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MiP2014

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MiP2014: Mitochondrial Physiology - a Point/Counterpoint Meeting

The Mitochondrial Physiology Society, Obergurgl, Tyrol, Austria. 2014-Sep-08 to 12

Programme structure

A. Mitochondrial respiratory control

  • A1. mtDNA, mt-phenotype and disease โ€“ is there biochemical and molecular-genetic evidence to explain observed associations?
  • A2. Fission and fusion, mitochondrial structure and function - is there a tight connection?
  • A3. Mitochondrial density and normalization of respiration โ€“ is there a general biochemical or molecular marker?
  • A4. Biochemical reserve capacity, respiratory control ratios and coupling efficiency โ€“ are conventional concepts inconsistent?

B. Experimental protocols in mitochondrial biochemistry

  • B1. Incubation media for mt-preparations and experimental temperature in functional studies of mammalian mitochondria โ€“ guided by concept or merely tradition?
  • B2. Intracellular oxygen pressure versus oxygen regimes in studies of ROS production and respiration - are mitochondria sources or sinks of ROS?
  • B3. Quantitative measurement of mt-membrane potential - potentiometric/fluorometric.
  • B4. Instrumental platforms in mitochondrial physiology โ€“ industrial presentations.

C. Towards quality assurance

  • C1. Do blood cells versus muscle biopsies provide valid models for diagnosis of mitochondrial pathologies?
  • C2. Integrity of mitochondrial preparations โ€“ is a consensus possible on quality control criteria?
  • C3. Availability and quality control of chemicals used in mitochondrial research โ€“ who controls?
  • C4. Standards for the diagnosis of mitochondrial pathologies โ€“ a challenge for collaboration with mitochondrial organizations?


International programme committee

Chair:

Members (confirmed):

Members (invited):