Difference between revisions of "Bioblast alert 2015"
From Bioblast
| Line 10: | Line 10: | ||
*O2k-Publication: '''Heart failure and mitochondrial dysfunction'''. Increased OXPHOS capacity after cold preservation of the human heart – a paradox resolved by a dyscoupling mechanism. | *O2k-Publication: '''Heart failure and mitochondrial dysfunction'''. Increased OXPHOS capacity after cold preservation of the human heart – a paradox resolved by a dyscoupling mechanism. | ||
::[[Lemieux 2011 Int | ::[[Lemieux 2011 Int J Biochem Cell Biol|Lemieux H, Semsroth S, Antretter H, Hoefer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol 43: 1729–1738]]. >>> [[Talk:Lemieux 2011 Int J Biochem Cell Biol|Discussion: Complementary results on the PGC-1a pathway]]. | ||
*'''[[Scientific service]]''': '''[[Tissue storage]]''' on ice is possible for limited periods of time (several hours) with preservation of mitochondrial respiratory function, as evaluated with [[SUIT protocol]]s. | *'''[[Scientific service]]''': '''[[Tissue storage]]''' on ice is possible for limited periods of time (several hours) with preservation of mitochondrial respiratory function, as evaluated with [[SUIT protocol]]s. | ||
| Line 22: | Line 22: | ||
*'''[http://www.oroboros.at/index.php?ioc66 O2k-Fluorometry Workshop IOC66]''': 2012-03-15 to 16. OROBOROS INSTRUMENTS, Innsbruck, Austria. The first series of the '''[[O2k-Fluorescence Module]]''' will be delivered in '''April 2012''', for orders received by end of January 2012. | *'''[http://www.oroboros.at/index.php?ioc66 O2k-Fluorometry Workshop IOC66]''': 2012-03-15 to 16. OROBOROS INSTRUMENTS, Innsbruck, Austria. The first series of the '''[[O2k-Fluorescence Module]]''' will be delivered in '''April 2012''', for orders received by end of January 2012. | ||
*O2k-Publication: A key question on the separation of '''qualitative versus quantitative change of mitochondrial function''' is addressed in a new O2k-Publication. Does training induce mild uncoupling? Are sedentary humans healthy controls? | *O2k-Publication: A key question on the separation of '''qualitative versus quantitative change of mitochondrial function''' is addressed in a new O2k-Publication. Does training induce mild uncoupling? Are sedentary humans healthy controls? | ||
::[[ | ::[[Pesta_2011_Am J Physiol Regul Integr Comp Physiol|Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, Kobel C, Parson W, Burtscher M, Schocke M, Gnaiger E (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: R1078–R1087]]. | ||
*'''[[Scientific service]]''': [[ETS capacity]] plays a key role in such analyses, which cannot be achieved quantitatively without careful '''[[Optimum uncoupler concentration|uncoupler titrations]]. | *'''[[Scientific service]]''': [[ETS capacity]] plays a key role in such analyses, which cannot be achieved quantitatively without careful '''[[Optimum uncoupler concentration|uncoupler titrations]]. | ||
*Term of the month: '''[[Basal respiration]]''' - a hallmark of high-resolution respirometry is a matching '''high-resolution terminology'''. | *Term of the month: '''[[Basal respiration]]''' - a hallmark of high-resolution respirometry is a matching '''high-resolution terminology'''. | ||
Revision as of 00:38, 22 November 2011
Bioblast alert
Bioblast alert messages are prepared by the Bioblast editorial board to draw attention to specific topics on the Bioblast wiki. Bioblast alert is for information purposes only, it is not intended to be an advertisement. Topics submitted by the general scientific community are very welcome.
Bioblast alert 2011(02): 2011-11-17
- O2k-Publication: Heart failure and mitochondrial dysfunction. Increased OXPHOS capacity after cold preservation of the human heart – a paradox resolved by a dyscoupling mechanism.
- Scientific service: Tissue storage on ice is possible for limited periods of time (several hours) with preservation of mitochondrial respiratory function, as evaluated with SUIT protocols.
- Term of the week: Uncoupled, non-coupled, dyscoupled - a hallmark of high-resolution respirometry is a matching high-resolution terminology.
- Evaluate an example of low-resolution terminology: Uncoupling was studied in stressed cells by measurement of coupled respiration, evaluation of uncoupled respiration after inhibition with oligomycin, and FCCP titration to quantify uncoupled respiration.
Bioblast alert 2011(01): 2011-11-11
- O2k-Fluorometry Workshop IOC66: 2012-03-15 to 16. OROBOROS INSTRUMENTS, Innsbruck, Austria. The first series of the O2k-Fluorescence Module will be delivered in April 2012, for orders received by end of January 2012.
- O2k-Publication: A key question on the separation of qualitative versus quantitative change of mitochondrial function is addressed in a new O2k-Publication. Does training induce mild uncoupling? Are sedentary humans healthy controls?
- Scientific service: ETS capacity plays a key role in such analyses, which cannot be achieved quantitatively without careful uncoupler titrations.
- Term of the month: Basal respiration - a hallmark of high-resolution respirometry is a matching high-resolution terminology.
