View source for MiPschool 2012 Cambridge UK Programme

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==MiP''summer'' Programme==

::::FEBS workshop & MiP''summer School'' on Mitochondria at Cambridge 2012

::::*Final programme with poster presentations - [http://www.mitophysiology.org/fileadmin/user_upload/MiP/MiP''summer''2012_Programme.pdf download pdf]
::::*Poster presentations

{|class='wikitable'
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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"|'''Saturday, 7th July Arrival'''
|-
|17:00
|Bridgetower room
|Registration
|-
|20:00 - 20:15 
|Lecture theatre
|Welcome to Cambridge 
|-
|20:15 - 21:15 
|Cleveland
|Chuck Hoppel - Mitochondrial physiology and functional testing in diagnosis of mitochondrial disease (Lecture theatre)
|-
|21:15 
|Terrace room
|Reception 
|}

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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Sunday, 8th July'''
|-
|09:00
|Graham Storey room
|Mitochondrial structure and respiratory function session
|-
|09:00 - 09:30
|Innsbruck
|Erich Gnaiger - Mitochondrial respiration: in vitro to in vivo
|-
|09:30 - 10:00
|Bordeaux
|Rodrigue Rossignol - Mitochondrial structure, fission and networks
|-
|10:00 - 10:15
|Baton Rouge
|Steve Hand - Protein targeting and translocation into mitochondria
|-
|10:15 - 10:30
|
|Discussion
|-
|10:30
|Dining Hall
|Coffee break 
|-
|11:00 - 11:15
|Gothenburg
|Shijun Xu - Mitochondrial dynamics at single cell level
|-
|11:15 - 11:30
|NIH
|Kel Sheldon - VDAC blockage by tubulin is the missing link of mitochondrial respiration control
|-
|11:30 - 11:45
|Nijmegen
|Marleen Forkink - Inhibiting mitochondrial Complex I or Complex III differentially affects mitochondrial physiology
|-
|11:45 - 12:00
|Granada
|Laura García Corzo - A new insight about molecular aspects of CoQ deficiency
|-
|12:00 - 12:15
|Granada
|Marta Luna-Sánchez - CoQ deficiency: molecular and pathophysiology consequences
|-
|12:15 - 12:30
|
|Discussion
|-
|12:30
|Dining Hall
|Lunch  
|-
|13:30
|Graham Storey room
|Experimental methods session 
|-
|13:30 - 13:50
|Kaunas
|Vilmante Borutaite - How to isolate mitochondria
|-
|13:50 - 14:10
|Bordeaux
|Rodrigue Rossignol - How to measure morphology, fusion/fission
|-
|14:10 - 14:30
|Regensburg
|Kathrin Renner - How to measure respiration & membrane potential
|-
|14:30 - 14:50
|Innsbruck
|Erich Gnaiger - How to express respiratory states - www.bioblast.at
|-
|14:50 - 15:10
|Cleveland
|Chuck Hoppel - How to diagnose mitochondrial disease
|-
|15:10 - 15:30
|Cambridge
|Aviva Tolkovsky - How to measure cell death and mitophagy
|-
|15:30 - 15:50
|Cambridge
|Mike Murphy - How to measure ROS
|-
|15:50 - 16:00
|
|Discussion
|-
|16:00
|Dining Hall
|Tea break 
|-
|16:30
|Graham Storey room
|Mitochondrial coupling, thermogenesis & obesity session 
|-
|16:30 - 16:45
|Cambridge
|Guy Brown - Mitochondrial energy production
|-
|16:45 - 17:00
|Ottawa
|Mary Ellen Harper - Variable mitochondrial oxidative phosphorylation efficiency and its implications for obesity
|-
|17:00 - 17:15
|Stockholm
|Maria Holmström - Tissue-specific effects of leptin treatment on mitochondrial function in obese leptin-deficient (ob/ob) mice
|-
|17:15 - 17:30
|Namur
|Thierry Arnould - Mitochondrial uncoupling induces modifications of glucose metabolism and microRNA expression in 3T3-L1 adipocytes
|-
|17:30 - 17:45
|Rio de Janeiro
|Erika Cortez - Mitochondrial oxidative metabolism impairment in bone marrow mononuclear cells of obese mice
|-
|17:45 - 18:00
|Stockholm
|Anastasia Kalinovich - The effects of the mitochondria-targeted cationic uncoupler C12TPP on brown adipose tissue mitochondria, cells & mice
|-
|18:00 - 19:00
|
|Discussion
|-
|19:00
|Dining Hall
|Dinner 
|-
|21:00
|
|Evening tour of Cambridge & its pubs
|-
|}

{|class='wikitable'
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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Monday, 9th July'''
|-
|09:00
|Graham Storey room
|Mitophagy, neurons and neurodegenerative disease session 
|-
|09:00 - 09:30
|Cambridge
|Aviva Tolkovsky - Mitophagy and neurodegeneration
|-
|09:30 - 10:00
|Kaunas
|Vilmante Borutaite - Mitochondria in ischaemic & neurodegenerative disease
|-
|10:00 - 10:15
|Canada
|Subir Roy Chowdhury - Neurodegeneration in diabetes is linked to impaired AMPK signaling and mitochondrial dysfunction
|-
|10:15 - 10:30
|
|Discussion
|-
|10:30
|Dining Hall
|Coffee 
|-
|11:00 - 11:15
|Leicester
|Ana Carina Costa - Mitochondrial chaperone Trap1 interacts genetically with Pink1 in Drosophila
|-
|11:15 - 11:30
|Frankfurt
|Carola Schiller - Mitochondrial dysfunction in SY5Y cells moderately expressing human ß-amyloid
|-
|11:30 - 11:45
|Oxford
|Joanna Poulton - Severe OPA1 mutations dysregulate mitophagy and disorganise the location of mitochondria in patients with OPA1 plus
|-
|11:45 - 12:15
|
|Discussion
|-
|12:30
|Dining Hall
|Lunch - or MiP Society Board Meeting (Bridgetower room)
|-
|13:30 - 15:00
|meet outside Graham Storey room
|Walk to Grantchester 
|-
|15:00 - 16:00
|in Orchard Tea Gardens
|Special interest discussion sessions or The Green Man - Structure & dynamics or Mitophagy & Neurodegeneration or Obesity & Coupling or Respiratory function
|-
|16:00 - 17:00
|
|Walk back to Cambridge
|-
|17:30
|Graham Storey room
|Reactive oxygen species session 
|-
|17:30 - 18:00
|Cambridge MBU
|Michael Murphy - Targeting bioactive molecules to mitochondria
|-
|18:00 - 18:15
|Denver
|Heather Wilkins - Dicarboxylate carrier-mediated transport of glutathione into mitochondria determines neuronal susceptibility to oxidative and nitrosative stress
|-
|18:15 - 18:30
|Rome
|Maria Chiara Magnifico - Cell bioenergetics, nitric oxide and melatonin 
|-
|18:30 - 18:45
|Frankfurt
|Stephanie Hagl - Herbal antioxidants induce mitogenesis and improve mitochondrial function in PC12 cells
|-
|18:45 - 19:00
|Ottawa
|Ryan Mailloux - Glutaredoxin-2 and glutathionylation in the regulation of mitochondrial energetics in mice
|-
|19:00 - 19:30
|
|Discussion
|-
|19:30
|Dining Hall
|Dinner 
|-
|21:00 - 22:00
|Bar & Crescent room
|Poster session 
|-
|}

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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Tuesday, 10th July''' 
|-
|09:00
|Graham Storey room
|MRC Mitochondrial Biology Unit 
|-
|09:00 - 09:40
|Cambridge MBU
|Sir John Walker - The ATP synthase
|-
|09:40 - 10:20
|Cambridge MBU
|Leonid Sazonov - Mitochondrial Complex I
|-
|10:20
|Dining Hall
|Coffee break 
|-
|10:50 - 11:30
|Cambridge MBU
|Edmund Kunji - Mitochondrial transport proteins
|-
|11:30 - 12:10
|Cambridge MBU
|Michal Minczuk - Posttranscriptional regulation of mtDNA expression
|-
|12:10 - 12:50
|Cambridge MBU
|Antonella Spinazzola - Mitochondrial nucleiods and biogenesis
|-
|13:00
|Dining Hall
|Lunch 
|-
|14:00
|Graham Storey room
|Hypoxia, stress and exercise session 
|-
|14:00 - 14:30
|Baton Rouge
|Steve Hand - Mitochondrial function in an invertebrate extremophile
|-
|14:30 - 15:00
|Cambridge
|Andrew Murray - Mitochondria in hypoxia, exercise and altitude
|-
|15:00 - 15:15
|Munich
|Matthias Elstner - Life is not a sprint, it's a marathon: the metabolic gene expression footprint of human muscle fibres
|-
|15:15 - 15:30
|Melbourne
|Cesare Granata - Mitochondrial adaptations to different training stimuli: the remarkable plasticity of skeletal muscle oxidative capacity
|-
|15:30 - 15:45
|Prague
|Dita Kasparova - Expression of mitochondrial creatine kinase and hexokinase is amplified in the rat heart adapted to chronic hypoxia
|-
|15:45 - 16:15
|
|Discussion
|-
|16:15
|Dining Hall
|Tea break 
|-
|17:15 - 19:15
|Graham Storey room
|Meet the PI session - 10 min 1 to 1 with the PIs of your choice
|-
|19:30
|Dining Hall
|Dinner
|-
|21:00 - 22:00
|Bar & Crescent room
|Poster session 
|-
|}


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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Wednesday, 11th July''' 
|-
|09:00
|Graham Storey room
|Cancer, Sepsis & Immunity session 
|-
|09:00 - 09:30
|Bordeaux 
|Rodrigue Rossignol - Mitochondria and cancer 
|-
|09:30 - 10:00
|Cambridge
|Elizabeth Murchison - The devil's mitochondria: biology and evolution of transmissible cancers
|-
|10:00 - 10:15
|Prague
|Martina Bajzíková - Mitochondrial targeting of vitamin E succinate enhances its anti-cancer activity via mitochondrial Complex II 
|-
|10:15 - 10:30
|
|Discussion
|-
|10:30
|Dining Hall
|Coffee break 
|-
|11:00 - 11:30
|London
|Mervyn Singer - Mitochondria and sepsis 
|-
|11:30 - 11:45
|Basel
|Marco Fischer - Metabolic profiles of human naïve and memory CD8+ T cells
|-
|11:45 - 12:15
|
|Discussion
|-
|12:30
|Dining Hall
|Lunch 
|-
|13:30 - 14:30
|Graham Storey room
|Special interest group discussion sessions - Modelling & regulation or Pathology or Reactive Oxygen Species or Hypoxia & Exercise & Mitochondrial DNA & disease or Cell death & the heart
|-
|14:30 - 15:30
|
|Punting session 
|-
|15:30
|Dining Hall
|Tea break 
|-
|16:00
|Graham Storey room
|Mitochondrial modelling & regulation of energy metabolism session 
|-
|16:00 - 16:30
|Krakow
|Bernard Korzeniewski - Computer modelling of metabolic systems
|-
|16:30 - 17:00
|Cambridge MBU
|Alan Robinson - Modelling the metabolism of the mitochondrion
|-
|17:00 - 17:30
|Essex
|Chris Cooper - Cytochrome oxidase and its modelling 
|-
|17:30 - 17:45
|Barcelona
|Vitaly Selivanov - Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis
|-
|17:45 - 18:00
|Singapore
|Chong Kiat Goo - PI3K/Akt signaling enhances mitochondrial respiratory capacity through 4E-BP1
|-
|18:00 - 18:15
|Copenhagen
|Robert Boushel - Inhibition of skeletal muscle ATPase activity alters mitochondrial substrate and adenylate control of OXPHOS, uncoupling
|-
|18:15 - 18:30
|Bordeaux
|Philippe Diolez - From in vivo to in vitro: top-down control analyses of mitochondrial bioenergetics impairment in aged rat gastrocnemius muscle
|-
|18:30 - 19:00
|
|Discussion
|-
|19:30
|Dining Hall
|Dinner 
|-
|21:00 - 22:00
|Bar & Crescent room
|Poster session 
|-
|}

{|class='wikitable'
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|style="width: 10em"|
|style="width: 15em"|
|style="width: 60em"| '''Thursday, 12th July'''  
|-
|09:00
|Graham Storey room
|Mitochondrial cell death, pathology & the heart session 
|-
|09:00 - 09:15
|Cambridge
|Guy Brown - Cell death pathways
|-
|09:15 - 09:45
|London
|Michael Duchen - Mitochondrial pathology 
|-
|09:45 - 10:15
|Bristol
|Andrew Halestrap - Mechanisms regulating ROS production and the permeability transition pore in ischaemia/reperfusion injury of the heart
|-
|10:15 - 10:45
|
|Discussion
|-
|10:45
|
|Coffee break
|-
|11:15 - 11:30
|Riga, Latvia
|Marina Makrecka - Reduced availability of L-carnitine protects cardiac mitochondria against fatty acid-induced stress
|-
|11:30 - 11:45
|Prague, Czeck
|Magdaléna Vondrusová - The role of mitochondrial supercomplexes in apoptosis induction by mitochondria-targeted agents
|-
|11:45 - 12:00
|Prague
|Petra Arnostova - Comparison of hexokinase expression in the left and right ventricle of male Wistar rats
|-
|12:10 - 12:30
|
|Discussion
|-
|12:30
|Dining Hall
|Lunch  
|-
|13:30 - 14:30
|
|Punting session
|-
|14:30 - 15:30
|Graham Storey room
|The Great Debate session - The future of mitochondrial research
|-
|15:30
|Dining Hall
|Tea break 
|-
|16:00
|Graham Storey room
|Mitochondrial evolution, DNA & disease session 
|-
|16:00 - 16:30
|London
|Nick Lane - Mitochondria in the evolution of complex life
|-
|16:30 - 17:00
|Tokyo
|Masashi Tanaka - Rapid genetic diagnosis and pyruvate therapy for mitochondrial diseases
|-
|17:00 - 17:15
|Taiwan
|Chin San Liu - Functional recovery in human cells harboring MERRF A8344G mutation of mitochondrial DNA via peptide-mediated mitochondrial delivery
|-
|17:15 - 17:30
|Bristol
|Sarah Miles - Effect of DNA lesions on transcription by human mitochondrial RNA polymerase
|-
|-17:30 - 18:00
|
|Discussion
|-
|18:00 - 18:30
|Graham Storey room
|Summary - feedback - evaluation 
|-
|18:30 - 19:30
|Graham Storey room &/or outside
|Reception & MiPArt exhibition 
|-
|19:30
|Dining Hall
|MiP ''Summer'' Dinner 
|-
|21:00
|Dining Hall
|MiP special lecture: Chris Cooper - The Mitochondrial Olympics 
|-
|}

::::'''Friday, 13th July Departure'''




==MiP''summer'' Posters==

 
::::1. Chong Kiat Goo, HY Lim, and KP Wong
::::An improved polarographic measurement for cytochrome c oxidase activity


::::2. Periyasamy Govindaraj, Nahid A Khan, A Vanniarajan, Bindu Hooda, Madhu Khullar, Deepa Selvi Rani, Dharma Rakshak, K Premkumar, K Thangaraj
::::Mitochondrial DNA variations in Indian cardiomyopathy patients
	

::::3. Emmanouela Kallergi, M Andreadaki, P Kritsiligkou, E Lionaki, N Katrakili, C Pozidis, K Tokatlidis
::::Bimodal interaction of sulfhydryl oxidase Erv1 with Mia40 in yeast mitochondria


::::4. Carsten Krischek, J Popp, M Wicke, G Klein
::::Mitochondrial respiratory activity in longissimus muscle samples of pigs in relation to the post mortal pH value reduction


::::5. Luis Carlos López, L García-Corzo, M Luna-Sánchez, JA Santos, C Doerrier, A López, G Escames, D Acuña-Castroviejo
::::Understanding the mammalian CoQ biosynthesis and the genotype-phenotype relationship in CoQ deficiency syndrome


::::6. Katalin Módis, Ciro Coletta, Andreas Papapetropoulos, Csaba Szabo
::::Cooperative interactions of H2S and Krebs cycle-derived electron donors in maintenance of mitochondrial electron transport and cellular bioenergetics


::::7. Janine Pfaff, S Gispert, G Auburger, M Jendrach
::::The fission factor MTP18 has a putative role in Parkinson’s disease


::::8. Alexandre Prola, R Ventura-Clapier, C Lemaire
::::SIRT1 regulates endoplasmic reticulum stress-induced apoptosis in H9c2 cardiac cells


::::9. A Brianne Thrush, R Boushel, Dent R, McPherson R, ME Harper
::::Mitochondrial flux control in human rectus abdominus muscle of obese patients


::::10. A Brianne Thrush, R Boushel, ME Harper
::::Inhibition of skeletal muscle ATPase activity alters mitochondrial substrate and adenylate control of OXPHOS, uncoupling and COX activity


::::11. Lisa Trollope, HJ Mortiboys, M Rattray, O Bandmann
::::Epigenetics and mitochondrial dysfunction in Huntington’s disease


::::12. Tsygankova Polina, Zakharova EYu, Itkis YuS, Mikhailova SV, Rudenskaya GE, Dadali EL, Nikolaeva EA, Pichkur NA
::::Genetics + biochemistry. How to improve diagnostic of early forms of mitochondrial respiratory chain diseases? 


::::13. Emma Yu, JR Mercer, N Figg, L Baker, J Harrison, MR Bennett
::::Mitochondrial DNA damage, dysfunction and atherosclerosis