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{{Abstract
{{Abstract
|title=Meissner B, Gnaiger E (2012) ''Open Innovation'' Mitochondr Physiol Network 17.12.
|title=Meissner B, Gnaiger E (2012) ''Open Innovation''. Mitochondr Physiol Network 17.12.
|info=[[MiPNet17.12 Bioblast 2012|MiPNet17.12 Bioblast 2012 - Open Access]]
|info=[[MiPNet17.12 Bioblast 2012|MiPNet17.12 Bioblast 2012 - Open Access]]
|authors=Meissner B, Gnaiger E
|authors=Meissner B, Gnaiger E
|year=2012
|year=2012
|event=[[Bioblast 2012]]
|event=[[Bioblast 2012]]
|abstract=Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. customers that are – or might be – interested in the application of this new idea. The best way to ensure that an innovation has its market is to keep innovation “open” – by giving constant feedback to the customers and receiving it from them. The company OROBOROS INSTRUMENTS Corp. implements this notion with its company logo: the Ouroboros. The feed-back process of the dragon eating its own tail symbolizes immortality and can be translated into a successful economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run „healthier“.
|abstract=[[File:IMG 6091.jpg|right|200px|Barbara Meissner]]
Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. consumers that are interested in the application of the new goods. Many innovations in science are marketed within a highly specialized user group. A successful strategy to gaining strength in such a market is ''open innovation'': complementing feedforward to the customers by explicitly opening the system for feedback from the users. The company Oroboros Instruments Corp. implements this notion with its company logo: the Ouroboros. The feedback process of the dragon feeding from its tail symbolizes immortality and can be translated into a successful scientific and economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run ''healthier''.


Tools for giving and receiving feedback are on the one hand the highly valued workshops given by Prof. Erich Gnaiger, as well as his team and guest tutors – international experts in the field of mitochondrial physiology. On the other hand the Wiki-based webpage Bioblast is intended to educate and assist not only the users of the Oxygraph-2k, but anyone who is interested in learning about the complexity of our cells internal power units. All discussions are openly shared and through the questions of our valued customers, as well as the process of “troubleshooting” and active co-operation we gain knowledge on how to improve existing technologies and develop new ones.
Tools engaged by Oroboros Instruments for giving and receiving feedback are (i) the highly valued O2k-Workshops; attaining a cooperation of the O2k-Team with invited guest tutors – international experts in the field of mitochondrial physiology - and the participants - ranging from full professors to undergraduate students. (ii) Organization of and participation in international conferences and summer schools with high-level person-to-person scientific interactions. (iii) The Wiki-based webpage Bioblast is intended to assist not only the users of the Oxygraph-2k, but is open to the community interested in learning about the complexity of the powerhouses of our cells. Discussions are openly shared world-wide. Questions of our customers relate to scientific topics and to instrumental ''troubleshooting''. By active co-operation our scientific and technical team gains knowledge on how to improve present standards achieved in the applications of [[high-resolution respirometry]], how the available technologies can be optimized and which innovations may meet upcoming demands.


In a current project that is co-financed by the „Standortagentur Tirol“, we aim at answering the question on „How to express in order to quantitatively compare respirometric data?“. Even among experts, the field of mitochondrial physiology is regarded as „complex“. Unfortunately, this inherent complexity is not facilitated by current literature and textbooks. Not only is there a divergence with regard to defining  terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on a mitochondrial marker protein [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms – it is clear that we need a golden standard as to how results should be conveyed.
In November 2012 the Bioblast Wiki had been accessed more than 100.000 times and more than 870 peer-reviewed publications are listed on our website as O2k-Publications. Currently, 233 leading research teams from 36 countries have joined as MiPNet Reference laboratories for [[HRR]].
 
The Bioblast wiki is not (yet) used actively for various reasons that provide divergent scenarios for the future. Either the users regard the wiki as a top-down service to be maintained by the company and made available to passive users, or a bottom-up approach will gradually develop by active participation of a MitoPedia community.
# [http://www.scopus.com/record/display.url?eid=2-s2.0-67349278292&origin=inward&txGid=2T4GtLO0DGmH0CKKHuBVK-y%3a2 van de Vrande V , de Jong JPJ , Vanhaverbeke W , de Rochemont M (2009) Open innovation in SMEs: Trends, motives and management challenges. Technovation 29: 423-437.]
|keywords=''Open Innovation'', Feedback, Respiratory flux
# [[ |Gnaiger E. Isolated mitochondria or permeabilized tissues and cells. Mitochondr Physiol Network 11.05.]]
|mipnetlab=AT Innsbruck Oroboros ,
|mipnetlab=AT Innsbruck OROBOROS,  
|journal=Mitochondr Physiol Network
|journal=Mitochondr Physiol Network
|articletype=Abstract
|articletype=Abstract
Line 29: Line 29:
Barbara Meissner (1), Erich Gnaiger (1, 2)
Barbara Meissner (1), Erich Gnaiger (1, 2)


(1) OROBOROS INSTRUMENTS, Innsbruck, Austria; Email: [email protected]
(1) Oroboros Instruments, Innsbruck, Austria; Email: [email protected]


(2) D. Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Austria
(2) D. Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Austria
== References ==
# [http://www.scopus.com/record/display.url?eid=2-s2.0-67349278292&origin=inward&txGid=2T4GtLO0DGmH0CKKHuBVK-y%3a2 van de Vrande V , de Jong JPJ , Vanhaverbeke W , de Rochemont M (2009) Open innovation in SMEs: Trends, motives and management challenges. Technovation 29: 423-437.]
== Work in progress ==
In a current project that is co-financed by the ''Standortagentur Tirol'' [1], we aim at answering the question on ''How to express in order to quantitatively compare respirometric data?''. Even among experts, the field of mitochondrial physiology is regarded as ''complex''. Not only is there a divergence with regard to defining terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on mitochondrial markers [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms, methods are needed for quantitative determination of oxygen consumption, standardized conditions are important (such as incubation media, experimental temperature, titration regimes), and practical standards should be improved on quantification and normalization of respirometric data.
# [[Open Innovation|Standortagentur Tirol - InnovationsassistentIn - Open Innovation]]
# [[Gnaiger 2009 Int J Biochem Cell Biol|Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41: 1837-1845.]]


== Help ==
== Help ==
* [[Abstracts help]]
* [[MitoPedia: Terms and abbreviations]]
* [[MitoPedia Glossary: Terms and abbreviations]]

Latest revision as of 10:40, 23 January 2019

Meissner B, Gnaiger E (2012) Open Innovation. Mitochondr Physiol Network 17.12.

Link: MiPNet17.12 Bioblast 2012 - Open Access

Meissner B, Gnaiger E (2012)

Event: Bioblast 2012

Barbara Meissner

Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. consumers that are interested in the application of the new goods. Many innovations in science are marketed within a highly specialized user group. A successful strategy to gaining strength in such a market is open innovation: complementing feedforward to the customers by explicitly opening the system for feedback from the users. The company Oroboros Instruments Corp. implements this notion with its company logo: the Ouroboros. The feedback process of the dragon feeding from its tail symbolizes immortality and can be translated into a successful scientific and economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run healthier.

Tools engaged by Oroboros Instruments for giving and receiving feedback are (i) the highly valued O2k-Workshops; attaining a cooperation of the O2k-Team with invited guest tutors – international experts in the field of mitochondrial physiology - and the participants - ranging from full professors to undergraduate students. (ii) Organization of and participation in international conferences and summer schools with high-level person-to-person scientific interactions. (iii) The Wiki-based webpage Bioblast is intended to assist not only the users of the Oxygraph-2k, but is open to the community interested in learning about the complexity of the powerhouses of our cells. Discussions are openly shared world-wide. Questions of our customers relate to scientific topics and to instrumental troubleshooting. By active co-operation our scientific and technical team gains knowledge on how to improve present standards achieved in the applications of high-resolution respirometry, how the available technologies can be optimized and which innovations may meet upcoming demands.

In November 2012 the Bioblast Wiki had been accessed more than 100.000 times and more than 870 peer-reviewed publications are listed on our website as O2k-Publications. Currently, 233 leading research teams from 36 countries have joined as MiPNet Reference laboratories for HRR. The Bioblast wiki is not (yet) used actively for various reasons that provide divergent scenarios for the future. Either the users regard the wiki as a top-down service to be maintained by the company and made available to passive users, or a bottom-up approach will gradually develop by active participation of a MitoPedia community.

Keywords: Open Innovation, Feedback, Respiratory flux

O2k-Network Lab: AT Innsbruck Oroboros


Labels:





HRR: Theory 




Affiliations and author contributions

Barbara Meissner (1), Erich Gnaiger (1, 2)

(1) Oroboros Instruments, Innsbruck, Austria; Email: [email protected]

(2) D. Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Austria

References

  1. van de Vrande V , de Jong JPJ , Vanhaverbeke W , de Rochemont M (2009) Open innovation in SMEs: Trends, motives and management challenges. Technovation 29: 423-437.

Work in progress

In a current project that is co-financed by the Standortagentur Tirol [1], we aim at answering the question on How to express in order to quantitatively compare respirometric data?. Even among experts, the field of mitochondrial physiology is regarded as complex. Not only is there a divergence with regard to defining terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on mitochondrial markers [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms, methods are needed for quantitative determination of oxygen consumption, standardized conditions are important (such as incubation media, experimental temperature, titration regimes), and practical standards should be improved on quantification and normalization of respirometric data.

  1. Standortagentur Tirol - InnovationsassistentIn - Open Innovation
  2. Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int J Biochem Cell Biol 41: 1837-1845.

Help