Difference between revisions of "Palmitoylcarnitine"
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|description='''Palmitoyl carnitine''' is an ester derivative of [[carnitine]] (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the cell, palmitoylcarnitine is transported into the mitochondria to deliver palmitate for fatty acid oxidation and energy production. | |description='''Palmitoyl carnitine''' is an ester derivative of [[carnitine]] (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the cell, palmitoylcarnitine is transported into the mitochondria to deliver palmitate for fatty acid oxidation and energy production. | ||
|type=Substrate ETS | |type=Substrate ETS | ||
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{{MitoPedia methods|type=Substrate ETS | |||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
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|type=Substrate ETS | |type=Substrate ETS | ||
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'''Carnitine palmitoyltransferase I''' (CPT1) also known as '''carnitine acyltransferase I''' or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine. | '''Carnitine palmitoyltransferase I''' (CPT1) also known as '''carnitine acyltransferase I''' or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine. | ||
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== Application in [[HRR]] == | == Application in [[HRR]] == | ||
'''Pal: Palmitoyl carnitine''' (Palmitoyl-DL-carnitine-HCl, C<sub>23</sub>H<sub>45</sub>N0<sub>4</sub>HCl); Sigma P 4509, 100 mg, store at -20 °C; FW = 436.1 | '''Pal: Palmitoyl carnitine''' (Palmitoyl-DL-carnitine-HCl, C<sub>23</sub>H<sub>45</sub>N0<sub>4</sub>HCl); Sigma P 4509, 100 mg, store at -20 °C; FW = 436.1. | ||
'''Preparation of 10 mM stock solution''' (dissolved in H<sub>2</sub>O): | '''Preparation of 10 mM stock solution''' (dissolved in H<sub>2</sub>O): | ||
::1) | ::1) Weigh 8.72 mg of palmitoyl carnitine. | ||
::2) | ::2) Dissolve in 2 ml H<sub>2</sub>O. | ||
::3) | ::3) Divide into 0.2 ml portions. | ||
::4) | ::4) Store frozen at -20 °C. | ||
Revision as of 19:17, 1 March 2014
- high-resolution terminology - matching measurements at high-resolution
Palmitoylcarnitine
Description
Palmitoyl carnitine is an ester derivative of carnitine (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the cell, palmitoylcarnitine is transported into the mitochondria to deliver palmitate for fatty acid oxidation and energy production.
Abbreviation: Pal
MitoPedia topics: Substrate and metabolite
Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine.
Application in HRR
Pal: Palmitoyl carnitine (Palmitoyl-DL-carnitine-HCl, C23H45N04HCl); Sigma P 4509, 100 mg, store at -20 °C; FW = 436.1.
Preparation of 10 mM stock solution (dissolved in H2O):
- 1) Weigh 8.72 mg of palmitoyl carnitine.
- 2) Dissolve in 2 ml H2O.
- 3) Divide into 0.2 ml portions.
- 4) Store frozen at -20 °C.
