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Latest revision as of 08:52, 27 May 2024

Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. - »More details

-» A future for Ukraine is the future of its science

2024 Week 22

May-27 Mo

Same experimental conditions, but different O₂ fluxes in the left and right chambers?

Check for instrumental and operational factors that could be causing O₂ flux differences between the O2k-chambers.
- »Different O2 fluxes in left and right chamber«
- communicated by »Timon-Gomez Alba« and »Baglivo Eleonora«

May-28 Tu

May-29 We

May-30 Th

"Harmonization of isolation protocols yielding intact and enzymatically active mitochondria are critical to assess mitochondrial respiratory function"

- »MiPNet20.06 Isolation mouse heart mitochondria«
- communicated by »Cardoso Luiza« and »Leo Elettra«

May-31 Fr

Next Week

2024 Week 23

Jun-03 Mo

Jun-04 Tu

Jun-05 We

Jun-06 Th

"Silencing of mt-tRF-Leu^TAA in islet cells limits the inner mitochondrial membrane potential and impairs mitochondrial oxidative phosphorylation."

Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R (2024) The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion. »Bioblast link«

from the O2k-Network »CH Lausanne Place N«

Jun-07 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 43
+Week 22
-*'''Oct- 23 Mo'''
+* '''May-27 Mo'''
 :{|
-| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
+| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]
-|''' ''“Thanks for this excellent guidance and support thus far.”'''''<br>
+|'''Same experimental conditions, but different O<sub>2</sub> fluxes in the left and right chambers?'''<br>
-[[Maarman Gerald J|Maarman Gerald J]], from the O2k-Network Lab »[[ZA Cape Town Maarman GJ]]«<br>
+Check for instrumental and operational factors that could be causing O<sub>2</sub> flux differences between the O2k-chambers.
-- »'''[[O2k-Feedback]]'''«<br>
+<br>
+- »'''[[Different O2 fluxes in left and right chamber]]'''«<br>
+- communicated by »[[Timon-Gomez Alba]]« and »[[Baglivo Eleonora]]«
 |}
 ----
-*'''Oct- 24 Tu'''
+* '''May-28 Tu'''
-:{|
-| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/e/eb/Garcia_Menendez_2023_MitoFit.pdf |MitoFit pdf]]
-|'''A theoretical communication from Garcia Menendez on electromagnetic coupling hypothesis.'''<br>
-* Garcia Menendez R (2023) Update and a new statement of the electromagnetic coupling hypothesis to explain the translocation of protons in mitochondria, bacteria and chloroplasts. MitoFit Preprints 2023.8. https://doi.org/10.26124/mitofit:2023-0008
-|}
 ----
-*'''Oct- 25 We'''
+* '''May-29 We'''
 ----
-*'''Oct- 26 Th'''
+* '''May-30 Th'''
 :{|
-| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
+| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|'''"In collegiate swimmers, (…) a maximal exercise bout (i.e., the bucket test) was associated with minimal changes in ''cellular-level'' ''I''O<sub>2</sub> [oxygen flow in isolated PBMCs]. In contrast, due to the robust mobilization of immune cells in response to the maximal exercise bout, the ''tissue-level'' IO''<sub>2-Tissue</sub>'' [blood] was significantly elevated."''' <br>
+|''' "Harmonization of isolation protocols yielding intact and enzymatically active mitochondria are critical to assess mitochondrial respiratory function"'''<br>
-* Stampley JE, Cho E, Wang H, Theall B, Johannsen NM, Spielmann G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. [[Stampley 2023 Physiol Rep|»Bioblast link«]]
+- »'''[[MiPNet20.06_IsolationMouseHeart-mt|MiPNet20.06 Isolation mouse heart mitochondria]]'''«<br>
-:from the O2k-Network »[[US LA Baton Rouge Irving BA]]«
+- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«
 |}
 ----
-*'''Oct- 27 Fr'''
+* '''May-31 Fr'''
 ----
 '''<big>Next Week</big>'''
+Week 23
-Week 44
+* '''Jun-03 Mo'''
-*'''Oct- 30 Mo'''
 ----
-*'''Oct- 31 Tu'''
+* '''Jun-04 Tu'''
-:{|
-| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
-|''' How to interpret cytochrome ''c'' efficiency '''<br>
-Stimulation of OXPHOS or ET capacity upon addition of cytochrome ''c''  provides evidence of cytochrome ''c'' loss, indicating damage of the mitochondrial outer membrane, which could be caused by sample preparation or pathological conditions. <br>
-- »'''[https://wiki.oroboros.at/index.php/Cytochrome_c_control_efficiency Cytochrome ''c'' control efficiency]'''« <br>
-- communicated by »[[Schmitt Sabine]]« and »[[Leo Elettra]]«
-|}
 ----
-*'''Nov- 01 We'''
+* '''Jun-05 We'''
 ----
-*'''Nov- 02 Th'''
+* '''Jun-06 Th'''
-----
+:{|
-*'''Nov- 03 Fr'''
-:{|
 | width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"Peripheral impairments at the skeletal muscle level, namely reduced mitochondrial function and the presence of markers of impaired mitochondrial biogenesis emerged as major determinants of exercise intolerance and fatigue [in patients with post-acute sequelae of SARS-CoV-2 infection]"''' <br>
+|'''"Silencing of mt-tRF-Leu<sup>TAA</sup> in islet cells limits the inner mitochondrial membrane potential and impairs mitochondrial oxidative phosphorylation."''' <br>
-* Colosio M, Brocca L, Gatti M, Neri M, Crea E, Cadile F, Canepari M, Pellegrino MA, Polla B, Porcelli S, Bottinelli R (2023) Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection. [[Colosio 2023 J Appl Physiol (1985)|»Bioblast link«]]
+* Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R (2024) The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion. [[Jacovetti 2024 Mol Metab|»Bioblast link«]]
+:from the O2k-Network »[[CH Lausanne Place N]]«
 |}
+----
+* '''Jun-07 Fr'''
 ----