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Uncoupling protein 2

From Bioblast

high-resolution terminology - matching measurements at high-resolution

Uncoupling protein 2


Uncoupling protein 2 (UCP2) belongs to the gene family of uncoupling proteins. Whereas UCP1 acts as an uncoupler, this may not be the case for UCP2.

Abbreviation: UCP2

MitoPedia topics: Uncoupler 

UCP2 controls mitochondrial fission in hypothalamic neurons, based on the amount of glucose in the blood, which controls the activity of glucose-excited neurons, and thus regulates blood glucose.[1]


  1. โ†‘ Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S (2016) UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness. Cell 164:872-83.