Difference between revisions of "Oxidative phosphorylation"
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{{MitoPedia | {{MitoPedia | ||
|abbr=OXPHOS | |abbr=OXPHOS | ||
|description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of [[ADP]] to [[ATP]] and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state | |description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of [[ADP]] to [[ATP]] (PΒ») and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state of respiration provides a measure of [[OXPHOS capacity]] (''P''), which is frequently corrected for [[residual oxygen consumption]] (ROX). | ||
|info=[[OXPHOS capacity]] | |info=[[OXPHOS capacity]] | ||
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Β Contributed by [[Gnaiger E]] 2010-09-10, edited 2014-11-02. | Β Contributed by [[Gnaiger E]] 2010-09-10, edited 2014-11-02. | ||
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive | [[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment ([[Gnaiger 2014 MitoPathways]]).]] | ||
== OXPHOS == | == OXPHOS == | ||
'''Figure''': Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H+out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive | '''Figure''': Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H+out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment (from [[Gnaiger 2014 MitoPathways |Gnaiger 2014]]). | ||
== Related terms in Bioblast == | == Related terms in Bioblast == | ||
:::: [[File:P.jpg |link=OXPHOS capacity]] [[OXPHOS capacity |OXPHOS]] | :::: [[File:P.jpg |link=OXPHOS capacity]] [[OXPHOS capacity |OXPHOS]]; ''P'' | ||
:::: [[File:R.jpg |link=ROUTINE respiration]] [[ROUTINE respiration |ROUTINE]] | :::: [[File:R.jpg |link=ROUTINE respiration]] [[ROUTINE respiration |ROUTINE]]; ''R'' | ||
:::: [[File:E.jpg |link= | :::: [[File:E.jpg |link=ET capacity]] [[ET capacity]]; ''E'' | ||
:::: [[File:L.jpg |link=LEAK respiration]] [[LEAK respiration |LEAK]] | :::: [[File:L.jpg |link=LEAK respiration]] [[LEAK respiration |LEAK]]; ''L'' | ||
:::: [[File:ROX.jpg]] [[Residual oxygen consumption |ROX]] | :::: [[File:ROX.jpg]] [[Residual oxygen consumption |ROX]]; ''Rox'' |
Revision as of 20:40, 4 January 2018
Description
Oxidative phosphorylation (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of ADP to ATP (PΒ») and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state of respiration provides a measure of OXPHOS capacity (P), which is frequently corrected for residual oxygen consumption (ROX).
Abbreviation: OXPHOS
Reference: OXPHOS capacity
MitoPedia concepts:
Respiratory state,
Recommended
MitoPedia methods:
Respirometry
MitoPedia topics:
EAGLE
Contributed by Gnaiger E 2010-09-10, edited 2014-11-02.
OXPHOS
Figure: Energy transformation in coupled fluxes, J, and forces, F and Ξp, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment (from Gnaiger 2014).
Related terms in Bioblast
- OXPHOS; P
- ROUTINE; R
- ET capacity; E
- LEAK; L
- ROX; Rox