NS e-input: Difference between revisions
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|topics=Flux Control | |||
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|enzymes=Complex I, Complex II; Succinate Dehydrogenase | |enzymes=Complex I, Complex II; Succinate Dehydrogenase | ||
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Revision as of 14:19, 14 June 2014
- high-resolution terminology - matching measurements at high-resolution
NS e-input
Description
[[Description::CI+II e-input is electron input though Complexes CI plus CII simultaneously into the Q-junction corresponding to TCA cycle function in vivo, with convergent electron flow through the ETS. In mt-preparations, CI+II e-input requires addition not only of CI substrate (pyruvate+malate or glutamate+malate), but of succinate simultaneously, since metabolite depletion in the absence of succinate prevents a significant stimulation of CII.]]
Reference: [[Info::Gnaiger 2012 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol]]
MitoPedia methods:
Respirometry
Labels:
Enzyme: Complex I, Complex II; Succinate Dehydrogenase Regulation: Flux Control
