Difference between revisions of "NS e-input"
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Revision as of 14:25, 8 February 2016
- high-resolution terminology - matching measurements at high-resolution
NS e-input
Description
CI&II e-input is electron input though Complexes CI and CII simultaneously into the Q-junction corresponding to TCA cycle function in vivo, with convergent electron flow through the ETS. In mt-preparations, CI&II e-input requires addition not only of CI-linked substrate (pyruvate+malate or glutamate+malate), but of succinate simultaneously, since metabolite depletion in the absence of succinate prevents a significant stimulation of CII-linked respiration. For more details, see: Additive effect of convergent CI&II electron flow.
Abbreviation: CI&II
Reference: Gnaiger 2014 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia methods: Respirometry
MitoPedia topics: Substrate and metabolite
