Acuna-Castroviejo D

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MiPsociety
COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


 

Acuna-Castroviejo D


MitoPedia topics: EAGLE 

COST: Member

COST WG2: WG2


COST Mentor: Mentor

MC Substitute - Management Committee MitoEAGLE


Name Acuna-Castroviejo Dario, Professor of Physiology

ORCID ID

Institution
Dario Acuna-Castroviejo

Biomedical Research Center,

Health Science Technology Park,

University of Granada, ES

Address Avenida del Conocimiento, s/n, 18016
City Armilla (Granada)
State/Province
Country Spain
Email dacuna@ugr.es
Weblink Centro de Investigación Biomédica

http://www.iimel.es/

O2k-Network Lab ES Granada Acuna-Castroviejo D


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Publications

 PublishedReference
Gnaiger 2019 MitoFit Preprint Arch2019Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v6.
Chabi 2019 MitoFit Preprint Arch EA2019Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. MitoFit Preprint Arch doi:10.26124/mitofit:ea19.MitoEAGLE.0001.
Lopez 2017 PLOS ONE2017López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.
Doerrier 2016 Mitochondrion2016Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Volt 2016 J Pineal Res2016Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
García-Corzo 2015 Biochim Biophys Acta2015García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Garcia 2015 FASEB J2015García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
Acuña-Castroviejo 2014 Cell Mol Life Sci2014Acuña-Castroviejo D, Escames G, Venegas C, Díaz-Casado ME, Lima-Cabello E, López LC, Rosales-Corral S, Tan DX, Reiter RJ (2014) Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci 71:2997-25.
Ortiz 2014 J Pineal Res2014Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Escames 2013 Horm Mol Biol Clin Investig2013Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Garcia-Corzo 2013 Hum Mol Genet2013García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Concepcion-Huertas 2013 J Sports Sci2013Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Acuña-Castroviejo 2012 Age (Dordr)2012Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.
Lopez 2009 J Pineal Res2009López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98.

Abstracts

 PublishedReference
Garcia-Roves 2019 MiPschool Coimbra2019
Pablo Garcia-Roves
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Chabi 2019 MiP20192019
Béatrice Chabi
Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Garcia-Roves 2018 MiP2018b2018
Pablo Garcia-Roves
Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
Acuna-Castroviejo 2018 MiP20182018
Dario Acuna-Castroviejo
Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation
Escames 2018 MiP20182018
Germaine Escames
Suppression of AKT/mTOR pathway and activation of mitophagy by melatonin via mitocondrial regulation in head and neck cancer. Escames_Presentation
Garcia 2014 Abstract SECF2014Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF2014Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit2014Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Doerrier 2014 Abstract SECF2014Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Luna-Sánchez 2014 Abstract SECF2014Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF2014Experimental basis for the “inflammaging” theory.
Ortiz 2013 Abstract SEOR2013Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Luna-Sánchez 2012 Abstract FEPS&SECF2012CoQ deficiency: Molecular and pathophysiological consequences.
Acuna-Castroviejo 2012 Abstract Bioblast2012Acuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12.
Escames 2012 Abstract ESTRO2012Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Doerrier 2012 Abstract Bioblast2012Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge2012CoQ deficiency: molecular and phathophysiological consequences.
Garcia-Corzo 2011 Abstract Euromit 82011Generation of a mouse model of Coenzyme Q deficiency.
Escames 2011 Abstract FASEB Summer Research Conference2011Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.




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