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Steinlechner-Maran 1996 Am J Physiol Cell Physiol - Revision history
2024-03-29T13:34:35Z
Revision history for this page on the wiki
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https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=219926&oldid=prev
Gnaiger Erich at 01:45, 24 August 2021
2021-08-24T01:45:46Z
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=219870&oldid=prev
Gnaiger Erich at 21:17, 23 August 2021
2021-08-23T21:17:14Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Cited by ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Cited by ==</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=213448&oldid=prev
Gnaiger Erich at 16:03, 16 January 2021
2021-01-16T16:03:15Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Cited by ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Cited by ==</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=213056&oldid=prev
Gnaiger Erich at 08:37, 16 January 2021
2021-01-16T08:37:26Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 08:37, 16 January 2021</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>{{Template:Cited <del style="font-weight: bold; text-decoration: none;">in </del>Gnaiger 2000 BEC MitoPathways}}</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Cited by ==</ins></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration, mt-Biogenesis;mt-density</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration, mt-Biogenesis;mt-density</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=212631&oldid=prev
Gnaiger Erich at 16:43, 3 January 2021
2021-01-03T16:43:29Z
<p></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=Am J Physiol Cell Physiol</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=Am J Physiol Cell Physiol</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=We studied the oxygen dependence of respiration in cultured human umbilical vein endothelial cells by use of high-resolution respirometry. The [[ROUTINE respiration |rate of oxygen consumption]] varied from 30 to 50 pmol O<sub>2</sub> .s<sup>-1</sup>.10<sup>-6</sup> cells over a sixfold range of cell densities. Respiration was stimulated up to 3.5-fold by uncoupling with [[FCCP |carbonyl cyanide ''p''-trifluoromethoxyphenylhydrazone]] or 2,4-[[Dinitrophenole]], and the ''p''<sub>O2</sub> at half-maximal respiration (''p''<sub>50</sub>) increased from 0.05 to 0.12 kPa (0.3 to 0.9 Torr) with respiratory rate. ''p''<sub>50</sub> decreased to a minimum of 0.02 kPa when uncoupled cells were inhibited to control levels. Differences in cell size explained a variation of approximately 0.015 kPa in ''p''<sub>50</sub> at similar respiratory rates per cell. Oxygen diffusion to mitochondria contributed maximally 30% to the regulation of ''p''<sub>50</sub> in coupled cells, as deduced from the shallow slope of the flux dependence of ''p''<sub>50</sub> in uncoupled-inhibited cells compared with the slope in coupled cells. Therefore 70% of the flux dependence of ''p''<sub>50</sub> in coupled cells was caused by changes in metabolic state, which correlated with respiratory rate.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=We studied the oxygen dependence of respiration in cultured human umbilical vein endothelial cells by use of high-resolution respirometry. The [[ROUTINE respiration |rate of oxygen consumption]] varied from 30 to 50 pmol O<sub>2</sub> .s<sup>-1</sup>.10<sup>-6</sup> cells over a sixfold range of cell densities. Respiration was stimulated up to 3.5-fold by uncoupling with [[FCCP |carbonyl cyanide ''p''-trifluoromethoxyphenylhydrazone]] or 2,4-[[Dinitrophenole]], and the ''p''<sub>O2</sub> at half-maximal respiration (''p''<sub>50</sub>) increased from 0.05 to 0.12 kPa (0.3 to 0.9 Torr) with respiratory rate. ''p''<sub>50</sub> decreased to a minimum of 0.02 kPa when uncoupled cells were inhibited to control levels. Differences in cell size explained a variation of approximately 0.015 kPa in ''p''<sub>50</sub> at similar respiratory rates per cell. Oxygen diffusion to mitochondria contributed maximally 30% to the regulation of ''p''<sub>50</sub> in coupled cells, as deduced from the shallow slope of the flux dependence of ''p''<sub>50</sub> in uncoupled-inhibited cells compared with the slope in coupled cells. Therefore 70% of the flux dependence of ''p''<sub>50</sub> in coupled cells was caused by changes in metabolic state, which correlated with respiratory rate.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">» Coupling control protocol: [[1R;2U-]]</del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|mipnetlab=AT Innsbruck Gnaiger E</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|mipnetlab=AT Innsbruck Gnaiger E</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|discipline=Mitochondrial Physiology</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|discipline=Mitochondrial Physiology</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">::::» Coupling control protocol: [[1R;2U-]]</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{Template:Cited in Gnaiger 2000 BEC MitoPathways}}</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Labeling</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration, mt-Biogenesis;mt-density</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|area=Respiration, mt-Biogenesis;mt-density</div></td></tr>
</table>
Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=212384&oldid=prev
Gnaiger Erich at 22:54, 1 January 2021
2021-01-01T22:54:59Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|additional=SUIT-003 Ce1;ce2U-, Uncoupling</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|additional=SUIT-003 Ce1;ce2U-, Uncoupling<ins style="font-weight: bold; text-decoration: none;">, BEC 2020.2</ins></div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=201224&oldid=prev
Gnaiger Erich at 10:21, 17 May 2020
2020-05-17T10:21:17Z
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|additional=SUIT-003 Ce1;ce2U-,</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|additional=SUIT-003 Ce1;ce2U-, <ins style="font-weight: bold; text-decoration: none;">Uncoupling</ins></div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=170376&oldid=prev
Iglesias-Gonzalez Javier at 11:32, 21 January 2019
2019-01-21T11:32:11Z
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</table>
Iglesias-Gonzalez Javier
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=170325&oldid=prev
Iglesias-Gonzalez Javier at 10:23, 21 January 2019
2019-01-21T10:23:59Z
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Iglesias-Gonzalez Javier
https://wiki.oroboros.at/index.php?title=Steinlechner-Maran_1996_Am_J_Physiol_Cell_Physiol&diff=170324&oldid=prev
Iglesias-Gonzalez Javier at 10:22, 21 January 2019
2019-01-21T10:22:57Z
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