MiP2018/MitoEAGLE Jurmala LV

MiP2018/MitoEAGLE Jurmala LV

Jurmala LV, 18-21 Sep 2018. 13th Conference on Mitochondrial Physiology: The role of mitochondria in health, disease and drug discovery - COST MitoEAGLE perspectives and MitoEAGLE WG and MC Meeting.

» Mitochondrial Physiology Society

Mitochondrial Physiology Society (2018-09-18) MitoGlobal

Abstract: 13^th Conference on Mitochondrial Physiology and MitoEAGLE WG and MC Meeting, 2018, Jurmala, Latvia.

Minutes MitoEAGLE Jurmala 2018

- Minutes prepared by Verena Laner and Marija Beno.

Find the WG summaries in the Minutes and also here

Venue

Conference room: Panorama, 10th floor

Hotel SemaraH Hotel Lielupe SPA

Bulduri prospect 64/68, Jurmala

Latvia

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  Conference room

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  Terrace

Hotel suggestion

The local organizer Makrecka-Kuka Marina has made pre-bookings for several twin rooms for the MiP2018/MitoEAGLE participants in the following hotel: SemaraH Hotel Lielupe SPA - which is also the conference venue.

Since the number of rooms is limited, we suggest to share rooms. When sending the registration mail, please include the information about how many nights you would like to stay (arrival and departure dates) and with whom you would like to share a room. We will book the room for you.

If you prefer to reserve your room personally - contact us and we will send you an information on how to do it and how to get the special flat rate (for single rooms only).

Programme

Instead of classical poster session, participants can present their work in poster-flash presentations during the conference

Programme »download pdf

Working Groups

WG1: MitoEAGLE protocols, terminology, documentation

• Final discussion of Gnaiger 2019 MitoFit Preprint Arch - All participants are invited to submit comments and improvements, and those who are not yet included as co-authors are invited to join.
• Mitochondrial respiratory control by fuel substrates and specific inhibitors of respiratory enzymes: Building blocks of mitochondrial physiology Part 2
• Training and knowledge management concept - MiPschool Tromso-Bergen 2018
• Towards a MitoEAGLE proficiency training workshop
• Report on ECI, ITC and gender balance in COST Action MitoEAGLE - Summary

WG2: MitoEAGLE data repository in skeletal and cardiac muscle

• Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers
• Inter-laboratory study on human permeabilized myofibres: effects of fibre preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation
• Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report

Summary WG2

Summary WG2 heart - extended version

WG3: MitoEAGLE data repository: adipose, liver, neuronal

• Coordination of collecting data - WG3 liver tissue

Summary WG3 Liver

Summary WG3 Fat

Summary WG3 Fat tissue

WG4: MitoEAGLE data repository for blood cells and cultured cells

• Update on MitoEAGLE blood cells 1 - A data manager will collect and analyze all data, in preparation of a database for Open Access in conjunction with the journal publication
• Effects of cryopreservation of peripheral blood mononuclear cells
• Integrating published data of mitochondrial function in cell lines as models of neurodegenerative disease
• Summary WG4

Social event

Excursion to Great Kemeri Bog

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Local organizer

Makrecka-Kuka Marina

Latvian Institute of Organic Synthesis

Invited speakers

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  Adams Sean H, PhD., University of Arkansas for Medical Sciences (UAMS), USA

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  Chicco Adam J, Prof., Colorado State University , USA

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  Dyson Alex, Dr., University College London, UK

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  Keller Markus A, Dr., Medical University of Innsbruck, AT

Registration

» Registration form for the MiP/MitoEAGLE conference

» Registration form for the MiP/MitoEAGLE conference and MC Meeting

Please send the filled out registration form to [email protected] with [email protected] in Cc.

Deadline: extended to 2018-Aug-03, COST support available for registrations received by 2018-Jul-27.

Abstracts

Send your abstract in the Abstract format to conference e-mail and to [email protected] in Cc. Submitted abstracts provide the basis for allocation of MitoEAGLE reimbursement.

• Format

Abstract format

Example: Doerrier 2017 Abstract MitoEAGLE Barcelona

Deadline: 2018-Aug-03

Abstracts/Participants - alphabetical order

  (Attendance list)

	Has title
Avram 2018 MiP2018	Cell-permeable succinate bypasses statin-induced mitochondrial complex I inhibition in human platelets. Avram_Presentation
Gorr 2018 MiP2018	Myoglobin outside of muscle: new roles of an "old protein".
Escames 2018 MiP2018	Suppression of AKT/mTOR pathway and activation of mitophagy by melatonin via mitocondrial regulation in head and neck cancer. Escames_Presentation
Acuna-Castroviejo 2018 MiP2018	Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation
Garcia-Roves 2018 MiP2018b	Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
Chinopoulos 2018 MiP2018	Exclusive neuronal expression of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation.
Adams 2018 MiP2018	Long-chain acylcarnitines: New perspectives on bioactivities and trafficking.
Carrageta 2018 MiP2018	Role of SIRT1 and SIRT3 in human sperm cells metabolism and bioenergetics.
Nehlin 2018 MiP2018	Aging biomarkers in multimorbidity patients. Nehlin_Presentation
Aral 2018 MiP2018	Effects of melatonin treatment on LETM1 silenced mouse embryonic fibroblast cells.
Arandarcikaite 2018 MiP2018	No abstract.
Arnould 2018 MiP2018a	Brucella-infected cells display a fragmentation of mitochondrial population: mechanisms and putative functional impact.
Arnould 2018 MiP2018b	A form of autophagy triggers lipolysis in 3T3-L1 adipocytes exposed to a mitochondrial uncoupling.
Wuest 2018 MiP2018b	The antibiotic doxycycline impairs cardiac mitochondrial and contractile function.
Bamberger 2018 MiP2018	Discovery and development of elamipretide: targeting mitochondrial dysfunction in rare and common disease.
Shabalina 2018 MiP2018	Elovl2-ablation leads to mitochondrial phospholipid remodeling and reduced oxidative phosphorylation capacity in mouse liver mitochondria.
Chakrabarti 2018 MiP2018	Fatty acid binding protein 3 regulation of mitochondrial lipids - A strategy for exceptional longevity in the Pipistrelle bat.
Keppner 2018 MiP2018	Effects of cryopreservation of peripheral blood mononuclear cells.
Bello 2018 MiP2018	No abstract.
Dubinin 2018 MiP2018	The effect of triclosan on the permeability of mitochondrial membranes and lecithin liposomes. Dubinin_Presentation
Belosludtsev 2018 MiP2018	Effect of bedaquiline and delamanid on the functions of rat liver mitochondria.
Chicco 2018 MiP2018b	Defective cardiolipin remodeling and cardiac mitochondrial dysfunction: supercomplexes or just complex?
Wuest 2018 MiP2018a	Reduction of acylcarnitines restores electrophysiological abnormalities in VLCAD deficient hiPSC-cardiomyocytes.
Porter 2018 MiP2018b	Skeletal muscle mitochondrial thermogenesis in hypermetabolic humans.
Porter 2018 MiP2018a	Evidence of functional uncoupling protein 1 in the white adipose tissue of hypermetabolic humans.
Kopitar-Jerala 2018 MiP2018	Cystatins, metabolism and neuro inflammation.
Tuncay 2018 MiP2018	Regulation of mitochondrial Zn2+ transporter ZIP7 effects sarco(endo)plasmic reticulum S(E)R-mitochondria coupling in hyperglycemia.
Schlattner 2018 MiP2018	Intramitochondrial nucleotide regeneration by NME/NDPK proteins – roles in mitochondrial dynamics, signaling and metastasis.
Petit 2018 MiP2018	Decreasing cytosolic translation is beneficial to yeast and human Tafazzin-deficient cells with dirupted mitochondrial homeostasis (Barth syndrome cell model).
Evinova 2018 MiP2018	High-resolution respirometry of neuroblastoma SH-SY 5Y cell line.
Villena 2018 MiP2018	Lack of MTERF4 in brown adipocytes impairs mtDNA-encoded protein translation and leads to brown adipose tissue thermogenic dysfunction.
Chicco 2018 MiP2018a	Maternal aging increases granulosa cell mitochondrial ROS release and reduces oocyte OXPHOS-linked respiration: implications for embryo development.
Casado Pinna 2018 MiP2018	No abstract.
Cervinkova 2018 MiP2018	Coordination of collecting data - WG3 liver tissue. Cervinkova_Presentation
Stankova 2018 MiP2018	Impact of western diet on energy metabolism in mouse liver.
Chabi 2018 MiP2018	No abstract.
Chicco 2018 MiP2018c	Role of mitochondria in skeletal muscle acclimatization to high-altitude.
Doerrier 2018 MiP2018c	Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation.
Cizmarova 2018 MiP2018	High-resolution respirometry of neuroblastoma SH-SY 5Y cell line.
Clemensson 2018 MiP2018	No abstract.
Nemec 2018 MiP2018	Aerobic/strength exercise intervention modulates skeletal muscle mitochondrial function in seniors.
Kuka 2018 MiP2018	The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.
Volska 2018 MiP2018	The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Makarova 2018 MiP2018	Plasma concentrations of fatty acids and acylcarnitines as biomarkers for diagnosis of insulin resistance in adipose and muscle tissues.
Dambrova 2018 MiP2018	L-Carnitine: from discovery to cardiometabolic risk markers.
Makrecka-Kuka 2018 MiP2018	Fatty acid oxidation in brain: from aging to ischemia and sepsis.
Stelfa 2018 MiP2018	Neuroprotective compound R-phenibut protects brain mitochondria against anoxia-reoxygenation damage in vitro.
Danhelovska 2018 MiP2018	The relevance of ACBD3 protein in energy metabolism in various cell lines. Danhelovska_Presentation
De Goede 2018 MiP2018	Timing of feeding behavior affects daily rhythms in body temperature and muscle mitochondrial metabolism.
Olgar 2018 MiP2018	Mitochondria-targeted antioxidants in aging related functional changes in the heart and aorta: MitoTEMPO improves aged-cardiovascular performance. Olgar_Presentation
Doerrier 2018 MiP2018a	Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.
Doerrier 2018 MiP2018b	Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Sobotka 2018 MiP2018	Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.
Dyson 2018 MiP2018	Therapeutic utility of sulphide donating thiometallates.
Gumeni 2018 MiP2018	Disruption of mitochondria dynamics induces proteome instability and promotes ageing.
Genova 2018 MiP2018	Respiratory supercomplexes: evidence for separate though interconnected compartments of Coenzyme Q10 in mammalian mitochondria.
Garcia-Roves 2018 MiP2018a	Mitochondrial signature and lifestyle modulation of metabolic plasticity.
Pereira da Silva Grilo da Silva 2018 MiP2018	The unspecific effect of etomoxir on mitochondrial respiration.
Gnaiger 2018 MiP2018	Mitochondrial respiratory control by fuel substrates and specific inhibitors of respiratory enzymes: Building blocks of mitochondrial physiology Part 2.
Votion 2018 MiP2018	Functional diagnosis of mitochondrial defects in equine atypical myopathy and targeted mitochondrial therapy: a preliminary study.
... further results

Impressions MiP2018 Jurmala

More pictures can be found here: https://files.fm/u/guynzexw & https://files.fm/u/6pc2ybsw

Pictures taken by the Local Organizers

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  Welcoming by Makrecka-Kuka Marina

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  The participants

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  Gnaiger Erich during some welcoming words

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  Invited speaker Chicco Adam J giving a lecture

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  Dambrova Maija presenting her work

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  WG2 leader Garcia-Roves Pablo M presenting at the MitoEAGLE/MiPConference

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  Invited speaker Adams Sean H

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  Doerrier Carolina presenting the WG2 progress

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  Excursion to Great Kemeri Bog

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  Participants enjoying the excursion

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  Walking through the bog

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  Kidere Dita during her presentation

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  The view on the sunset at the beatiful conference venue

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  WG4 Leader Moisoi Nicoleta

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  Nehlin Jan presenting

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  Snaphot of Chakrabarti Lisa

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  Chairs Dambrova Maija and Wuest Rob C

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  Invited speaker Dyson Alex

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  Turan Belma presenting her work

How to get there

By plane

Riga International Airport RIX.

From the Airport to the Conference Venue - the airport is located 15 km from the conference venue, however, there is no direct public transport from the Riga airport to Jurmala, thus there are 2 options to get to the conference venue:

• Option 1. By taxi - 15-20 min drive; 12-18 EUR depends on company (you can also use Taxify). Note that you have to be careful not to overpay for taxi. Recommended taxi companies are BalticTaxi (a light green car), RedCab (a white car with red roof) or using the app “Taxify”.

• Option 2. By public transport: Airport - Riga center - Jurmala. Take the bus No.22 at the Riga airport (stop Lidosta Riga; direction Abrenes iela) to the center of Riga (30 min) - exit at the stop Autoosta. (Alternative express minibus No.322 - exit at the stop Stacijas Laukums.) If you buy the ticket in a vending machine, the price is 1.15 EUR and if you buy the ticket from the bus driver, it is 2.00 EUR.

From there walk to the Riga Central station - it is a short-walking distance.

Take the train to the station Bulduri (30 min). Train directions: Riga-Sloka; Riga - Tukums 1 and 2; Riga - Dubulti.

The conference venue in 10-15 min walk from train station.

By coach

Riga International Coach Terminal. From Coach terminal to Conference Venue - take the train to Bulduri from Riga Central Station.

• Additional information:

Getting from/to The airport

Riga public transport

Train schedule and ticket information

Additional information

If you need any assistance to obtain visa to travel to Latvia, let us know how we can help you.

Information about Jurmala

Information about Riga

Financial support

COST MitoEAGLE reimbursement

1. Eligibility: Participants from Inclusivness Target Countries, Early career investigators and participants from all COST countries and International Partner Countries can apply - MitoEAGLE network.

2. Priority will be given to members of Inclusiveness Target Countries, to participants with specific presentations and to participants who will attend the entire event (Conference and Working Group Meeting).

3. Send your abstract in the Abstract format to conference e-mail and to [email protected] in Cc

Submitted abstracts provide the basis for allocation of MitoEAGLE reimbursement.

4. The COST MitoEAGLE reimbursement will cover the local costs (accommodation with 55€/night flat rate and meals with 20€ flat rate) and travel expenses.Registration fees can not be reimbursed.

     » Notification of MitoEAGLE reimbursement will be given until Aug 03rd. 

ITC Conference Grant

max of 5 participants will be awarded with the ITC Conference Grant.

Who can apply:Conference Grants are exclusively reserved for PhD students and ECI’s with a primary affiliation in an institution located in an ITC.

Task: The applicant must make an oral/poster presentation at the conference in question and must be listed in the official event/conference programme. The main subject of the oral presentation / poster presentation / speech at the approved conference must be on the topic of the Action and must acknowledge COST.

The participation of each applicant must be pre-approved by the Action MC.

How to apply

1. Register for the MiP2018/MitoEAGLE conference

2. Contact the local organizer with the wish to apply for the ITC Conference Grant

3. Send an abstract to [email protected] and to the local organizer

4. The decision will be made by the COST Action Chair and the local organizer

5. As soon as the decision was made you will receive an instruction on how to apply on COST

 Application deadline: will be announced soon    

Co-organized with COST Action MitoEAGLE: Management Committee Meeting and Working Group Meetings.

Labels:

ORO, 2018, MitoEAGLE, MiP, MitoGlobal 

Support

This project has received funding from the European Union's Horizon 2020 research and innovation programme supported by COST (European Cooperation in Science and Technology) under grant agreement No OC-2015-2-19984.

Listed under MitoGlobal Events.