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Difference between revisions of "Herminghaus 2014 Abstract MiP2014"

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|diseases=Sepsis
|diseases=Sepsis
|topics=ADP, Coupling efficiency;uncoupling, O2
|topics=ADP, Coupling efficiency;uncoupling, O2
|substratestates=CII, CIII
|couplingstates=LEAK, OXPHOS
|additional=MiP2014
|additional=MiP2014
}}
}}

Revision as of 09:23, 5 August 2014

Severity of polymicrobial sepsis modulates mitochondrial function in rat liver.

Link:

MiP2014, Book of Abstracts Open Access

Herminghaus A, Barthel F, Heinen A, Beck C, Vollmer C, Bauer I, Picker O (2014)

Event: MiP2014


Labels: MiParea: Respiration, mt-Medicine  Pathology: Sepsis  Stress:Mitochondrial Disease; Degenerative Disease and Defect"Mitochondrial Disease; Degenerative Disease and Defect" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property.  Organism: Rat  Tissue;cell: Liver  Preparation: Isolated Mitochondria"Isolated Mitochondria" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property.  Enzyme: Complex I, Complex II; Succinate Dehydrogenase"Complex II; Succinate Dehydrogenase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property.  Regulation: ADP, Coupling efficiency;uncoupling, O2"O2" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.  Coupling state: LEAK, OXPHOS 


MiP2014 

Affiliation

Dep Anesthesiology, Univ Hospital Duesseldorf, Germany. - [email protected]

means±SD RCI-G/M RCI-S ADP/O-G/M ADP/O-S
Control 8.7±3.03 6.2±1.97 3.3±1.10 2.7±1.27
SHAM 12.5±2.73 8.4±0.98 * 3.4±1.01 2.6±0.44
16G 15.2±2.87 * 9.6±0.95 * 3.5±0.68 2.8±0.57
14G 11.2±2.88# 7.8±0.88 3.3±0.52 2.4±0.27

(*P<0.05 vs control, #P<0.05 vs 16G)