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MiP2014
MiP2014 - 10th MiPconference
Joint IUBMB/MiP Symposium on Mitochondrial Physiology - Methods, Concepts and Biomedical Perspectives
International Union of Biochemistry and Molecular Biology and Mitochondrial Physiology Society
- Obergurgl, Tyrol, Austria. 2014-Sep-08 to 12
- » MiP2014 Book of Abstracts Open Access
- » MiP2014 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ..*
- » MiP2014 Photos
- » MiP2014 Feedback
MiP2014: Abstracts - alphabetical order
| Presentation | Session | |
|---|---|---|
| Alberici 2014 Abstract MiP2014 | Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. | C3 Poster |
| Ali 2014 Abstract MiP2014 | Oxygen-consuming and ROS-producing activities in synaptosomes. | B4 Oral |
| Amoedo 2014 Abstract MiP2014 | The metabolic panorama during tumor progression towards malignancy. | B3 Oral |
| Balazova 2014 Abstract MiP2014 | Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae. | A1 Poster |
| Borutaite 2014 Abstract MiP2014 | Controversies regarding cytochrome c test for mitochondrial membrane integrity. | C2 Oral |
| Bresciani Martins de Andrade 2014 Abstract MiP2014 | Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. | A4 Oral |
| Bristot 2014 Abstract MiP2014 | High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations. | C1 Oral |
| Brown DA 2014 Abstract MiP2014 | The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes. | C3 Oral |
| Brown G 2014 Abstract MiP2014 | Complex I inhibition in microglia and inflammatory neuronal loss. | C1 Oral |
| Burtscher 2014 Abstract MiP2014 | Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain. | A4 Oral |
| Busch 2014 Abstract MiP2014 | Mitochondrial fusion and fission dynamics are indispensable for homogenization of inner mitochondrial membrane proteins: insights from superresolution studies. | |
| Cherubini 2014 Abstract MiP2014 | Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease. | A2 P-flash |
| Coen 2014 Abstract MiP2014 | Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery. | A3 Oral |
| Contreras-Ferrat 2014 Abstract MiP2014 | Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13. | C3 Oral |
| Dohlmann 2014 Abstract MiP2014 | Mitochondrial adaptations to high-intensity training in young and elderly men and women. | A3 Oral |
| Eggimann 2014 Abstract MiP2014 | Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins. | C1 Oral |
| Eide 2014 Abstract MiP2014 | Reversible mitochondrial DNA mutagenesis. | A1 Oral |
| El-Bacha 2014 Abstract MiP2014 | Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells. | C3 Oral |
| Felser 2014 Abstract MiP2014 | Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry. | B4 Oral |
| Ferreira 2014 Abstract MiP2014 | Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats. | C3 Poster |
| Figueira 2014 Abstract MiP2014 | Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity. | C2 Oral |
| Galina 2014 Abstract MiP2014 | Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system. | B3 Oral |
| Gnaiger 2014 Abstract MiP2014 | Cell ergometry: OXPHOS and ET-pathway coupling efficiency. | A4 Oral |
| Gnaiger 2014 Preface MiP2014 | MiPArt - Mitchell's equation. | |
| Grefte 2014 Abstract MiP2014 | Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II. | B3 P-flash |
| Hahn 2014 Abstract MiP2014 | Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases. | C1 Poster |
| Harrison 2014 Abstract MiP2014 | The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. | B4 Oral |
| Hepple 2014 Abstract MiP2014 | Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention. | A3 Oral |
| Herbst 2014 Abstract MiP2014 | Analysis of mitochondrial function in multiple brain regions through in situ permeabilization. | A4 Oral |
| Herminghaus 2014 Abstract MiP2014 | Severity of polymicrobial sepsis modulates mitochondrial function in rat liver. | A4 Poster |
| Hickey 2014 Abstract MiP2014 | Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. | B4 Oral |
| Holloway 2014 Abstract MiP2014 | Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions. | B2 Oral |
| Holmstroem 2014 Abstract MiP2014 | Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome. | A1 Oral |
| Horscroft 2014 Abstract MiP2014 | Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch? | B3 Oral |
| Houghton 2014 Abstract MiP2014 | The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes. | B2 Oral |
| Houstek 2014 Abstract MiP2014 | Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. | A1 Poster |
| Iyer 2014 Abstract MiP2014 | Bioenergetics: arts meets gentle science in sickness and in health. | C4 Oral |
| Jaburek 2014 Abstract MiP2014 | The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. | B2 Oral |
| Jana Prado 2014 Abstract MiP2014 | Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13. | C3 P-flash |
| Jezek 2014 Abstract MiP2014 | Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia. | A2 Oral |
| Kabir 2014 Abstract MiP2014 | Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay. | C3 Oral |
| Kandashvili 2014 Abstract MiP2014 | Regulation of energy metabolism in human colorectal cancer cells in situ. | B3 Poster |
| Kane 2014 Abstract MiP2014 | Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect. | C2 Oral |
| Kluckova 2014 Abstract MiP2014 | Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13. | C4 Oral |
| Komlodi 2014 Abstract MiP2014 | Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation. | B1 Poster |
| Koopman 2014 Abstract MiP2014 | Redox regulation of mitochondrial dynamics and function. | A2 Oral |
| Kowaltowski 2014 Abstract MiP2014 | Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation. | A1 Oral |
| Krumschnabel 2014 Abstract MiP2014 | Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. | B4 Poster |
| Kruszewski 2014 Abstract MiP2014 | Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species. | A1 P-flash |
| Lai 2014 Abstract1 MiP2014 | Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle. | C2 Oral |
| Lai 2014 Abstract2 MiP2014 | Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes. | C2 Poster |
| Laner 2014 Abstract MiP2014 | Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibers. | C2 Poster |
| Larsen 2014 Abstract MiP2014 | The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. | A3 Oral |
| MacDonald 2014 Abstract MiP2014 | The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle. | B1 Oral |
| Maddalena 2014 Abstract MiP2014 | Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA. | C3 Poster |
| Mahdaviani 2014 Abstract MiP2014 | Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. | A2 Oral |
| Meszaros 2014 Abstract MiP2014 | Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs. | C2 Oral |
| Mracek 2014 Abstract MiP2014 | Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13. | C4 P-flash |
| Nagy 2014 Abstract MiP2014 | Investigation of the energy metabolism of microglial cells. | C1 Poster |
| Neufer 2014 Abstract MiP2014 | Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. | A4 Oral |
| Oparka 2014 Abstract MiP2014 | Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells. | B2 Oral |
| Paju 2014 Abstract MiP2014 | Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts. | C1 Oral |
| Pecina 2014 Abstract MiP2014 | Manifestation of mitochondrial disorders of nuclear origin in lymphocytes. | C1 Oral |
| Perry 2014 Abstract MiP2014 | Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibers. | B1 Oral |
| Pesta 2014 Abstract MiP 2014 | Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c. | A1 Oral |
| Picard 2014 Abstract MiP2014 | Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy. | A1 Oral |
| Power 2014 Abstract MiP2014 | The hot heart: cardiac mitochondrial energetics during hyperthermia. | C4 Oral |
| Purhonen 2014 Abstract MiP2014 | Effect of ketogenic diet in mouse model of the mitochondrial hepatopathy GRACILE syndrome. | |
| Rodrigues 2014 Abstract MiP2014 | Bioenergetics’ traits of tongue cancer metastatic cells. | B3 Poster |
| Roy 2014 Abstract MiP2014 | Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells. | C3 Oral |
| Schoepf 2014 Abstract MiP2014 | OXPHOS analysis in small prostate biopsies. | A4 Oral |
| Shirihai 2014 Abstract MiP2014 | Mitochondrial dynamics and quality control, a conflict of interest. | A2 Oral |
| Skulachev 2014 Abstract MiP2014 | Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants. | B2 Oral |
| Sokolova 2014 Abstract MiP2014 | Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves. | B3 Oral |
| Sparks 2014 Abstract MiP2014 | NAMPT remodels substrate metabolism in skeletal muscle. | B1 Oral |
| Spendiff 2014 Abstract MiP2014 | Lessons from the master athlete: mitochondrial contributions to aging. | A3 Oral |
| Starkov 2014 Abstract MiP2014 | Mitochondria as H2O2 buffering system. | B2 Oral |
| Stiban 2014 Abstract MiP2014 | Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis. | C4 Oral |
| Sumbalova 2014 Abstract MiP2014 | Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain. | B1 Oral |
| Timon-Gomez 2014 Abstract MiP2014 | The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. | B3 P-flash |
| Tretter 2014 Abstract MiP2014 | Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia. | C4 Oral |
| Trudeau 2014 Abstract MiP2014 | Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network. | A2 P-flash |
| Volodina 2014 Abstract MiP2014 | Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy. | B1 Oral |
| Widlund 2014 Abstract MiP2014 | Resveratrol as a double edged sword on mitochondrial function. | B4 Oral |
| Wieckowski 2014 Abstract MiP2014 | Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases. | C4 P-flash |
| Wohlwend 2014 Abstract MiP2014 | Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people. | A3 Oral |
| Wojtala 2014 Abstract MiP2014 | Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues. | A1 P-flash |
| Zapisek 2014 Abstract MiP2014 | YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae. | A1 Poster |
| Zorzano 2014 Abstract MiP2014 | Metabolic implications of mitofusin 2 dysfunction. | A2 Oral |
MiP2014 Programme: Abstracts in sequential sessions
» MiP2014 Programme and list of Participants.pdf
- Oral = 10 + 5 min: All talks are 10 min plus 5 min discussion. The invited lecturers provide generously an opportunity to a majority of MiPparticipants to present their work orally, from senior scientists to students.
- P-flash = 5 + 2 min: Flash presentations or poster flashes are 5 min plus 2 min discussion. You may optionally present your work in addition as a poster (please confirm until August 24, if you choose to bring a poster; poster space will be limited).
- Poster = Poster presentation: Posters are up during the entire conference, providing an excellent opportunity for person-to-person discussions and for integrating your work into discussions in the plenary sessions.
A: Mitochondrial respiratory control
A1: From genotype to mitochondrial phenotypes in health and disease
- Tuesday, Sep 09, 08:30-10:00 »Help - Further information - Make full use of the MiPMap
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Pesta 2014 Abstract MiP 2014 | A1 Oral | Dysregulation of muscle ATP synthesis in hypophosphatemic mouse models and in a patient with hypophosphatemia due to a mutation in NaPi2c. | Exercise physiology;nutrition;life style Patients | Human Mouse | Skeletal muscle | Diabetes | |
| Picard 2014 Abstract MiP2014 | A1 Oral | Quantitative regulation of nuclear gene expression by mitochondrial DNA heteroplasmy. | mtDNA;mt-genetics mt-Medicine Patients | Other cell lines | |||
| Wojtala 2014 Abstract MiP2014 | A1 P-flash | Proteomic analysis of mitochondrial Complex I deficient mouse model - impact of Complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mouse tissues. | Mouse | Oxidative stress;RONS | |||
| Zapisek 2014 Abstract MiP2014 | A1 Poster | YER077C encodes a novel PPR protein essential for mitochondrial genome expression in Saccharomyces cerevisiae. | mtDNA;mt-genetics | Saccharomyces cerevisiae | |||
| Balazova 2014 Abstract MiP2014 | A1 Poster | Balanced ratio of anionic mitochondrial phospholipids is important for mitochondrial functions in the yeast Saccharomyces cerevisiae. | Respiration | Saccharomyces cerevisiae | Temperature | ||
| Eide 2014 Abstract MiP2014 | A1 Oral | Reversible mitochondrial DNA mutagenesis. | mtDNA;mt-genetics | Human | Nervous system Stem cells | Aging;senescence | |
| Holmstroem 2014 Abstract MiP2014 | A1 Oral | Homozygous missense mutation in the human NARS2 gene results in reduced homodimerization of mitochondrial AsnRS enzyme in a patient with Alpers syndrome. | mtDNA;mt-genetics mt-Medicine Patients | Human | Fibroblast | Neurodegenerative | |
| Houstek 2014 Abstract MiP2014 | A1 Poster | Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. | mtDNA;mt-genetics mt-Medicine Patients | ||||
| Kowaltowski 2014 Abstract MiP2014 | A1 Oral | Luévano-Martínez LA, Forni FM, dos Santos VT, Souza-Pinto NC, Kowaltowski AJ (2014) Cardiolipin is a key determinant for mitochondrial DNA stability and segregation. | Respiration mt-Membrane mtDNA;mt-genetics | Saccharomyces cerevisiae | Temperature | ||
| Kruszewski 2014 Abstract MiP2014 | A1 P-flash | Complementation of nuclear-encoded proteins which maintain mitochondrial DNA in S. cerevisiae with homologous proteins from other fungi species. | mtDNA;mt-genetics | Saccharomyces cerevisiae Fungi |
A2: Mitochondrial structure and function: fission and fusion to supercomplexes
- Tuesday, Sep 09, 10:30-12:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Cherubini 2014 Abstract MiP2014 | A2 P-flash | Striatal deregulation of Cdk5 alters mitochondrial dynamics in Huntington’s disease. | mt-Structure;fission;fusion | Nervous system | Mitochondrial disease | Neurodegenerative | |
| Mahdaviani 2014 Abstract MiP2014 | A2 Oral | Hormone‐induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. | Respiration mt-Structure;fission;fusion mt-Membrane | Mouse | Fat Other cell lines | ||
| Shirihai 2014 Abstract MiP2014 | A2 Oral | Mitochondrial dynamics and quality control, a conflict of interest. | Respiration mt-Structure;fission;fusion Patients | Human | Fat | Aging;senescence Diabetes Obesity | |
| Trudeau 2014 Abstract MiP2014 | A2 P-flash | Role of mitochondrial fusion and motility in distributing young mitochondrial protein and removing old protein from the mitochondrial network. | mt-Structure;fission;fusion | ||||
| Zorzano 2014 Abstract MiP2014 | A2 Oral | Metabolic implications of mitofusin 2 dysfunction. | Respiration mt-Structure;fission;fusion Exercise physiology;nutrition;life style | Mouse | Skeletal muscle | Diabetes Obesity | |
| Jezek 2014 Abstract MiP2014 | A2 Oral | Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia. | Respiration mt-Structure;fission;fusion mt-Membrane | Other cell lines | Ischemia-reperfusion | ||
| Koopman 2014 Abstract MiP2014 | A2 Oral | Redox regulation of mitochondrial dynamics and function. | mt-Structure;fission;fusion mtDNA;mt-genetics | Oxidative stress;RONS |
A3: Mitochondrial response to exercise and aging
- Tuesday, Sep 09, 15:30-17:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Coen 2014 Abstract MiP2014 | A3 Oral | Exercise improves insulin sensitivity and muscle mitochondrial respiration following Roux-en-Y gastric bypass surgery. | Respiration Exercise physiology;nutrition;life style mt-Medicine Patients | Human | Skeletal muscle | Diabetes | |
| Spendiff 2014 Abstract MiP2014 | A3 Oral | Lessons from the master athlete: mitochondrial contributions to aging. | Respiration mtDNA;mt-genetics Exercise physiology;nutrition;life style | Human | Skeletal muscle | Oxidative stress;RONS | Aging;senescence |
| Wohlwend 2014 Abstract MiP2014 | A3 Oral | Exercise modality specific mitochondrial adaptations in skeletal muscle of elderly people. | Respiration mt-Biogenesis;mt-density Exercise physiology;nutrition;life style | Human | Skeletal muscle | Aging;senescence | |
| Dohlmann 2014 Abstract MiP2014 | A3 Oral | Mitochondrial adaptations to high-intensity training in young and elderly men and women. | Respiration Exercise physiology;nutrition;life style | Human | Skeletal muscle HeLa Fibroblast | Aging;senescence | |
| Hepple 2014 Abstract MiP2014 | A3 Oral | Denervation modulates mitochondrial function when aging muscle atrophy becomes severe: implications for therapeutic intervention. | Respiration Exercise physiology;nutrition;life style mt-Medicine | Human | Skeletal muscle | Cell death Permeability transition Oxidative stress;RONS Mitochondrial disease | Aging;senescence |
| Larsen 2014 Abstract MiP2014 | A3 Oral | The effect of high intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. | Respiration mt-Biogenesis;mt-density Exercise physiology;nutrition;life style | Human | Skeletal muscle Fat | Obesity |
A4: Coupling efficiency and mitochondrial respiratory control
- Tuesday, Sep 09, 17:30-19:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Bresciani Martins de Andrade 2014 Abstract MiP2014 | A4 Oral | Mitochondrial function in white adipose tissue: palmitoleic acid (C16:1n7) treatment enhances white adipocyte oxygen consumption. | Respiration | Fat | Diabetes Obesity | ||
| Burtscher 2014 Abstract MiP2014 | A4 Oral | Region-specific differences in Complex I- and Complex II-linked respiration in the mouse brain. | Respiration | Mouse | Nervous system | ||
| Neufer 2014 Abstract MiP2014 | A4 Oral | Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. | Respiration | Mouse | Skeletal muscle | ||
| Schoepf 2014 Abstract MiP2014 | A4 Oral | OXPHOS analysis in small prostate biopsies. | Respiration Patients | Human | Genital | Oxidative stress;RONS | Cancer |
| Gnaiger 2014 Abstract MiP2014 | A4 Oral | Cell ergometry: OXPHOS and ET-pathway coupling efficiency. | Respiration | ||||
| Herbst 2014 Abstract MiP2014 | A4 Oral | Analysis of mitochondrial function in multiple brain regions through in situ permeabilization. | Respiration | Mouse | Nervous system | ||
| Herminghaus 2014 Abstract MiP2014 | A4 Poster | Severity of polymicrobial sepsis modulates mitochondrial function in rat liver. | Respiration mt-Medicine | Rat | Liver | Sepsis |
B. Experimental protocols and mitochondrial biochemistry
B1: Experimental regimes in functional studies of mitochondrial preparations
- Wednesday, Sep 10, 08:30-10:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| MacDonald 2014 Abstract MiP2014 | B1 Oral | The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle. | Respiration | Rat | Heart Nervous system Liver Kidney | ||
| Perry 2014 Abstract MiP2014 | B1 Oral | Evaluation of critical experimental parameters for assessing mitochondrial bioenergetics in permeabilized myofibers. | Respiration Instruments;methods | Human | Skeletal muscle | ||
| Sparks 2014 Abstract MiP2014 | B1 Oral | NAMPT remodels substrate metabolism in skeletal muscle. | Respiration mt-Biogenesis;mt-density Exercise physiology;nutrition;life style | Mouse | Skeletal muscle | ||
| Sumbalova 2014 Abstract MiP2014 | B1 Oral | Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain. | Respiration Instruments;methods | Rat | Nervous system Liver | ||
| Volodina 2014 Abstract MiP2014 | B1 Oral | Multipotent stromal cells injection improves rat liver regeneration through activation of mitochondrial functions after subtotal hepatectomy. | Respiration | Rat | Liver | Oxidative stress;RONS | |
| Komlodi 2014 Abstract MiP2014 | B1 Poster | Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation. | Respiration | Guinea pig | Nervous system | Ischemia-reperfusion | Alzheimer's Parkinson's |
B2: Are mitochondria sources or sinks of reactive oxygen species?
- Wednesday, Sep 10, 10:30-12:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Holloway 2014 Abstract MiP2014 | B2 Oral | Acute diet-induced insulin resistance is associated with increased adipose tissue mitochondrial ROS emissions. | Respiration Exercise physiology;nutrition;life style | Mouse | Fat | Oxidative stress;RONS | Diabetes Obesity |
| Oparka 2014 Abstract MiP2014 | B2 Oral | Investigation of the mitochondrial functions to understand p66Shc and reactive oxygen species interplay in tumor cells. | Respiration | Human | Oxidative stress;RONS | Cancer | |
| Skulachev 2014 Abstract MiP2014 | B2 Oral | Mitochondria are sources, rather than sinks, of reactive oxygen species. Effects of mitochondria-targeted antioxidants. | mt-Membrane mt-Medicine Patients | Mouse Rat | Oxidative stress;RONS | Aging;senescence Inherited | |
| Starkov 2014 Abstract MiP2014 | B2 Oral | Mitochondria as H2O2 buffering system. | Oxidative stress;RONS | ||||
| Houghton 2014 Abstract MiP2014 | B2 Oral | The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes. | Respiration Exercise physiology;nutrition;life style | Human | Liver | Oxidative stress;RONS | Diabetes |
| Jaburek 2014 Abstract MiP2014 | B2 Oral | The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. | Respiration | Islet cell;pancreas;thymus | Oxidative stress;RONS | Diabetes |
B3: Hypoxia, respiration and fermentation - mitochondrial physiology in cellular energetics
- Wednesday, Sep 10, 15:30-17:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Amoedo 2014 Abstract MiP2014 | B3 Oral | The metabolic panorama during tumor progression towards malignancy. | Respiration | Other cell lines | Cancer | ||
| Rodrigues 2014 Abstract MiP2014 | B3 Poster | Bioenergetics’ traits of tongue cancer metastatic cells. | Respiration mt-Biogenesis;mt-density | Mouse | Lymphocyte | Cancer | |
| Sokolova 2014 Abstract MiP2014 | B3 Oral | Bioenergetic responses to cyclic hypoxia reveal mitochondrial mechanisms of hypoxia tolerance in marine bivalves. | Respiration Comparative MiP;environmental MiP | Other invertebrates | Ischemia-reperfusion Oxidative stress;RONS | ||
| Timon-Gomez 2014 Abstract MiP2014 | B3 P-flash | The function of mitochondrial pyruvate carriers in the adaptation of respiration capacity and stress tolerance in yeast. | Respiration Comparative MiP;environmental MiP | Saccharomyces cerevisiae | Oxidative stress;RONS | ||
| Grefte 2014 Abstract MiP2014 | B3 P-flash | Myotube formation does not require mitochondrial ATP production but is inhibited by rotenone via the Rho-associated, coiled-coil containing protein kinase II. | Respiration Genetic knockout;overexpression Developmental biology | Mouse | Skeletal muscle | Oxidative stress;RONS | |
| Galina 2014 Abstract MiP2014 | B3 Oral | Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system. | Respiration mt-Membrane Developmental biology | Rat | Nervous system | Ischemia-reperfusion Permeability transition | |
| Horscroft 2014 Abstract MiP2014 | B3 Oral | Substrate utilisation in the hypoxic heart: a glycolysis/glucose oxidation mismatch? | Respiration | Rat | Heart | Ischemia-reperfusion | |
| Kandashvili 2014 Abstract MiP2014 | B3 Poster | Regulation of energy metabolism in human colorectal cancer cells in situ. | Respiration mt-Membrane | Human | Endothelial;epithelial;mesothelial cell | Cancer |
B4: Instrumental platforms: developments and applications in mitochondrial physiology
- Wednesday, Sep 10, 17:30-19:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Ali 2014 Abstract MiP2014 | B4 Oral | Oxygen-consuming and ROS-producing activities in synaptosomes. | Respiration Instruments;methods | Nervous system | Oxidative stress;RONS | ||
| Widlund 2014 Abstract MiP2014 | B4 Oral | Resveratrol as a double edged sword on mitochondrial function. | Respiration Pharmacology;toxicology | HeLa | |||
| Felser 2014 Abstract MiP2014 | B4 Oral | Assessing mitochondrial dysfunction in fibroblast cells – a comparison between O2k and multiwell respirometry. | Respiration | Human | Endothelial;epithelial;mesothelial cell HeLa Fibroblast | ||
| Harrison 2014 Abstract MiP2014 | B4 Oral | The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia. | Respiration | Rat Bovines | Heart | ||
| Hickey 2014 Abstract MiP2014 | B4 Oral | Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. | Respiration mt-Membrane | Rat | Heart | Ischemia-reperfusion Oxidative stress;RONS | Cardiovascular Diabetes Myopathy |
| Krumschnabel 2014 Abstract MiP2014 | B4 Poster | Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. | Respiration | Mouse | Nervous system | Oxidative stress;RONS |
C: Functional diagnosis to intervention
C1: Blood cells and cultured cells as models for diagnosis of mitochondrial pathologies
- Thursday, Sep 11, 08:30-10:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Bristot 2014 Abstract MiP2014 | C1 Oral | High-resolution respirometry and bioenergetics evaluation in fibroblasts derived from patients with TP53 germline mutations. | Respiration nDNA;cell genetics mt-Medicine | Human | Fibroblast | Oxidative stress;RONS | Cancer |
| Brown G 2014 Abstract MiP2014 | C1 Oral | Complex I inhibition in microglia and inflammatory neuronal loss. | Nervous system | Oxidative stress;RONS | Aging;senescence Parkinson's | ||
| Nagy 2014 Abstract MiP2014 | C1 Poster | Investigation of the energy metabolism of microglial cells. | Respiration | Human | Nervous system | ||
| Paju 2014 Abstract MiP2014 | C1 Oral | Characterization of the effects of pro-inflammatory cytokines on energy metabolism in human myoblasts. | Respiration Patients | Human | Skeletal muscle | Aging;senescence | |
| Pecina 2014 Abstract MiP2014 | C1 Oral | Manifestation of mitochondrial disorders of nuclear origin in lymphocytes. | Respiration mt-Medicine Patients | Human | Blood cells Lymphocyte | ||
| Eggimann 2014 Abstract MiP2014 | C1 Oral | Adaptation to nutrient availability in human fibroblasts with mitochondrial dysfunction: the role of sirtuins. | Respiration mt-Medicine Patients | Human | Fibroblast | Mitochondrial disease | |
| Hahn 2014 Abstract MiP2014 | C1 Poster | Validation of oxygen consumption measurements in muscle and fibroblasts from patients with mitochondrial diseases. | Respiration mt-Medicine Patients | Human | Skeletal muscle Fibroblast | Mitochondrial disease |
C2: Integrity of mitochondrial preparations and experimental quality control
- Thursday, Sep 11, 10:30-12:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Borutaite 2014 Abstract MiP2014 | C2 Oral | Controversies regarding cytochrome c test for mitochondrial membrane integrity. | Respiration mt-Membrane | Rat | Heart Nervous system | Ischemia-reperfusion Permeability transition | |
| Meszaros 2014 Abstract MiP2014 | C2 Oral | Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs. | Respiration Instruments;methods | Rat Guinea pig | |||
| Figueira 2014 Abstract MiP2014 | C2 Oral | Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity. | Respiration Gender | Rat | Heart Skeletal muscle Nervous system Liver | Permeability transition | |
| Laner 2014 Abstract MiP2014 | C2 Poster | Cytochrome c flux control factor as a quality criterion in respiratory OXPHOS analysis in canine permeabilized fibers. | Respiration | Dog | Skeletal muscle | ||
| Kane 2014 Abstract MiP2014 | C2 Oral | Assessing mitochondrial lactate oxidation in permeabilized skeletal muscle fibers highlights important experimental considerations: malate concentration and the cytochrome c effect. | Respiration | Rat | Skeletal muscle | ||
| Lai 2014 Abstract1 MiP2014 | C2 Oral | Improved isolation of high quality subsarcolemmal and interfibrillar mitochondria from skeletal muscle. | Respiration | Rat Dog | Heart Skeletal muscle Fibroblast | ||
| Lai 2014 Abstract2 MiP2014 | C2 Poster | Bioenergetic differences between permeabilized red and white fibers of a non-obese model of type II diabetes. | Respiration mt-Biogenesis;mt-density Exercise physiology;nutrition;life style | Rat | Skeletal muscle | Diabetes Obesity |
C3: Physiological and pharmacological intervention with mitochondrial function
- Thursday, Sep 11, 13:30-15:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Alberici 2014 Abstract MiP2014 | C3 Poster | Effects of long-chain acyl-CoA synthetase 6 knockdown in primary skeletal muscle cells metabolism. | Respiration Genetic knockout;overexpression | Rat | Skeletal muscle | Oxidative stress;RONS | Diabetes Obesity |
| Brown DA 2014 Abstract MiP2014 | C3 Oral | The cardiolipin-targeting peptide Bendavia preserves post-ischemic mitochondrial energetics by sustaining respiratory supercomplexes. | Respiration mt-Membrane Pharmacology;toxicology | Rat | Heart | Ischemia-reperfusion | |
| Contreras-Ferrat 2014 Abstract MiP2014 | C3 Oral | Insulin increases mitochondrial calcium levels regulating both mitochondrial function and intracellular signaling in muscle; this effect is disrupted in fibers from short-term high fat diet fed mice. Mitochondr Physiol Network 19.13. | Exercise physiology;nutrition;life style | Mouse | Skeletal muscle | Diabetes | |
| Maddalena 2014 Abstract MiP2014 | C3 Poster | Experimental considerations for evaluating bioenergetic effects of a mitochondria-targeted compound, TPP-IOA. | Respiration Pharmacology;toxicology | Cell death | |||
| Roy 2014 Abstract MiP2014 | C3 Oral | Differential expression of mitochondrial transporter proteins leads to incomplete fatty acid oxidation and insulin resistance in palmitate-treated muscle cells. | nDNA;cell genetics Exercise physiology;nutrition;life style | Rat | Skeletal muscle | Diabetes | |
| El-Bacha 2014 Abstract MiP2014 | C3 Oral | Cytotoxicity of grape pomace extract (Vitis vinifera L.) from Brazilian wine industry in human hepatocarcinoma HepG2 cells. | Respiration Pharmacology;toxicology | Human | Liver | Cell death | Cancer |
| Ferreira 2014 Abstract MiP2014 | C3 Poster | Impairment of bioenergetic parameters induced by acute carnosine administration in skeletal muscle of young rats. | Rat | Skeletal muscle | Inherited | ||
| Jana Prado 2014 Abstract MiP2014 | C3 P-flash | Defining the role of mitochondrial electron transfer Complex I on the modulation of Ca2+ homeostasis: effects of metformin on cancer cell metabolism. Mitochondr Physiol Network 19.13. | Respiration mt-Membrane Pharmacology;toxicology | Cancer Diabetes | |||
| Kabir 2014 Abstract MiP2014 | C3 Oral | Declining follicular reserve triggers mitochondrial pathway of granulosa cell apoptosis and accelerates the rate of follicular decay. | mt-Membrane Developmental biology | Rat | Genital | Cell death |
C4: Diagnosis and prevention of mitochondrial dysfunction
- Thursday, Sep 11, 15:30-17:00 »Help
| Session | Presentation | MiP areas | Mammals;models | Tissues;cells | Stress conditions | Pathological states | |
|---|---|---|---|---|---|---|---|
| Mracek 2014 Abstract MiP2014 | C4 P-flash | Function of mitochondrial energy provision apparatus is compromised in patients with chronic heart failure. Mitochondr Physiol Network 19.13. | Respiration mt-Biogenesis;mt-density Patients | Human | Heart | Cardiovascular | |
| Power 2014 Abstract MiP2014 | C4 Oral | The hot heart: cardiac mitochondrial energetics during hyperthermia. | Respiration | Rat | Heart | Permeability transition Temperature | |
| Stiban 2014 Abstract MiP2014 | C4 Oral | Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis. | mt-Membrane | Cell death | |||
| Tretter 2014 Abstract MiP2014 | C4 Oral | Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia. | Respiration Patients | Guinea pig | Nervous system | Oxidative stress;RONS Temperature | |
| Wieckowski 2014 Abstract MiP2014 | C4 P-flash | Understanding the utility and limitations of autopsy samples for mitochondrial studies - evaluation of oxidative stress in the central nervous system of patients with diagnosed or highly probable mitochondrial diseases. | mt-Medicine | Mouse | Nervous system | Oxidative stress;RONS | |
| Iyer 2014 Abstract MiP2014 | C4 Oral | Bioenergetics: arts meets gentle science in sickness and in health. | Exercise physiology;nutrition;life style mt-Awareness | Human | Obesity | ||
| Kluckova 2014 Abstract MiP2014 | C4 Oral | Proximal ubiquinone binding site in mitochondrial respiratory Complex II is a target for vitamin E analog MitoVES, an experimental anti-cancer agent. Mitochondr Physiol Network 19.13. | Respiration mtDNA;mt-genetics | Other cell lines | Cell death Oxidative stress;RONS | Cancer |
» MitoPedia: Respiratory states
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MitoGlobal Event
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MiP (2014-09-08) MitoGlobal
Abstract: 10th MiPconference: Joint IUBMB/MiP Symposium on Mitochondrial Physiology - a Point/Counterpoint Meeting, Obergurgl, Austria; with post-conference workshop 95th Oroboros O2k-Workshop.
Labels:
ORO, 2014, MiP
Sponsors, support and cooperation
Cooperation
Organizational team
- The local organizers acknowledge the assistance by the Oroboros-Team: Georg Kandolf, Sandra Fleischmann, Verena Erhart, Karina Fritz
Listed under MitoGlobal Events.
- Post-conference O2k-Workshop: Organized on the same venue, for hands-on training in mitochondrial respiratory physiology, introducing the combined measurement of high-resolution respirometry and fluorometry (Oroboros Instruments), financially separate from the symposium.
