Difference between revisions of "Oxidative phosphorylation"
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Β Contributed by [[Gnaiger E]] 2010-09-10, edited 2014-11-02. | Β Contributed by [[Gnaiger E]] 2010-09-10, edited 2014-11-02. | ||
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2019 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment ([[Gnaiger 2019 MitoPathways]]).]] | [[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2019 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment ([[Gnaiger 2019 MitoPathways]]).]] | ||
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|mitopedia concept=Respiratory state, Recommended | |||
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Revision as of 13:23, 17 May 2020
- high-resolution terminology - matching measurements at high-resolution
Oxidative phosphorylation
Description
Oxidative phosphorylation (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of ADP to ATP (PΒ») and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state of respiration provides a measure of OXPHOS-capacity (P), which is frequently corrected for residual oxygen consumption (ROX).
Abbreviation: OXPHOS
Reference: OXPHOS capacity
Contributed by Gnaiger E 2010-09-10, edited 2014-11-02.
OXPHOS
Figure: Energy transformation in coupled fluxes, J, and forces, F and Ξp, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive to the negative compartment (from Gnaiger 2014).
Related terms in Bioblast
- OXPHOS; P
ROUTINE; R
ET-capacity; E
LEAK; L
ROX; Rox
SUITbrowser question: OXPHOS respiration
- Β» OXPHOS-capacity
- OXPHOS respiration is the focus of several SUIT protocols. The SUITbrowser can be used to find SUIT protocols for this and other research questions.
References
| Bioblast link | Reference | Year |
|---|---|---|
| Gnaiger 2009 Int J Biochem Cell Biol | Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. https://doi.org/10.1016/j.biocel.2009.03.013 | 2009 |
| BEC 2020.1 doi10.26124bec2020-0001.v1 | Gnaiger E et al β MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 | 2020 |
MitoPedia concepts:
Respiratory state,
Recommended
MitoPedia methods:
Respirometry
MitoPedia topics:
EAGLE
