Difference between revisions of "Palmitoylcarnitine"
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'''Carnitine palmitoyltransferase I''' (CPT1) also known as '''carnitine acyltransferase I''' or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine. | '''Carnitine palmitoyltransferase I''' (CPT1) also known as '''carnitine acyltransferase I''' or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine. | ||
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::3) Divide into 0.2 mL portions. | ::3) Divide into 0.2 mL portions. | ||
::4) Store frozen at -20 °C. | ::4) Store frozen at -20 °C. | ||
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|mitopedia topic=Substrate and metabolite | |||
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Revision as of 14:02, 17 September 2020
- high-resolution terminology - matching measurements at high-resolution
Palmitoylcarnitine
Description
Palmitoylcarnitine is an ester derivative of carnitine (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the cell, palmitoylcarnitine is transported into the mitochondria to deliver palmitate for fatty acid oxidation and energy production.
Abbreviation: Pal
Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine.
Application in HRR
Pal: Palmitoylcarnitine (Palmitoyl-DL-carnitine-HCl, C23H45N04HCl); Sigma P 4509, 100 mg, store at -20 °C; FW = 436.1.
Preparation of 10 mM stock solution (dissolved in H2O):
- 1) Weigh 8.72 mg of palmitoylcarnitine.
- 2) Dissolve in 2 mL H2O.
- 3) Divide into 0.2 mL portions.
- 4) Store frozen at -20 °C.
MitoPedia topics:
Substrate and metabolite
