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Revision as of 11:09, 17 October 2018

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MiPschool Tromso-Bergen 2018


Publications in the MiPMap
COST Action MitoEAGLE
MiPsociety

Tromso-Bergen, NO. 2018 Oct 20-24, 11th MitoEAGLE Training School - MiPschool 2018. From basics of mitochondrial physiology to cardiovascular health and disease.

Âť Mitochondrial Physiology Society

Mitochondrial Physiology Society (2018-10-20) MitoGlobal

Abstract: MiPschool, Tromso-Bergen, Norway 2018

University of Tromsø


Venue and accommodation

Hurtigruten
Bergen to Tromso
Norway
Impressions: Ship and Hurtigruten travel offers


Local organizer

Terje Larsen
Larsen Terje
Faculty of Health Sciences, University of Tromsø


Lecturers

Meet the expert

Programme

Topic

Programme structure

Check-in will take place on Saturday, October 20 from 21:00-23:30 pm at Skarven Bar downtown Tromsø, and on the Coastal Express on Sunday from 00:15-01:30 am. We will disembark on Wednesday, October 24 at 14:30 in Bergen.


Main topics - from basics of mitochondiral physiology to cardiovascular health and disease
  • Mitochondrial pathways: understanding the basics
  • The protonmotive force and respiratory control: Coupling states and rates
  • The protonmotive force and respiratory control: the thermokinetic basis
  1. Molecular motion in a diffusion gradient: from Fick’s law, the gas law and the van’t Hoff equation, to Einstein’s diffusion equation
  2. We do not measure gradients: from concentration and potential gradients to concentration and potential differences
  3. Electrochemical protonmotive force and chemiosmotic pressure: proton pumps and counterions
  4. Why are mitochondria small? Implications of the mitochondrial volume fraction on -200 mV, non-linear respiratory control by the protonmotive force explained by protonmotive pressure.
  • Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes - impact on cardiac E-C coupling
  • Two populations of muscle mitochondria: heart and skeletal muscle
  • OXPHOS efficiency in skeletal and cardiac muscles
  • Mitochondrial function during ischemia/reperfusion injury
  • Actomyosin contraction and the dynamics of calcium changes in cardiomyocytes
  • OXPHOS protocols: understanding the patterns
The scientific sessions consist of introductory lectures, selected abstract presentations, and discussions in small groups in an open “meet the expert” format.
Sessions E1 and E2: Meet the expert - open MitoEAGLE topics - MitoEAGLE Early Career Investigator Forum
Session E3 – Open programme lectures: Programme decisions made during and by the MitoEAGLE/MiPschool (voted from the MitoEAGLE Early Career Investigator Forum)

Sessions with abstracts for oral presentations

 A1. Mitochondrial physiology: pathways and couplingSession
Gnaiger 2018 MiPschool Tromso A1
Erich Gnaiger
Mitochondrial states and rates: 1. Electron transfer pathways and respiratory control. 2. Coupling control.
Oral
A1


 B1. Energy transfer and movement of molecules in cardiomyocytesSession
Schlattner 2018 MiPschool Tromso B1
Uwe Schlattner
Mitochondrial kinases: key players in respiratory control and energy transfer.
B1
Oral
Vendelin 2018 MiPschool Tromso B1
Marko Vendelin
Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
B1
Oral


 C1. Selected abstracts: Cardiac OXPHOSSession
Pereira 2018 MiPschool Tromso C1
Pereira Susana P
Obesity-induced mitochondrial hepatic changes during pregnancy.
Oral
C1
Goncalo Teixeira 2018 MiPschool Tromso C1
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
Oral
C1
Ma 2018 MiPschool Tromso C1
MiPsociety
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
C1
Oral


 C2. Selected abstracts: CardioprotectionSession
Jansen 2018 MiPschool Tromso C2
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
C2
Oral
Kampa 2018 MiPschool Tromso C2
Rafal Kampa
Cardioprotective flavoniods as a natural modulators of mitoBKCa channel.
C2
Oral
MartinsJD 2018 MiPschool Tromso C2
MiPsociety
Sweetheart: Cardiac consequences of fetal exposure to maternal gestational diabetes on the offspring mitochondrial function.
C2
Oral
Tuncay 2018 MiPschool Tromso C2
MiPsociety
MitoTEMPO ameliorates hyperglycemia induced mitochondrial damage in cardiomyocytes.
C2
Oral


 D1. Cardiovascular disease and mitochondrial medicineSession
Harper 2018 MiPschool Tromso D1
Mary-Ellen Harper
OXPHOS efficiency in skeletal and cardiac muscles: Proton leaks, ROS and glutathione redox.
D1
Oral
Hoppel 2018 MiPschool Tromso D1
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
D1
Oral


 A2. Mitochondrial physiology: protonmotive forceSession
Gnaiger 2018 MiPschool Tromso A2
Erich Gnaiger
The protonmotive force and respiratory control. 1. Coupling of electron transfer reactions to vectorial translocation of protons. 2. From Einstein’s diffusion equation on gradients to Fick’s law on compartments.
Oral
A2


 C3. Selected abstracts: Adipose and liver mitochondriaSession
Torp 2018 MiPschool Tromso C3
MiPsociety
Intracellular complement factor 3 in the heart – a link to metabolism?
Oral
C3
Isola 2018 MiPschool Tromso C3
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Oral
C3


 D2. Cardiac mitochondrial physiology and pathologySession
Vendelin 2018 MiPschool Tromso D2
Marko Vendelin
Modeling actomyosin contraction in the heart muscle.
D2
Oral
Hoppel 2018 MiPschool Tromso D2
Charles Hoppel
Mitochondrial function during ischemia/reperfusion injury.
D2
Oral


 C4. Selected abstracts: Mitochondrial disorders, remodeling, and degenerative diseasesSession
Crisostomo 2018 MiPschool Tromso C4
Luis Crisostomo
Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?
C4
Oral
Zdrazilova 2018 MiPschool Tromso C4
MiPsociety
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
C4
Oral
Vujacic-Mirski 2018 MiPschool Tromso C4
MiPsociety
Development of analytical assays for the detection and quantification of reactive oxygen and nitrogen species in an animal model of type 1 diabetes - ROS formation involving mitochondrial and NADPH oxidase.
C4
Oral
Musiol 2018 MiPschool Tromso C4
MiPsociety
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
C4
Oral
Bastos Sant'Anna Silva 2018 MiPschool Tromso C4
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
C4
Oral
Vella 2018 MiPschool Tromso C4
Joanna Vella
Exome analysis sheds light on mitochondrial disorders.
C4
Oral


 D3. Mitochondrial function and cardioprotectionSession
Wuest 2018 MiPschool Tromso D3
Wuest Rob
Metabolic flexibility and mitochondrial function in the diabetic heart.
D3
Oral
Boardman 2018 MiPschool Tromso D3
MiPsociety
High fat-load induces cardioprotection in hearts from obese mice.
Oral
D3


Registration and further information

The maximum number of attendees for the MiP/MitoEAGLE Training School 2018 of 65 participants is reached.
closed


MitoEAGLE
  • The MitoEAGLE network aims to improve our knowledge on mitochondrial function in health and disease related to Evolution, Age, Gender, Lifestyle and Environment. Every study of mitochondrial (mt) function and disease is faced with EAGLE as the essential background conditions characterizing the individual patient, subject, study group, species, tissue or even cell line.
Membership in the MitoEAGLE network is open to all researchers sharing an interest in mitochondrial research and medicine
Âť Join the COST Action CA15203 MITOEAGLE


MiPsociety
  • The MiPsociety is an international organization, based in Europe and operating world-wide and has become a legal body in 2011 continuing a tradition of rigorous mitochondrial bioenergetics; integrating molecular, cellular and organismic physiology and pathology.
Membership is open to all researchers
Âť MiP membership


How to get there

There are daily flights in each direction between Oslo and Tromsø, flown by SAS and Norwegian (Please note that there are only a few flights on a Saturday)
The same companies also offer some direct flights from Stockholm Arlanda, Copenhagen, and London Gatwick, but these are seasonal (so do check yourselves if these routes are operating and of interest).
Arctic Airlink also offer direct flights to Tromsø from Luleü and Oulu. The nearest train station is Narvik.
It is 3 1/2 hours’ drive from Tromsø, and it is connected to the Swedish, not the Norwegian, rail network (sj.se). There is a bus link from Narvik, but usually, the train does not meet the last bus to Tromsø.


Training school participants arriving in Tromsø before October 20th can find accommodation on the official travel guide to Tromsø (https://www.visittromso.no/en/Troms%C3%B8%20Airport), which gives you an overview of the various hotels in the city, as well as transportation from the airport to the city center, and what to do in Tromsø.
On Saturday morning (from 10:00 h), we will organize a meeting place at the UiT Campus for training school participants arriving throughout the day (information desk and temporary luggage storage).
Here, you will also have access to Internet and, if needed, a quiet spot for work. Take a taxi from the airport to the university and ask the driver to stop at the main (west) entrance of the MH building (link to map). The meeting place will keep open until 21:00 h.
In the city, luggage lockers are available on the 1st floor in the harbour terminal (link to map). These are card-operated lockers, and cost NOK 60 for a 24-hour period. Available during the terminal opening hours: 05.30-02.00 h.
The registration desk opens at 21:00 h at Skarven Bar downtown Tromsø. This will be our assembly point until the Coastal Express arrives around midnight. We will walk from the bar to the harbor terminal, which is just a couple of minutes away (link to map).

Participants and abstracts - alphabetical order

 Presentation
Alves 2018 MiPschool Tromso E2
MiPsociety
Role for mitochondria on the response of highly proliferative and invasive bladder cancer cells to the combined inhibition of mTOR and SIRT1.
Arago 2018 MiPschool Tromso
MiPsociety
No abstract.
Armand 2018 MiPschool Tromso
MiPsociety
No abstract.
Bajzikova 2018 MiPschool Tromso
MiPsociety
No abstract.
Bastos Sant'Anna Silva 2018 MiPschool Tromso C4
Ana Bastos Sant'Anna
Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.
Bello 2018 MiPschool Tromso
MiPsociety
No abstract.
Bergmeister 2018 MiPschool Tromso
Lisa Bergmeister
No abstract.
Boardman 2018 MiPschool Tromso D3
MiPsociety
High fat-load induces cardioprotection in hearts from obese mice.
Cardoso 2018 MiPschool Tromso E2
Luiza Helena Cardoso
Concomitant respiration and ATP production measurements to analyse PÂť/O2 ratios at physiological normoxia.
Crisostomo 2018 MiPschool Tromso C4
Luis Crisostomo
Mitochondrion at the crosstalk between metabolic disease and dysfunction in male fertility?
Dahdah 2018 MiPschool Tromso
MiPsociety
No abstract.
Detraux 2018 MiPschool Tromso
Detraux Damian
No abstract.
Dubouchaud 2018 MiPschool Tromso
Dubouchaud Herve
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Ferreira 2018 MiPschool Tromso
Ferreira Luciana
No abstract.
Fischer 2018 MiPschool Tromso E2
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
Garipi 2018 MiPschool Tromso E2Phenotyping mitochondrial metabolism in Barrett’s metaplasia-dysplasia-adenocarcinoma sequence: respiratory capacity, extracelular proton flux and ROS production
Gnaiger 2018 MiPschool Tromso A1
Erich Gnaiger
Mitochondrial states and rates: 1. Electron transfer pathways and respiratory control. 2. Coupling control.
Gnaiger 2018 MiPschool Tromso A2
Erich Gnaiger
The protonmotive force and respiratory control. 1. Coupling of electron transfer reactions to vectorial translocation of protons. 2. From Einstein’s diffusion equation on gradients to Fick’s law on compartments.
Goncalo Teixeira 2018 MiPschool Tromso C1
MiPsociety
Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.
Handl 2018 MiPschool Tromso
MiPsociety
No abstract.
Harper 2018 MiPschool Tromso D1
Mary-Ellen Harper
OXPHOS efficiency in skeletal and cardiac muscles: Proton leaks, ROS and glutathione redox.
Harper 2018 MiPschool Tromso E1
Mary-Ellen Harper
Deacetylation acceleration of BAT thermogenesis.
Heiestad 2018 MiPschool Tromso
Christina Heiestad
No abstract.
Hoppel 2018 MiPschool Tromso D1
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
Hoppel 2018 MiPschool Tromso D2
Charles Hoppel
Mitochondrial function during ischemia/reperfusion injury.
Huete-Ortega 2018 MiPschool Tromso E2High-resolution respirometry: new perspectives for the study of bioenergetics in algae and plants.
Hyrossova 2018 MiPschool Tromso
MiPsociety
No abstract.
Iglesias-Gonzalez 2018 MiPschool Tromso E1 Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.
Isola 2018 MiPschool Tromso C3
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
Jansen 2018 MiPschool Tromso C2
MiPsociety
Dietary and pharmacological treatment of diet-induced obese mice – impact on mitochondrial function.
Jaskiewicz 2018 MiPschool Tromso
MiPsociety
No abstract.
Kampa 2018 MiPschool Tromso C2
Rafal Kampa
Cardioprotective flavoniods as a natural modulators of mitoBKCa channel.
Kidere 2018 MiPschool Tromso E2
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
Krajcova 2018 MiPschool Tromso E2
Adela Krajcova
High-resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.
Larsen 2018 MiPschool Tromso
Larsen Terje
Local organizer
Li Puma 2018 MiPschool Tromso E2
MiPsociety
Fads2 exacerbates myocardial ischemia-reperfusion injury in mice: role of mitochondria.
Ma 2018 MiPschool Tromso C1
MiPsociety
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis.
Majtnerova 2018 MiPschool Tromso
MiPsociety
No abstract.
Makrecka-Kuka 2018 MiPschool Tromso E1
Marina Makrecka-Kuka
Cardiac fatty acid oxidation: from in vitro to in vivo.
Marstein 2018 MiPschool Tromso
MiPsociety
No abstract.
MartinsAD 2018 MiPschool Tromso E2
MiPsociety
Mitochondrial dynamics of human Sertoli cells under the effect of leptin and ghrelin.
MartinsJD 2018 MiPschool Tromso C2
MiPsociety
Sweetheart: Cardiac consequences of fetal exposure to maternal gestational diabetes on the offspring mitochondrial function.
Murray 2018 MiPschool Tromso E1
Andrew Murray
OXPHOS protocols: understanding the patterns.
Musiol 2018 MiPschool Tromso C4
MiPsociety
Alpha-tomatine as a novel membrane-permeabilizing agent for mitochondrial respiration measurements.
Pedersen 2018 MiPschool Tromso
MiPsociety
No abstract.
Pereira 2018 MiPschool Tromso C1
Pereira Susana P
Obesity-induced mitochondrial hepatic changes during pregnancy.
Puurand 2018 MiPschool Tromso E2
MiPsociety
Intracellular energy-transfer networks in health and disease – the results of oxygraphic studies.
Schartner 2018 MiPschool Tromso
Schartner Melanie
Schlattner 2018 MiPschool Tromso B1
Uwe Schlattner
Mitochondrial kinases: key players in respiratory control and energy transfer.
Schots 2018 MiPschool Tromso
MiPsociety
Siewiera 2018 MiPschool Tromso E2
Karolina Siewiera
Effect of metformin treatment on blood platelet bioenergetics and platelet function in STZ-diabetic and non-diabetic rats.
Storder 2018 MiPschool Tromso E2
Storder J
Investigaton on the role of the mitochondiral deacetylase Sirtuin 3 in adipose tissue.
Template 2018 MiPschool Tromso
MiPsociety
Torp 2018 MiPschool Tromso C3
MiPsociety
Intracellular complement factor 3 in the heart – a link to metabolism?
Truu 2018 MiPschool Tromso
Truu Laura
No abstract.
Tuncay 2018 MiPschool Tromso C2
MiPsociety
MitoTEMPO ameliorates hyperglycemia induced mitochondrial damage in cardiomyocytes.
Vella 2018 MiPschool Tromso C4
Joanna Vella
Exome analysis sheds light on mitochondrial disorders.
Vendelin 2018 MiPschool Tromso B1
Marko Vendelin
Restrictions to intracellular diffusion of ATP and ADP in cardiomyocytes.
Vendelin 2018 MiPschool Tromso D2
Marko Vendelin
Modeling actomyosin contraction in the heart muscle.
Vendelin 2018 MiPschool Tromso E1
Marko Vendelin
Introducing a platform for primary kinetics data analysis.
Vieira Ligo Teixeira 2018 MiPschool Tromso
MiPsociety
No abstract.
Vujacic-Mirski 2018 MiPschool Tromso C4
MiPsociety
Development of analytical assays for the detection and quantification of reactive oxygen and nitrogen species in an animal model of type 1 diabetes - ROS formation involving mitochondrial and NADPH oxidase.
Wiesner 2018 MiPschool Tromso E1
MiPsociety
Aging-related accumulation of mitochondrial DNA deletions in skeletal muscle occurs preferentially in Type IIb fibers – high mitophagic flux protects Type I fibers.
Wuest 2018 MiPschool Tromso D3
Wuest Rob
Metabolic flexibility and mitochondrial function in the diabetic heart.
Zdrazilova 2018 MiPschool Tromso C4
MiPsociety
Bioenergetic characterization of skin fibroblasts from patients with congenital disorders of glycosylation.
Zobalova 2018 MiPschool Tromso
MiPsociety
No abstract.


Support

MitoEAGLE Scholarships

  1. Eligibility: Participants from all COST countries can apply - MitoEAGLE network.
  2. Late registration: The COST MitoEAGLE grant is a financial support to cover part of the local costs (accommodation, meals).
Âť Notification of MitoEAGLE scholarships for late registrations will be given until September 20.


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