Difference between revisions of "Proton pump"
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{{MitoPedia | {{MitoPedia | ||
|description=Mitochondrial proton pumps are large enzyme complexes (CI, CII, CIV, CV) spanning the inner mt-membrane, partially encoded by mtDNA. [[CI]], [[CII]] and [[Complex_IV|CIV]] are proton pumps that drive | |description=Mitochondrial '''proton pumps''' are large enzyme complexes (CI, CII, CIV, CV) spanning the inner mt-membrane, partially encoded by mtDNA. [[CI]], [[CII]] and [[Complex_IV|CIV]] are proton pumps that drive [[proton]]s against the electrochemical [[protonmotive force]], driven by electron transfer from reduced substrates to oxygen. In contrast, [[CV]] is a proton pump that utilizes the energy of proton flow along the protonmotive force to drive phosphorylation of [[ADP]] to [[ATP]]. | ||
}} | }} | ||
{{MitoPedia methods | {{MitoPedia methods | ||
|mitopedia method=Respirometry | |mitopedia method=Respirometry | ||
}} | }} | ||
{{MitoPedia O2k and high-resolution respirometry|type=Enzyme | {{MitoPedia O2k and high-resolution respirometry|type=Enzyme | ||
}} | }} | ||
{{Labeling | {{Labeling | ||
|discipline=Mitochondrial Physiology | |discipline=Mitochondrial Physiology | ||
|enzymes=Complex I, Complex II;succinate dehydrogenase, | |enzymes=Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase | ||
}} | }} | ||
Revision as of 10:12, 9 September 2018
- high-resolution terminology - matching measurements at high-resolution
Proton pump
Description
Mitochondrial proton pumps are large enzyme complexes (CI, CII, CIV, CV) spanning the inner mt-membrane, partially encoded by mtDNA. CI, CII and CIV are proton pumps that drive protons against the electrochemical protonmotive force, driven by electron transfer from reduced substrates to oxygen. In contrast, CV is a proton pump that utilizes the energy of proton flow along the protonmotive force to drive phosphorylation of ADP to ATP.
MitoPedia methods:
Respirometry
Labels:
Enzyme: Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase
