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Difference between revisions of "Nitric oxide synthase"

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|description='''Nitric oxide synthase''', NOS, catalyzes the production of nitric oxide (NO•), which is a [[reactive nitrogen species]]. There are four types of NOS: neuronal NOS (nNOS), endothelial NOS (eNOS), inducible NOS (iNOS) and mitochondrial NOS (mtNOS).
|description='''Nitric oxide synthase''', NOS, catalyzes the production of nitric oxide (NO•), which is a [[reactive nitrogen species]]. There are four types of NOS: neuronal NOS (nNOS), endothelial NOS (eNOS), inducible NOS (iNOS) and mitochondrial NOS (mtNOS).
|info=[[Ghafourifar 1997 FEBS Lett]]
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The significance of mitochondrial nitric oxide synthase is debated. mtNOS presents two isoforms: a constitutive (c-mtNOS) and an inducible (i-mtNOS) isoform. In normal conditions, both isoforms contribute equally to the production of mitochondrial NO•. However, in an inflammatory process occurs an induction of mtNOS generating high amounts of NO•.
The significance of mitochondrial nitric oxide synthase is debated. mtNOS presents two isoforms: a constitutive (c-mtNOS) and an inducible (i-mtNOS) isoform. In normal conditions, both isoforms contribute equally to the production of mitochondrial NO•. However, in an inflammatory process occurs an induction of mtNOS generating high amounts of NO•.
Ghafourifar P (1997) Nitric oxide synthase activity in mitochondria.

Latest revision as of 17:05, 5 November 2014


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Nitric oxide synthase

Description

Nitric oxide synthase, NOS, catalyzes the production of nitric oxide (NO•), which is a reactive nitrogen species. There are four types of NOS: neuronal NOS (nNOS), endothelial NOS (eNOS), inducible NOS (iNOS) and mitochondrial NOS (mtNOS).

Abbreviation: NOS

Reference: Ghafourifar 1997 FEBS Lett



MitoPedia topics: Enzyme 

mtNOS

The significance of mitochondrial nitric oxide synthase is debated. mtNOS presents two isoforms: a constitutive (c-mtNOS) and an inducible (i-mtNOS) isoform. In normal conditions, both isoforms contribute equally to the production of mitochondrial NO•. However, in an inflammatory process occurs an induction of mtNOS generating high amounts of NO•.