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Gnaiger 2017 Abstract MitoEAGLE Barcelona

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COST Action MITOEAGLE

Quality first: a paradigm shift in mt-respiratory control towards global connection.

Link:

Gnaiger E (2017)

Event: MITOEAGLE Barcelona 2017

COST Action MITOEAGLE

Few fields of basic science have experienced a reputation of fierce competition comparable to classical bioenergetics. Research investments are, however, more efficiently spent with superior outcomes and more reliable results when establishing a spirit of mentorship and collaboration across research groups, nationalities and continents. Postulates for the improvement of science have to consider the broad range from individual research careers - including the completion of PhD studies, job opportunities and funding opitons - to translational benefits for the society at large. Despite or as a consequence of the present boost of on-line journals, the email-flood and digital data overflow, the outdated vocabulary of present science indicates that a strong paradigm shift is required from conventional 'papers' (all of which should be Open Access) to structured data bases (all of which should be monitored with a responsible approach of Open Science).

(1) Concern for clarity of concepts and consistency of nomenclature is a signature of the quality of a research area across its specialisations, aimed at facilitation in teaching and translational communication [1].

(2) Harmonization of experimental procedures (protocols) is a basic requirement to increase the robustness of information and knowledge, to enable crosslinking data between different but comparable studies.

(3) Publicly deposited protocols should mark the transition from open explorative studies to research targeted at hypothesis testing. Experimental optimization of protocols including negative results should be made publicly available at an early time point. This can be easily achieved by a Preprint publication, which secures priority of authorship with citation options, opens the stage for non-anonymous review by the research community, and does not prevent final publication in a peer-reviewed journal [2-4].

(4) Any specific research field stais alert of current trends by contributing to the larger framework of scientific innovations, for instance by collectively supporting the transformation of from subscription to Open Access publishing [5,6].

(5) Open Science requests Open Access to the raw data of every publication. A dedicated knowledge management system has to be developed towards generating a rigorously monitored database on mitochondrial respiratory function.


O2k-Network Lab: AT Innsbruck Gnaiger E


Labels: MiParea: Respiration, mt-Awareness 







Affiliations

Gnaiger E(1,2)
  1. Dept Visceral, Transplant and Thoracic Surgery, Daniel Swarovski Research Laboratory, Medical University Innsbruck, Austria
  2. OROBOROS INSTRUMENTS, Innsbruck, Austria


Support

K-Regio project MitoFit. European Union Framework Programme Horizon 2020 COST Action CA15203 MITOEAGLE


References

  1. MITOEAGLE: Respiratory states
  2. Vale RD (2015) Accelerating scientific publication in biology. Proc Natl Acad Sci U S A 112:13439-46. - »Bioblast link«
  3. Berg JM et al (2016) Preprints for the life sciences. Science 352:899-901. - »Bioblast link«
  4. Preprints for Gentle Science
  5. https://oa2020.org/ - OA2020 Initiative for the large-scale transition to open access.
  6. Gentle_Science#Open_Science Open Science