Difference between revisions of "Linearity"
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|abbr= | |abbr=n.a. | ||
|description='''Linearity''' is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the [[Beer-Lambert law]] for [[absorbance]] alone, but deviations occur in [[scattering]] media. It is also a property of [[fluorescence]], but a [[fluorophore]] may not exhibit linearity, particularly over a large range of concentrations. | |description='''Linearity''' is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the [[Beer-Lambert law]] for [[absorbance]] alone, but deviations occur in [[scattering]] media. It is also a property of [[fluorescence]], but a [[fluorophore]] may not exhibit linearity, particularly over a large range of concentrations. | ||
|info=Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp. | |info=Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp. | ||
Revision as of 21:20, 24 November 2011
- high-resolution terminology - matching measurements at high-resolution
Linearity
Description
Linearity is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the Beer-Lambert law for absorbance alone, but deviations occur in scattering media. It is also a property of fluorescence, but a fluorophore may not exhibit linearity, particularly over a large range of concentrations.
Abbreviation: n.a.
Reference: Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp.
MitoPedia methods:
Fluorometry,
Spectrophotometry
