supramolecular organization of the respiratory chain where the dynamic presence of the respiratory supercomplexes is a way to shift between the main metabolic fluxes of NAD- and FAD-dependent substrates in different metabolic conditions of the cell. Besides my basic studies on the enzyme interactions with the Coenzyme Q pool, I recently joined an Italian consortium of University laboratories whose target is to shed light on the molecular mechanisms underpinning muscle weakness and reduced muscle mass (sarcopenia) in ageing and attenuated response to exercise training stimuli in the elderly; both animal models and human subjects will be analyzed. - Maria Luisa Genova (2016).
- I would be interested to be involved with WG1 and WG2. In particular, I am interested in contributing to developing protocols for multicenter quality control among labs, and for permeabilized muscle bundle respirometry. - Harry B Rossiter (2016).
- Our main research subject is the heart muscle cells. So, we could contribute in datasets for several animals (rat, trout, mice [WT and KOs]). In collaboration with WG1, it would be possible to report data in standardized format. - Marko Vendelin (2016)
- As research group working in the field of skeletal muscle research (development,function and regeneration, metabolic pathways, signalling, and energy metabolism and skeletal muscle in special condition-ischemia, hypoxia, sepsis) we found several topics in the COST Action particularly interesting. Indeed, we are highly interested in effects of media and protocols on experimental readouts in cell cultures (please see Pirkmajer 2011 Am J Physiol Cell Physiol and Rajh 2016 PLOS ONE). We therefore find the focus on harmonization and validation of protocols and terminology especially important. - Tomaz Mars (2016).
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