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Shirihai 2014 Abstract MiP2014

From Bioblast
Mitochondrial dynamics and quality control, a conflict of interest.

Link:

MiP2014, Book of Abstracts Open Access

Shirihai Orian, Liesa M, Mahdaviani K, Trudeau K (2014)

Event: MiP2014


Labels: MiParea: Respiration, mt-Structure;fission;fusion, Patients  Pathology: Aging; senescence"Aging; senescence" is not in the list (Aging;senescence, Alzheimer's, Autism, Cancer, Cardiovascular, COPD, Diabetes, Inherited, Infectious, Myopathy, ...) of allowed values for the "Diseases" property., Diabetes, Obesity 

Organism: Human  Tissue;cell: Fat 




MiP2014 

Affiliation

Boston Univ School Medicine, MA, USA. - [email protected]

References

  1. Gomes LC, Di BG, Scorrano L (2011) During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat Cell Biol 13: 589-98.
  2. Liesa M, Shirihai OS (2013) Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab 17: 491-506.
  3. Mouli PK, Twig G, Shirihai OS (2009) Frequency and selectivity of mitochondrial fusion are key to its quality maintenance function. Biophys J 96: 3509-18.
  4. Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS (2008) Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 27: 433-46.
  1. Twig G, Liu X, Liesa M, Wikstrom JD, Molina AJ, Las G, Yaniv G, Hajnoczky G, Shirihai OS (2010) Biophysical properties of mitochondrial fusion events in pancreatic beta-cells and cardiac cells unravel potential control mechanisms of its selectivity. Am J Physiol Cell Physiol 299: C477-87.
  1. Wikstrom JD, Katzman SM, Mohamed H, Twig G, Graf SA, Heart E, Molina AJ, Corkey BE, de Vargas LM, Danial NN, Collins S, Shirihai OS (2007) beta-Cell mitochondria exhibit membrane potential heterogeneity that can be altered by stimulatory or toxic fuel levels. Diabetes 56: 2569-78.