Difference between revisions of "Lopez-Lluch 2010 Mech Ageing Dev"
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{{Publication | {{Publication | ||
|title=Lopez-Lluch G, Rodriguez-Aguilera JC, Santos-Ocana C, Navas P (2010) Is coenzyme Q a key factor in aging? | |title=Lopez-Lluch G, Rodriguez-Aguilera JC, Santos-Ocana C, Navas P (2010) Is coenzyme Q a key factor in aging? Mech Ageing Dev 131:225-35. | ||
|info=[https://pubmed.ncbi.nlm.nih.gov/20193705/ PMID:20193705] | |info=[https://pubmed.ncbi.nlm.nih.gov/20193705/ PMID:20193705] | ||
|authors=Lopez-Lluch | |authors=Lopez-Lluch G, Rodriguez-Aguilera JC, Santos-Ocana C, Navas P | ||
|year=2010 | |year=2010 | ||
|journal=Mech Ageing Dev | |journal=Mech Ageing Dev | ||
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|editor=Komlodi T | |editor=Komlodi T | ||
}} | }} | ||
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Latest revision as of 22:30, 16 February 2021
Lopez-Lluch G, Rodriguez-Aguilera JC, Santos-Ocana C, Navas P (2010) Is coenzyme Q a key factor in aging? Mech Ageing Dev 131:225-35. |
Lopez-Lluch G, Rodriguez-Aguilera JC, Santos-Ocana C, Navas P (2010) Mech Ageing Dev
Abstract: Coenzyme Q (Q) is a key component for bioenergetics and antioxidant protection in the cell. During the last years, research on diseases linked to Q-deficiency has highlighted the essential role of this lipid in cell physiology. Q levels are also affected during aging and neurodegenerative diseases. Therefore, therapies based on dietary supplementation with Q must be considered in cases of Q deficiency such as in aging. However, the low bioavailability of dietary Q for muscle and brain obligates to design new mechanisms to increase the uptake of this compound in these tissues. In the present review we show a complete picture of the different functions of Q in cell physiology and their relationship to age and age-related diseases. Furthermore, we describe the problems associated with dietary Q uptake and the mechanisms currently used to increase its uptake or even its biosynthesis in cells. Strategies to increase Q levels in tissues are indicated.
โข Bioblast editor: Komlodi T
Cited by
- Komlรณdi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioenerg Commun 2021.3. https://doi.org/10.26124/bec:2021-0003
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