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Difference between revisions of "Bolivia-Mount Chacaltaya 2012"

From Bioblast
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''"The main body of the project is to combine extensive physiology measurements during and after acclimatization for the first time with gene expression, proteomics, epigenetics and microRNA measurements to describe the molecular mechanisms of human acclimatization to high altitude. ..''
''"The main body of the project is to combine extensive physiology measurements during and after acclimatization for the first time with gene expression, proteomics, epigenetics and microRNA measurements to describe the molecular mechanisms of human acclimatization to high altitude. ..''


[[File:ORO-Lab_Chacaltaya-CatherineLee_4684_01.JPG|250px|left|Catherine Le operating the OROBOROS O2k instruments with vastus lateralis biopsies at Chacaltaya (Jul/Aug 2012).]
[[File:Chacaltaya-CatherineLee.jpg|250px|left|Catherine Le operating the OROBOROS O2k instruments with vastus lateralis biopsies at Chacaltaya (Jul/Aug 2012).]


''Baseline testing was done in Eugene Oregon in mid-May over the course of about a week. Only one muscle biopsy is planned, at rest through the study. Then in July we will be in Bolivia at 17,200 feet. Subjects come in groups of two, have an acute exposure biopsy then another one after 16 days. The elapsed time from start of first subject to end of the last subject is about 5 weeks. .. but we are stuck with no machine to make the measurements on."''
''Baseline testing was done in Eugene Oregon in mid-May over the course of about a week. Only one muscle biopsy is planned, at rest through the study. Then in July we will be in Bolivia at 17,200 feet. Subjects come in groups of two, have an acute exposure biopsy then another one after 16 days. The elapsed time from start of first subject to end of the last subject is about 5 weeks. .. but we are stuck with no machine to make the measurements on."''
In the framework of the [[MitoCom|K-Regio project MitoCom Tyrol]], OROBOROS INSTRUMENTS sent two Oxygraph-2k test units to Oregon in May. The newest Series E has 14 instead of 20 kg, which is of particular advantage for shipment of the instruments from Eugene to Bolivia and taking them up to Mt. Chacaltaya in July.
In the framework of the [[MitoCom|K-Regio project MitoCom Tyrol]], OROBOROS INSTRUMENTS sent two Oxygraph-2k test units to Oregon in May. The newest Series E has 14 instead of 20 kg, which is of particular advantage for shipment of the instruments from Eugene to Bolivia and taking them up to Mt. Chacaltaya in July.

Revision as of 13:02, 18 May 2015

AltitudeOmics 2012

Rob Roach explains the AltitudeOmics 2012 project, with the two OROBOROS O2k at 5,200 m in one of the labs at Chacaltaya, Bolivia. Dr.a Isabel Moreno (right) belongs to the physics staff of the Chacaltaya laboratory (Jul/Aug 2012).

"If we can figure out how the body responds to hypoxia there are implications for cancer, heart, lung and blood disease. It could have enormous reach." - Robert Roach, Director of the Altitude Research Center, School of Medicine, University of Colorado, USA

MitoCom Tyrol participated in the AltitudeOmics 2012 project - scientists were using high-resolution respirometry to study mitochondrial function at 5,240 m in Bolivia, Mt. Chacaltaya.

Β»Chacaltaya GAW Station

High altitude study in Bolivia at Mt. Chacaltaya (5,200 m)

Dr. Robert Roach contacted Dr. Erich Gnaiger in April 2012: "The main body of the project is to combine extensive physiology measurements during and after acclimatization for the first time with gene expression, proteomics, epigenetics and microRNA measurements to describe the molecular mechanisms of human acclimatization to high altitude. ..

[[File:Chacaltaya-CatherineLee.jpg|250px|left|Catherine Le operating the OROBOROS O2k instruments with vastus lateralis biopsies at Chacaltaya (Jul/Aug 2012).]

Baseline testing was done in Eugene Oregon in mid-May over the course of about a week. Only one muscle biopsy is planned, at rest through the study. Then in July we will be in Bolivia at 17,200 feet. Subjects come in groups of two, have an acute exposure biopsy then another one after 16 days. The elapsed time from start of first subject to end of the last subject is about 5 weeks. .. but we are stuck with no machine to make the measurements on." In the framework of the K-Regio project MitoCom Tyrol, OROBOROS INSTRUMENTS sent two Oxygraph-2k test units to Oregon in May. The newest Series E has 14 instead of 20 kg, which is of particular advantage for shipment of the instruments from Eugene to Bolivia and taking them up to Mt. Chacaltaya in July.