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• ET-excess capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• E-P excess capacity
  ...acity of the [[phosphorylation system]] exerts a limiting effect on OXPHOS capacity. In addition, ''E-P'' depends on coupling efficiency, since ''P'' aproaches ::::* Expand Bioblast links to '''''E-P'' excess capacity'''
  774 bytes (96 words) - 01:33, 31 December 2020
• Excess E-R capacity
  #REDIRECT [[E-R reserve capacity]]
  34 bytes (4 words) - 01:36, 12 November 2020
• Excess E-P capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• E-P excess ET capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:29, 12 November 2020
• ETS excess capacity, E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• Excess ETS capacity, E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• Excess ETS capacity factor over P
  36 bytes (4 words) - 02:05, 12 November 2020
• ETS excess capacity factor over P
  36 bytes (4 words) - 02:05, 12 November 2020
• ETS excess capacity, E-R
  #REDIRECT [[E-R reserve capacity]]
  34 bytes (4 words) - 01:36, 12 November 2020
• O2k-Publications: Threshold;excess capacity
  ...cations]] [[Instrument and method::Oxygraph-2k]] [[Topic::Threshold;excess capacity]] == O2k-Publications: Threshold;excess capacity - Abstracts ==
  1 KB (184 words) - 16:02, 16 April 2018
• ET-excess capacity E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• Excess E-R capacity factor
  36 bytes (4 words) - 02:16, 12 November 2020
• Excess E-P capacity factor
  36 bytes (4 words) - 02:05, 12 November 2020

Page text matches

• E-P excess capacity
  ...acity of the [[phosphorylation system]] exerts a limiting effect on OXPHOS capacity. In addition, ''E-P'' depends on coupling efficiency, since ''P'' aproaches ::::* Expand Bioblast links to '''''E-P'' excess capacity'''
  774 bytes (96 words) - 01:33, 31 December 2020
• E-P excess ET capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:29, 12 November 2020
• ET-excess capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• ETS excess capacity, E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• Excess ETS capacity, E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:32, 12 November 2020
• ET-excess capacity E-P
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• Excess E-P capacity
  #REDIRECT [[E-P excess capacity]]
  33 bytes (4 words) - 01:31, 12 November 2020
• O2k-Publications: Threshold;excess capacity
  ...cations]] [[Instrument and method::Oxygraph-2k]] [[Topic::Threshold;excess capacity]] == O2k-Publications: Threshold;excess capacity - Abstracts ==
  1 KB (184 words) - 16:02, 16 April 2018
• E-R control efficiency
  ...ation. Similarly, the apparent [[E-P excess ET capacity |''E-P'' excess ET capacity]] is not a respiratory reserve in the sense of oxidative phosphorylation.
  1 KB (193 words) - 16:32, 13 December 2023
• E-P control efficiency
  ...oupler]] titration, which yields the [[E-P excess capacity |''E-P'' excess capacity]].
  2 KB (288 words) - 18:29, 1 January 2021
• MitoPedia: Respiratory states
  [[File:EPL-net and excess.jpg|right|300px|thumb|[[Gnaiger 2020 BEC MitoPathways |MitoPathways 2020: F ...OUTINE respiration|ROUTINE-respiration]] [[Image:E.jpg|link=ET capacity|ET capacity]] [[Image:L.jpg|link=LEAK respiration|LEAK respiration]] - [[Image:ROX.jpg|
  2 KB (243 words) - 08:37, 25 November 2023
• Biochemical coupling efficiency
  ...L'')/''P'' = 1-''L/P'', only at zero [[E-P excess capacity |''E-P'' excess capacity]], when ''P'' = ''E''). The biochemical coupling efficiency is independent
  901 bytes (110 words) - 01:27, 31 December 2020
• MitoPedia: Respiratory control ratios
  [[File:EPL-net and excess.jpg|right|300px|thumb|[[Gnaiger 2020 BEC MitoPathways |MitoPatwhays 2020]]] ...r]] [[Image:jExR.jpg|50 px|link=Excess E-R capacity factor |Excess ''E-R'' capacity factor]]
  2 KB (309 words) - 11:37, 22 March 2022
• Gnaiger 2002 Biochem Soc Trans
  ...ome ''c'', which suggests a direct functional role for the apparent excess capacity of cytochrome ''c'' oxidase in hypoxia and under conditions of intracellula |topics=Cyt c, Flux control, Oxygen kinetics, Threshold;excess capacity
  3 KB (341 words) - 21:23, 27 March 2023
• Garedew 2006 Biochim Biophys Acta
  ...Lemieux H, Schachner T, Blier PU, Tardif J-C, Gnaiger E (2006) High excess capacity of cytochrome ''c'' oxidase in permeabilized fibers of the mouse heart. Bio ...iological temperature of 37 °C with caution only. The very high COX excess capacity under hypothermia (4 °C) may compensate for hypothermic hypoxia by decreas
  3 KB (510 words) - 18:14, 10 January 2022
• Groeger 2012 Shock
  ...und at low temperatures. In macrophage-derived cell lines, both the excess capacity of CIV and the efficiency of sulfide elimination may increase at low temper |topics=Temperature, Threshold;excess capacity
  3 KB (382 words) - 17:29, 4 June 2017
• Kudin 2002 Mol Biol Rep
  ...lhaber S, Elger CE, Kunz WS (2002) Differences in flux control and reserve capacity of cytochrome c oxidase (COX) in human skeletal muscle and brain suggest di ..., a flux control coefficient of COX of 0.12±0.05 and a 3.9±0.6-fold excess capacity of the enzyme. The observed difference in metabolic control can be attribut
  2 KB (243 words) - 15:48, 24 March 2015
• Madlala 2019 Integr Food Nutr Metab
  ...ibits GOT activity, reduced mitochondrial leak respiration, OXPHOS and ETS capacity. These changes were observed with complex-1 linked respiration (substrates
  2 KB (228 words) - 16:01, 30 January 2020
• Groeger 2010 Crit Care
  ...sought to determine the effect of hypothermia on mitochondrial respiratory capacity and H₂S-related COX inhibition. We further studied the influence ...ective stimulation of CIV after addition of ascorbate and TMPD. COX excess capacity (% of ET-pathway) was calculated based on the ratio of inhibition of mitoch
  3 KB (463 words) - 14:26, 13 November 2017
• Gnaiger 1998 BTK-COX
  ...1998) Functional interpretation of the flux control coefficient and excess capacity of cytochrome c oxidase at intracellular oxygen. In BioThermo-Kinetics in t ...racellular oxygen pressure, and (ii) proposing a functional role of excess capacity of cytochrome ''c'' oxidase in terms of “synkinetic” regulation of high
  3 KB (350 words) - 04:26, 23 November 2021
• Gnaiger 2023 MiP2023
  ...ards pre-obesity (overweight). The BME is linearly related to the body fat excess in women and men with statistical implications on mitochondrial functional ...mass ''V''_{O₂max/''M''} and mitochondrial respiratory capacity per muscle mass [1] decline as a function of BME. Compromised mitochondrial
  3 KB (407 words) - 13:50, 17 July 2023
• Cardinale 2018 Acta Physiol (Oxf)
  ...> were measured ''ex vivo'' in isolated mitochondria. Mitochondrial excess capacity in the leg was determined from OXPHOS in permeabilized fibres and muscle ma ...ant relationship between O₂ extraction and mitochondrial excess capacity and p50_mito that was unrelated to blood flow and mean transit ti
  3 KB (407 words) - 13:40, 22 May 2022
• Kunz 2000 J Biol Chem
  ...49 % of their mitochondrial DNA, revealed a substantially lowered reserve capacity and increased flux control coefficient of COX, indicating severe rate limit
  2 KB (282 words) - 17:23, 16 January 2021
• Hyphenation
  ::::* [[OXPHOS capacity]], but: [[OXPHOS-coupling efficiency]] ::::* [[Phosphorylation pathway]], but: Phosphorylation-pathway capacity
  4 KB (469 words) - 02:31, 23 January 2023
• Gnaiger 1998 J Exp Biol
  ...(1998) Mitochondrial oxygen affinity, respiratory flux control, and excess capacity of cytochrome ''c'' oxidase. https://doi.org/10.1242/jeb.201.8.1129 ...ulation of oxygen affinity provides a functional explanation of the excess capacity of COX. The concept of symmorphosis, a matching of capacities in the respir
  4 KB (588 words) - 16:42, 24 April 2023
• Villani 1998 J Biol Chem
  ...Greco M, Papa S, Attardi G (1998) Low reserve of cytochrome ''c'' oxidase capacity ''in vivo'' in the respiratory chain of a variety of human cell types. J Bi ...abilized cells have revealed a CIV capacity that is nearly limiting (7-22% excess) for ADP + glutamate/malate-dependent respiration. The present observations
  3 KB (386 words) - 18:06, 16 January 2021
• Additive effect of convergent electron flow
  ...es not limit OXPHOS capacity ([[Excess E-P capacity factor |excess ''E-P'' capacity factor]] is zero). In most cases, however, additivity is incomplete, NS < N
  3 KB (428 words) - 15:34, 31 January 2024
• Level flow
  |description=[[File:E.jpg |link=ET capacity]] '''Level flow''' is a [[steady state]] of a system with an input process ...i) supported by an excess of defined reduced substrates, which is [[OXPHOS capacity]], ''P'', at minimum levels of ATP (to maintain the output force or Gibbs f
  2 KB (307 words) - 15:00, 8 June 2020
• P/E control ratio
  ...separate the kinetic effect of ADP limitation from limitation by enzymatic capacity at saturating ADP concentration. ...|coupling]] of [[OXPHOS]], but mainly results from a diversity in the [[ET-excess control efficiency E-P]] in different species, tissues and cell lines.
  4 KB (623 words) - 01:14, 31 December 2020
• Gnaiger 2020 PaduaMuscleDays
  |title=Gnaiger E (2020) Body mass excess, muscle mass, obesity and mitochondrial fitness. PaduaMuscleDays. ...s of ergometric fitness is due to the decline of mitochondrial respiratory capacity per muscle mass, ''m''_M [2,3], as a function of BME. Yet this mo
  4 KB (573 words) - 23:27, 23 February 2020
• N/S pathway control ratio
  ...'E''</sub> ~ 2 in the ET-state (high [[E-P excess capacity |''E-P'' excess capacity]] specifically for the N-pathway). In contrast, N_''E''/S_{''E
  2 KB (300 words) - 19:14, 30 December 2020
• Bioblast alert 2015
  ...INE]] - [[Image:L.jpg|link=LEAK respiration|LEAK]] - [[Image:E.jpg|link=ET capacity|ETS]] - [[Image:ROX.jpg|link=Residual oxygen consumption|ROX]]: this is the ...' capacity]] [[Image:ExR.jpg|60 px|link=Excess E-R capacity|Excess ''E-R'' capacity]]
  4 KB (560 words) - 15:01, 8 June 2020
• Kake-Guena 2017 J Therm Biol
  ...and complex IV substrates relative to the maximal oxidative phoshorylation capacity of mitochondria. More importantly, some of the clonal divergences were only |topics=Threshold;excess capacity
  2 KB (336 words) - 10:34, 5 March 2018
• Maarman 2016 J Appl Physiol (1985)
  ...tration of 10 nM may be a possible therapy against some adverse effects of excess uric acid.
  3 KB (363 words) - 14:36, 23 February 2021
• Mandic 2022 J Comp Physiol B
  ...hese results demonstrate species-specific differences in cardiac metabolic capacity, which may influence the acclimation potential of notothenioid fishes to ch |keywords=Metabolic capacity, Mitochondrial function, Notothenioids, Ontogeny, Oxidative phosphorylation
  3 KB (356 words) - 19:23, 24 February 2023
• Uhmeyer 2017 Plant Physiol
  ...oplast stroma, which is caused by an increased mitochondrial electron sink capacity. Increased susceptibility to photoinhibition of PSII in stm6 demonstrates t
  2 KB (232 words) - 16:07, 8 August 2023
• Boushel 2013 Abstract MiP2013
  ...th variable enhancement of mitochondrial OXPHOS capacity, which remains in excess to maximize the ''p''_O2 gradient from the red blood cell to cyto ...is C, Sondergaard H, Ara I, Helge JW, Saltin B (2011) Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion 11:303-7.]]
  3 KB (422 words) - 11:10, 28 April 2017
• Gnaiger 2020 APS Chicago
  |title=Gnaiger E (2020) Aerobic exercise capacity and mitochondrial fitness: from muscle to brain. APS2020 Chicago. |abstract=Body mass excess accumulated in sedentary lifestyles leads to deceleration of running speed.
  1,004 bytes (123 words) - 15:03, 26 February 2020
• Pichaud 2013 J Bioenerg Biomembr
  2 KB (335 words) - 11:04, 23 June 2022
• Moyes 1992 Am J Physiol
  ...e mitochondria operate at a small fraction of their in vitro maximum. This capacity is suppressed in vivo by highly inhibitory ATP/ADP and limiting phosphate. |topics=ADP, ATP, Flux control, PCr;Cr, Phosphate, Threshold;excess capacity
  2 KB (333 words) - 09:12, 9 November 2016
• Biochemical threshold effect
  ...d a linear slope is obtained, which is extrapolated to the apparent excess capacity of the single step. The physiological threshold is overestimated for N-path
  876 bytes (125 words) - 19:45, 1 January 2021
• Meszaros 2017 MiP2017
  ...ensitive diagnostic tool to determine apparent cytochrome c oxidase excess capacity. ...cols and cyanide titration is needed to obtain precise data for COX excess capacity. Therefore, our goal was to assess mitochondrial oxygen kinetics as an alte
  5 KB (718 words) - 18:53, 10 January 2022
• State 3
  ...ations applied in State 3 are not necessarily saturating, whereas [[OXPHOS capacity]] is measured at saturating concentrations of ADP and P_i (OXPHOS ...underestimation of [[OXPHOS capacity]] and overestimation of [[excess E-P capacity]].
  3 KB (449 words) - 18:46, 1 January 2021
• No 2020 Pflugers Arch
  ...ning ameliorated the aging-induced imbalance in mitochondrial dynamics and excess mitophagy. Aging induced increase in Bax and cleaved caspase-3 protein leve
  3 KB (414 words) - 06:13, 20 April 2020
• Pichaud 2010 J Exp Biol
  ...nthase, cytochrome c oxidase (COX), catalase and aconitase, and the excess capacity of COX at high convergent pathway flux were also measured as a function of ...l regulation probably varies with temperature. For example, the excess COX capacity is low, even non-existent, at high and intermediate temperatures (18 °C, 2
  3 KB (393 words) - 11:05, 23 June 2022
• Gnaiger 1998 Biochim Biophys Acta
  ...''J''max/''p''₅₀. High oxygen affinity is achieved by an excess capacity of cytochrome ''c'' oxidase relative to the Electron transfer-pathway and a ...* [[State 3]] is measured at high [ADP] close to saturated [ADP] ([[OXPHOS capacity]]) in the presence of added ATP.
  4 KB (505 words) - 16:27, 24 April 2023
• Gnaiger 2017 MiPschool C1
  |title=[[File:Gnaiger Erich.jpg|left|90px]] Apparent Complex IV excess capacity and biochemical thresholds. ..., Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in perm
  2 KB (205 words) - 12:34, 3 November 2018
• Pint of Science 2023 Innsbruck AT
  ...ired by the power plants of the cells: the mitochondria. Their respiratory capacity decreases with obesity. Obesity is the leading cause of death and premature :::: '''[[Gnaiger Erich |Erich Gnaiger]]: Body mass excess and decline of mitochondrial fitness'''
  3 KB (322 words) - 16:40, 4 June 2023
• Bovard 2018 IOC134
  ...gen delivery to working muscle, the adaptive responses of muscle oxidative capacity and therefore mitochondrial contributions are not fully understood. Moreove ...nclude muscle mass-normalized O₂ delivery, mitochondrial excess capacity, relative activation of mitochondria, and the role of p50 in O₂
  4 KB (487 words) - 11:15, 17 September 2018
• Oliveira 2022 Abstract Bioblast-Aedes
  ...ons were observed in proline and [[E-P excess capacity |''E''-''P'' excess capacity]] 24 h upon zymosan injection, this effect was not correlated to the magnit
  4 KB (602 words) - 08:32, 28 July 2022
• Cardinale 2018 Thesis
  ...this overcapacity. Little is known about the role of this excess oxidative capacity of mitochondria in regulating oxygen consumption, the role of oxygen delive ...nd that the major source of variation in measuring mitochondrial oxidative capacity is the sample preparation per se were shown. Furthermore, other factors suc
  6 KB (840 words) - 17:16, 7 March 2020
• Health Innovation Summit 2023 Vienna AT
  [[File:BMI gender data gap.png|right|400px|link=Body mass excess]] ...'': Cellular energy metabolism is fired by mitochondria. Their respiratory capacity decreases with obesity. But the WHO defines obesity with an adult-white-mal
  1 KB (169 words) - 14:59, 7 June 2023
• Risiglione 2022 Life (Basel)
  ...n flows devoted to ATP production while it reduces the bioenergetic excess capacity of mitochondria, providing a possible explanation of the increased cell sus
  2 KB (245 words) - 09:46, 9 June 2023
• Pichaud 2012 Comp Biochem Physiol A Mol Integr Physiol
  ...piration in permeabilized fibers of a marine invertebrate with low aerobic capacity. Comp Biochem Physiol A Mol Integr Physiol 161:429-35. ...der to inhibit Complex III. Moreover, the apparent Complex IV (CIV) excess capacity was evaluated using different substrates to assess the implication of this
  2 KB (280 words) - 11:04, 23 June 2022
• Burtscher J 2016 Abstract MitoFit Science Camp 2016
  ...st, CII-linked capacity was especially important in the striatum. Apparent excess capacities of the electron transfer-pathway (ET-pathway) over OXPHOS also d ...d to ET-capacity. Tissue-mass specific CI-linked oxygen consumption and ET-capacity remained decreased.
  3 KB (364 words) - 18:45, 10 January 2022
• Lemieux 2011 Abstract Bordeaux
  ...ux H, Semsroth S, Antretter H, Hoefer D, Gnaiger E (2011) Increased OXPHOS capacity after cold preservation of the human heart – a paradox resolved by a dysc ...conditions, the increase of respiration in the OXPHOS state at constant ET capacity indicates a mitochondrial dysfunction after cold preservation of human hear
  6 KB (874 words) - 18:21, 10 January 2022
• Shirihai 2014 Abstract MiP2014
  ...energy supply and relatively low ATP demand, such as beta-cells exposed to excess nutrients, induce mitochondrial fragmentation [6]. This raises the possibil ...on is associated with increased uncoupling and the enhanced consumption of excess nutrients, thereby serving as an adaptive mechanism.
  5 KB (648 words) - 10:41, 23 February 2015
• Lemieux 2019 bioRxiv
  ...ere was not even the slightest excess Complex IV capacity above NS-pathway capacity. In contrast, electron flow reached only 60% when supported by succinate al ...ng efficiency;uncoupling, Cyt c, Flux control, Inhibitor, Threshold;excess capacity, Uncoupler, Q-junction effect
  3 KB (477 words) - 11:08, 27 November 2021
• Gnaiger 2011 Abstract-MonteVerita
  |title=Gnaiger E (2011) Mitochondrial respiratory capacity at maximum aerobic exercise levels: Are intracellular oxygen levels limitin |abstract='''Mitochondrial capacity''': [[OXPHOS]] capacity is evaluated in isolated mitochondria (mt) and permeabilized cells with phy
  3 KB (393 words) - 18:20, 10 January 2022
• Chowdhury 2012 Brain
  ...elopment of distal axonopathy in diabetic neuropathy is linked to nutrient excess and mitochondrial dysfunction via defective signalling of the adenosine mon |topics=AMP, Substrate, Threshold;excess capacity
  3 KB (422 words) - 08:23, 21 February 2020
• Matarne 2015 Abstract MiPschool Greenville 2015
  |title=Chronic activation of AMP-activated protein kinase increases oxidative capacity and monocarboxylate transporter expression in skeletal muscle of pigs. ...a indicate that chronic AMPK activation simultaneously increases oxidative capacity and MCT2 and MCT4 expression in porcine skeletal muscle, which contributes
  3 KB (458 words) - 15:22, 20 July 2015
• Boushel 2011 Mitochondrion
  ...is C, Sondergaard H, Ara I, Helge JW, Saltin B (2011) Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion 11:303-7. ...capacity surpasses ''in vivo'' ''V''O(2)max. The findings reveal an excess capacity of muscle mitochondrial respiratory rate over O(2) delivery by the circulat
  3 KB (409 words) - 13:13, 27 December 2021
• Villani 1997 Proc Natl Acad Sci U S A
  ...e observed relationship between COX respiratory threshold and relative COX capacity and the potential extension of the present analysis to other respiratory co
  2 KB (360 words) - 03:18, 24 August 2021
• Lemieux 2017 Sci Rep
  ..., Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in perm ...parent excess capacity of cytochrome c oxidase above physiological pathway capacity increased sharply under hypothermia due to limitation by NADH-linked dehydr
  4 KB (595 words) - 09:34, 30 November 2023
• P-L control efficiency
  ...L}'' = 0.0 (RCR=1) for a system with zero respiratory phosphorylation capacity (''P-L''=0) or zero [[E-L coupling efficiency |''E-L'' coupling efficiency] ...ergometry), cell ergometry is based on OXPHOS analysis to determine OXPHOS capacity, ''J''_O₂''P''=''P'' [pmol O₂·s<sup>-1</su
  9 KB (1,431 words) - 20:35, 19 March 2022
• Jones 2010 Biochim Biophys Acta
  ...ed deficiencies in Complex I endogenous substrate availability and reserve capacity of Complex IV in cortical neuron electron transport. Biochim Biophys Acta 1 ...ndogenous substrate availability. The greatest age-related deficit in flux capacity occurred at Complex IV with a 29% decrease in neurons isolated from 24-mont
  2 KB (304 words) - 14:38, 20 March 2015
• Complex IV
  ...d in different coupling states ([[LEAK|''L'']], [[OXPHOS|''P'']], and [[ET-capacity|''E'']]). Since CIV is a [[proton pump]] of the [[electron transfer system] ...djusted to obtain a reaction velocity corresponding to the apparent excess capacity ([[Gnaiger_1998_J Exp Biol]]).
  5 KB (663 words) - 13:23, 5 March 2021
• Eshima 2020 J Appl Physiol (1985)
  ...in body composition, lean mass, individual muscle masses, force-generating capacity, and muscle fiber cross-sectional area. These data suggest that neutralizin
  2 KB (286 words) - 21:43, 20 August 2020
• Gnaiger 2014 Abstract MiP2014
  ...his is metabolically opposite to uncoupling respiration, which yields [[ET-capacity]]. The OXPHOS state can be established experimentally by selective [[perme ...treadmill, cell ergometry is based on OXPHOS analysis to determine OXPHOS capacity, ''J''_O2P=''P'' [pmol O2·s^-1·mg^-1], at t
  8 KB (1,273 words) - 18:16, 7 November 2020
• Scott 2009 Am J Physiol Regul Integr Comp Physiol
  ...had a higher mass-specific aerobic capacity. This may represent a surplus capacity that counteracts the depressive effects of hypoxia on mitochondrial respira
  3 KB (380 words) - 06:57, 28 July 2023
• Lemieux 2006 Biochim Biophys Acta
  ...er PU, Tardif J-C, Gnaiger E (2006) Temperature effects on the control and capacity of mitochondrial respiration in permeabilized fibers of the mouse heart. Bi ...ity. These results show that (1) malate+glutamate underestimates complex I capacity by 40 % at physiological temperature, and pyruvate should be added; (2) dia
  3 KB (453 words) - 18:14, 10 January 2022
• Cell ergometry
  ...ations are applied to determine the apparent ET-pathway excess over OXPHOS capacity ([[E-P control efficiency |''E-P'' control efficiency) and to calculate the
  3 KB (459 words) - 01:26, 31 December 2020
• Naimi 2011 Clin Physiol Funct Imaging
  ...6·33 versus control 95·73 ± 6·53 pmol s(-1) mg tissue(-1) ); (iii) excess capacity of [[Complex_IV|cytochrome c oxidase]] in COPD patients was only ~50% that
  2 KB (300 words) - 05:23, 8 February 2020
• Kake 2017 J Therm Biol
  ...and complex IV substrates relative to the maximal oxidative phoshorylation capacity of mitochondria. More importantly, some of the clonal divergences were only
  2 KB (336 words) - 13:34, 5 June 2018
• Stephenson 2012 Am J Physiol Endocrinol Metab
  ...Lee JS, Kosari S, Hawley JA, Stepto NK (2012) Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet. Am J Physiol Endo ...the respiratory capacity of skeletal muscle is enhanced in response to the excess energy supplied by a WD. This is likely due to an increase in mitochondrial
  3 KB (383 words) - 16:11, 13 November 2017
• Gemmink 2016 Diabetologia
  ...LDs, not by LDs devoid of PLIN5. Also the association between IMCL storage capacity and insulin resistance and mitochondrial dysfunction was only apparent for ...in subcellular redistribution of PLIN5 and promotes the capacity to store excess fat in larger and more numerous PLIN5-decorated LDs. This associates with b
  3 KB (346 words) - 14:19, 13 November 2017
• Gnaiger 2015 Abstract MiPschool Cape Town 2015 II
  ...ermeabilized while maintaining mitochondria intact for the study of OXPHOS capacity, which provides a model for biochemical cell ergometry [3]. ...m. Therefore, ''E''-''R'' in general is not a respiratory reserve or spare capacity for phosphorylation.
  13 KB (2,089 words) - 18:19, 7 November 2020
• Obesity
  ...hondrial capacity. Body fat excess, therefore, correlates with [[body mass excess]] up to a critical stage of obesogenic lifestyle-induced [[sarcopenia]], wh |info=[[Haslam 2007 Obes Rev]], [[Body mass excess]]
  6 KB (867 words) - 00:35, 15 February 2020
• Favier 1995 J Appl Physiol (1985)
  ...and 3) training in normoxia in these subjects results in a reduced buffer capacity.
  3 KB (367 words) - 20:30, 16 December 2021
• Body fat excess
  ...ht of humans |height]]. Importantly, body fat excess, BFE, and [[body mass excess]], BME, are linearly related, which is not the case for the body mass index |info=[[Body mass excess]]
  19 KB (3,070 words) - 10:28, 5 June 2023
• Nagy 2014 Abstract MiP2014
  ...iration]] was increased; furthermore, glutamine increased the [[Excess E-R capacity factor |scope of uncoupler-stimulated respiration]] above ROUTINE activity ...erpreting the ECAR results, we claim that these cells show high glycolytic capacity. Furthermore, we found that, besides glucose, glutamine was the most prefer
  3 KB (403 words) - 13:04, 23 January 2019
• Evinova 2018 MiP2018
  ...). We did not observe the statistic significant difference in the coupling capacity using higher or lower concentration of oligomycin. |topics=Threshold;excess capacity
  3 KB (461 words) - 00:17, 18 March 2019
• Gnaiger 2018 MiPschool Tromso A1
  ...[[supercomplex]] assemblies [4], and leads to a re-evaluation of apparent excess capacities of CIV [5]. ...E'', which are equivalent only at an [[Excess E-P capacity |excess ''E-P'' capacity]] equal to zero (''ExP'' = ''E-P'' = 0) (Figure 2 [4]).
  10 KB (1,441 words) - 23:46, 25 January 2021
• Funk 2015 Abstract MiPschool Greenville 2015
  ...n contrast, the opposite is observed in bovine (b) GH transgenic mice with excess GH. These mice have high levels of IGF-1 and are giant and lean, with impai ...of isolated mitochondria. Further investigation may reveal how the aerobic capacity of the entire organism is altered as a function of GH action, which may ult
  3 KB (415 words) - 08:38, 21 July 2015
• Kuznetsov 2004 Am J Physiol Heart Circ Physiol
  ...ut not cold ischemia alone resulted in the loss of NADH-linked respiratory capacity, uncoupling of oxidative phosphorylation and Cyt ''c'' release. Mitochondri |topics=Coupling efficiency;uncoupling, Cyt c, Flux control, Threshold;excess capacity
  3 KB (377 words) - 14:01, 27 December 2021
• Kang 2018 Exp Mol Med
  ...act=An excess of reactive oxygen species (ROS) relative to the antioxidant capacity causes oxidative stress, which plays a role in the development of Parkinson
  2 KB (268 words) - 17:23, 25 February 2020
• Janssens 2015 Nutr Metab (Lond)
  |abstract=Excess consumption of energy-dense, high-fat Western diets contributes to the deve ...very-low density lipoprotein (VLDL) secretion and ''ex vivo'' respiratory capacity of liver mitochondria using fat-derived substrates. In addition, whole-body
  3 KB (406 words) - 17:40, 7 November 2016
• MiPNet08.09 CellRespiration
  ...atio, net''R''=(''R-L'')/''E'' was 0.30, indicating that 30% of ET-pathway capacity was activated for ATP production. ...Image:L.jpg|link=LEAK respiration|LEAK]] [[Image:E.jpg|link=ET capacity|ET capacity]] [[Image:ROX.jpg|link=Residual oxygen consumption|ROX]]
  5 KB (738 words) - 14:52, 8 June 2020
• Bonsignore 2015 Mech Ageing Dev
  ...d mitochondrial function may benefit Nrmt1(-/-) mice and protect them from excess internal ROS and subsequent DNA damage. These studies position the NRMT1 kn
  2 KB (299 words) - 16:59, 9 November 2017
• Kunz 1995 Biochem Mol Med
  |topics=ADP, Threshold;excess capacity
  2 KB (280 words) - 14:07, 27 March 2015
• Lemieux 2017 bioRxiv 103457
  ..., Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in perm ...er PU, Tardif J-C, Gnaiger E (2006) Temperature effects on the control and capacity of mitochondrial respiration in permeabilized fibers of the mouse heart. Bi
  4 KB (513 words) - 18:56, 22 May 2019
• Reynolds 2004 Physiol Biochem Zool
  ...ction on mitochondrial respiration appears to be due to the 31% excess COX capacity in ''A. franciscana'' mitochondria. Transmission electron micrographs of em
  2 KB (314 words) - 09:45, 9 November 2016
• Petroutsos 2016 Nature
  ...values beyond the capacity of photosynthetic CO₂ assimilation. Excess light may cause oxidative damage and cell death, processes prevented by enh
  2 KB (295 words) - 14:36, 21 March 2023
• Hoene 2021 Mol Metab
  ...iver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. Mol Metab 54:101359. ...keletal muscle, the combination of HED and training improved the oxidative capacity to a greater extent than training alone by increasing respiration of isolat
  3 KB (427 words) - 17:18, 22 February 2022
• Mourier 2014 Hum Mol Genet
  |topics=Threshold;excess capacity
  2 KB (298 words) - 15:27, 13 November 2017
• Gnaiger 2019 MiP2019
  ...|66px|Erich Gnaiger]] OXPHOS capacity in human muscle tissue and body mass excess – the MitoEAGLE mission towards an integrative database (Version 6; 2020- ...ization of datasets published by different research laboratories on OXPHOS capacity in isolated mitochondria and permeabilized fibers obtained from biopsies of
  13 KB (1,952 words) - 19:12, 10 January 2022
• Vielhaber 2000 Biochem Soc Trans
  |topics=Flux control, Threshold;excess capacity
  2 KB (311 words) - 15:44, 19 February 2015
• ET capacity
  ...juries or toxic effects of pharmacological or environmental substances. ET capacity in mitochondrial preparations requires the addition of defined fuel substra » [[#Why ET capacity, why not State 3u.3F | '''MiPNet article''']]
  11 KB (1,488 words) - 20:30, 19 March 2022
• Kuznetsov 1996 J Biol Chem
  |topics=Threshold;excess capacity
  2 KB (312 words) - 17:23, 16 January 2021

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