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Boyle JP

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Boyle JP


MitoPedia topics: EAGLE 

COST: Participant

COST WG2: WG2 COST WG3: WG3


Name Boyle John, Dr.,

Senior Lecturer

Institution
John Boyle
Division of Cardiovascular and Diabetes Research

Leeds Institute of Cardiovascular and Metabolic Medicine

Faculty of Medicine and Health

Address University of Leeds, LS2 9JT
City Leeds
State/Province
Country United Kingdom
Email [email protected]
Weblink
O2k-Network Lab UK Leeds Peers C


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Publications

 PublishedReference
Chang 2020 J Biol Chem2020Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35.
Chang 2019 Br J Anaesth2019Chang L, Daly C, Miller DM, Allen PD, Boyle JP, Hopkins PM, Shaw MA (2019) Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals. Br J Anaesth 122:613-21.
Fowler 2019 Int J Mol Sci2019Fowler ED, Hauton D, Boyle J, Egginton S, Steele DS, White E (2019) Energy metabolism in the failing right ventricle: limitations of oxygen delivery and the creatine kinase system . Int J Mol Sci 20:1805.
Houghton 2018 Free Radic Biol Med2018Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309.
Cahill 2015 J Biol Chem2015Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19.
Linley 2012 Proc Natl Acad Sci U S A2012Linley JE, Ooi L, Pettinger L, Kirton H, Boyle JP, Peers C, Gampera N (2012) Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons. Proc Natl Acad Sci U S A 109:1578-86
Wuest 2012 Am J Physiol Heart Circ Physiol2012Wuest RC, Myers DS, Stones R, Benoist D, Robinson PA, Boyle JP, Peers C, White E, Rossiter HB (2012) Regional skeletal muscle remodeling and mitochondrial dysfunction in right ventricular heart failure. Am J Physiol Heart Circ Physiol 302: H402-H411.
Boyle 2012 Brain Res2012Boyle JP, Hettiarachchi NT, Wilkinson JA, Pearson HA, Scragg JL, Lendon C, Al-Owais MM, Kim CB, Myers DM, Warburton P, Peers C (2012) Cellular consequences of the expression of Alzheimer's disease-causing presenilin 1 mutations in human neuroblastoma (SH-SY5Y) cells. Brain Res 1443:75-88.

Abstracts

 PublishedReference
Chang 2018 Biophys J2018Mitochondrial dysfunction in malignant hyperthermia susceptible skeletal muscle.
Chang 2018 Br J Anaesth2018Oxygen metabolism in malignant hyperthermia susceptible skeletal muscle and the effects of static halothane exposure.
Boyle 2017 MiP20172017
John Boyle
Type 2 diabetes causes systemic skeletal muscle complex I mitochondrial dysfunction in chronic heart failure patients.
Boyle 2015 Abstract MiP20152015Kv1.3 channels in mitochondria: Are they important in cellular proliferation?
Houghton 2014 Abstract MiP20142014The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.

Participated at