Palmitoylcarnitine

high-resolution terminology - matching measurements at high-resolution

Palmitoylcarnitine

Description

Palmitoyl carnitine is an ester derivative of carnitine (long-chain acylcarnitine) involved in the metabolism of fatty acids. Within the cell, palmitoylcarnitine is transported into the mitochondria to deliver palmitate for fatty acid oxidation and energy production.

Abbreviation: Pal

MitoPedia topics: Substrate and metabolite 

Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I or CAT1 is a mitochondrial enzyme. CPT1 is associated with the outer mitochondrial membrane and mediates the transport of long-chain fatty acids across the membrane by binding them to carnitine.

Application in HRR

Pal: Palmitoyl carnitine (Palmitoyl-DL-carnitine-HCl, C₂₃H₄₅N0₄HCl); Sigma P 4509, 100 mg, store at -20 °C; FW = 436.1.

Preparation of 10 mM stock solution (dissolved in H₂O):

1) Weigh 8.72 mg of palmitoyl carnitine.

2) Dissolve in 2 ml H₂O.

3) Divide into 0.2 ml portions.

4) Store frozen at -20 °C.