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Difference between revisions of "Meissner 2012 Abstract Bioblast"

From Bioblast
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|event=[[Bioblast 2012]]
|event=[[Bioblast 2012]]
|abstract=[[File:IMG 6091.jpg|right|200px|Barbara Meissner]]
|abstract=[[File:IMG 6091.jpg|right|200px|Barbara Meissner]]
Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. customers that are – or might be – interested in the application of this new idea. The best way to ensure that an innovation has its market is to keep innovation ''open'' – by giving constant feedback to the customers and receiving it from them. The company OROBOROS INSTRUMENTS Corp. implements this notion with its company logo: the Ouroboros. The feed-back process of the dragon eating its own tail symbolizes immortality and can be translated into a successful economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run ''healthier''.
Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. consumers that are interested in the application of the new goods. Many innovations in science are marketed within a highly specialized user group. A successful strategy to gaining strength in such a market is ''open innovation'': complementing feedforward to the customers by explicitly opening the system for feedback from the users. The company OROBOROS INSTRUMENTS Corp. implements this notion with its company logo: the Ouroboros. The feedback process of the dragon feeding from its tail symbolizes immortality and can be translated into a successful scientific and economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run ''healthier''.


Tools for giving and receiving feedback are on the one hand the highly valued workshops given by Prof. Erich Gnaiger, as well as his team and guest tutors – international experts in the field of mitochondrial physiology. On the other hand the Wiki-based webpage Bioblast is intended to educate and assist not only the users of the Oxygraph-2k, but anyone who is interested in learning about the complexity of our cells internal power units. All discussions are openly shared and through the questions of our valued customers, as well as the process of ''troubleshooting'' and active co-operation we gain knowledge on how to improve existing technologies and develop new ones.
Tools for giving and receiving feedback are (i) the highly valued O2k-Workshops, developing a cooperation of the O2k-Team with invited guest tutors – international experts in the field of mitochondrial physiology - and the participants - ranging from full professors to undergraduate students. (ii) Organization of and participation in international conferences with direct interactions. (iii) The Wiki-based webpage Bioblast is intended to educate and assist not only the users of the Oxygraph-2k, but anyone who is interested in learning about the complexity of the powerhouses of our cells. All discussions are openly shared and through the questions of our customers, as well as the process of ''troubleshooting'' and active co-operation we gain knowledge on how to improve existing technologies and develop new ones.


In a current project that is co-financed by the ''Standortagentur Tirol'', we aim at answering the question on ''How to express in order to quantitatively compare respirometric data?''. Even among experts, the field of mitochondrial physiology is regarded as ''complex''. Unfortunately, this inherent complexity is not facilitated by current literature and textbooks. Not only is there a divergence with regard to defining terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on a mitochondrial marker protein [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms – it is clear that we need a golden standard as to how results should be conveyed.
In a current project that is co-financed by the ''Standortagentur Tirol'', we aim at answering the question on ''How to express in order to quantitatively compare respirometric data?''. Even among experts, the field of mitochondrial physiology is regarded as ''complex''. Unfortunately, this inherent complexity is not facilitated by current literature and textbooks. Not only is there a divergence with regard to defining terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on a mitochondrial marker protein [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms – it is clear that we need a golden standard as to how results should be conveyed.

Revision as of 20:14, 28 November 2012

Meissner B, Gnaiger E (2012) Open Innovation. Mitochondr Physiol Network 17.12.

Link: MiPNet17.12 Bioblast 2012 - Open Access

Meissner B, Gnaiger E (2012)

Event: Bioblast 2012

Barbara Meissner

Innovation is the industrial realization of a new idea – be it a new product, production process or service. Any innovation is only useful if there is a market, i.e. consumers that are interested in the application of the new goods. Many innovations in science are marketed within a highly specialized user group. A successful strategy to gaining strength in such a market is open innovation: complementing feedforward to the customers by explicitly opening the system for feedback from the users. The company OROBOROS INSTRUMENTS Corp. implements this notion with its company logo: the Ouroboros. The feedback process of the dragon feeding from its tail symbolizes immortality and can be translated into a successful scientific and economic strategy. A study by van de Vrande in 2009 [1] shows that SMEs (small and medium-sized enterprises) which are willing to share internal knowledge manage to find alternative pathways to markets – making them in the long run healthier.

Tools for giving and receiving feedback are (i) the highly valued O2k-Workshops, developing a cooperation of the O2k-Team with invited guest tutors – international experts in the field of mitochondrial physiology - and the participants - ranging from full professors to undergraduate students. (ii) Organization of and participation in international conferences with direct interactions. (iii) The Wiki-based webpage Bioblast is intended to educate and assist not only the users of the Oxygraph-2k, but anyone who is interested in learning about the complexity of the powerhouses of our cells. All discussions are openly shared and through the questions of our customers, as well as the process of troubleshooting and active co-operation we gain knowledge on how to improve existing technologies and develop new ones.

In a current project that is co-financed by the Standortagentur Tirol, we aim at answering the question on How to express in order to quantitatively compare respirometric data?. Even among experts, the field of mitochondrial physiology is regarded as complex. Unfortunately, this inherent complexity is not facilitated by current literature and textbooks. Not only is there a divergence with regard to defining terms, but also when it comes to presentation of respirometric results. Respiratory flux is frequently related to tissue wet weight or million cells, or respiratory flux is quantified based on a mitochondrial marker protein [2]. To allow comparison of different experiments in different cells – as well as different tissues and organisms – it is clear that we need a golden standard as to how results should be conveyed.

  1. van de Vrande V , de Jong JPJ , Vanhaverbeke W , de Rochemont M (2009) Open innovation in SMEs: Trends, motives and management challenges. Technovation 29: 423-437.
  2. Gnaiger E. Isolated mitochondria or permeabilized tissues and cells. Mitochondr Physiol Network 11.05.
  3. Standortagentur Tirol - InnovationsassistentIn - Open Innovation

β€’ Keywords: Open Innovation, Feedback, Respiratory flux

β€’ O2k-Network Lab: AT Innsbruck OROBOROS


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HRR: Theory 




Affiliations and author contributions

Barbara Meissner (1), Erich Gnaiger (1, 2)

(1) OROBOROS INSTRUMENTS, Innsbruck, Austria; Email: [email protected]

(2) D. Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Austria

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