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CDGSH iron-sulfur domain proteins
Description
The CDGSH iron-sulfur domain (CISDs) family of proteins uniquely ligate labile 2Fe-2S clusters with a 3Cys-1His motif. CISD1 and CISD3 have been demonstrated to localize to the outer mitochondrial membrane and mitochondrial matrix respectively, however their relationship to mitochondrial physiology remains ill-defined [1]. The best characterized member of the CISD family, CISD1, has been demonstrated to be involved in respiratory capacity, iron homeostasis, and ROS regulation
Abbreviation: CISD proteins
Reference: in progress #Wiley et al. 2007
MitoPedia concepts:
MiP concept
- entry by Robert Skolik