Semantic search
From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Marrocco 2020 Thesis | 2020 | Marrocco A (2020) Alterations of CCSP expression and macrophages metabolism in the development of silica-induced pulmonary inflammation and fibrosis. PhD Thesis 108. | LEAK OXPHOS ET | S ROX | Intact cells | Mouse | Macrophage-derived |
Rocha 2020 Sci Adv | 2020 | Rocha AL, de Lima TI, de Souza GP, Corrêa RO, Ferrucci DL, Rodrigues B, Lopes-Ramos C, Nilsson D, Knittel TL, Castro PR, Fernandes MF, Dos Santos Martins F, Parmigiani RB, Silveira LR, Carvalho HF, Auwerx J, Vinolo MAR, Boucher J, Mori MA (2020) Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression. Sci Adv 6:eabc6250. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
Ost 2020 EMBO Rep | 2020 | Ost M, Igual Gil C, Coleman V, Keipert S, Efstathiou S, Vidic V, Weyers M, Klaus S (2020) Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Pola 2020 Invest New Drugs | 2020 | Pola M, Kolarova H, Ruzicka J, Zholobenko A, Modriansky M, Mosinger J, Bajgar R (2020) Effects of zinc porphyrin and zinc phthalocyanine derivatives in photodynamic anticancer therapy under different partial pressures of oxygen in vitro. Invest New Drugs 39:89-97. | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
Cecatto 2020 Toxicol In Vitro | 2020 | Cecatto C, Amaral AU, Roginski AC, Castilho RF, Wajner M (2020) Impairment of mitochondrial bioenergetics and permeability transition induction caused by major long-chain fatty acids accumulating in VLCAD deficiency in skeletal muscle as potential pathomechanisms of myopathy. Toxicol In Vitro 62:104665. | LEAK OXPHOS ET | N S | Permeabilized tissue Isolated mitochondria | Rat | Skeletal muscle |
Jayakumari 2020 J Diabetes | 2020 | Jayakumari NR, Rajendran RS, Sivasailam A, Vimala SS, Nanda S, Manjunatha S, Pillai VV, Karunakaran J, Gopala S (2020) Impaired substrate-mediated cardiac mitochondrial complex I respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic Asian Indians. J Diabetes 12:542-55. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Human | Heart |
Truong 2020 Cytokine | 2020 | Truong NTT, Lydic TA, Bazil JN, Suryadevara A, Olson LK (2020) Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: a link to anti-viral function. Cytokine 133:155147. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Gumpp 2020 Proc Natl Acad Sci U S A | 2020 | Gumpp AM, Boeck C, Behnke A, Bach AM, Ramo-Fernández L, Welz T, Gündel H, Kolassa IT, Karabatsiakis A (2020) Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells. Proc Natl Acad Sci U S A 117:24778-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Oellermann 2020 Sci Rep | 2020 | Oellermann M, Hickey AJR, Fitzgibbon QP, Smith G (2020) Thermal sensitivity links to cellular cardiac decline in three spiny lobsters. Sci Rep 10:202. | LEAK OXPHOS ET | N S NS | Homogenate | Crustaceans | Heart |
Burtscher 2020 eNeuro | 2020 | Burtscher J, Copin JC, Sandi C, Lashuel HA (2020) Pronounced α-synuclein pathology in a seeding-based mouse model is not sufficient to induce mitochondrial respiration deficits in the striatum and amygdala. eNeuro 7:ENEURO.0110-20.2020. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Hayes 2020 Nutrients | 2020 | Hayes P, Fergus C, Ghanim M, Cirzi C, Burtnyak L, McGrenaghan CJ, Tuorto F, Nolan DP, Kelly VP (2020) Queuine micronutrient deficiency promotes Warburg metabolism and reversal of the mitochondrial ATP synthase in HeLa cells. Nutrients 12:E871. | LEAK ROUTINE OXPHOS ET | N S Gp CIV ROX | Permeabilized cells Intact cells | Human | HeLa |
Gutierrez 2020 Sci Signal | 2020 | Gutiérrez T, Qi H, Yap MC, Tahbaz N, Milburn LA, Lucchinetti E, Lou PH, Zaugg M, LaPointe PG, Mercier P, Overduin M, Bischof H, Burgstaller S, Malli R, Ballanyi K, Shuai J, Simmen T (2020) The ER chaperone calnexin controls mitochondrial positioning and respiration . Sci Signal 13:eaax6660. | LEAK ROUTINE ET | Intact cells | Mouse | Fibroblast | |
Hedges 2020 Biosci Rep | 2020 | Hedges CP, Pham T, Shetty B, Masson SWC, Hickey AJR, Shepherd PR, Merry TL (2020) Prolonged treatment with a PI3K p110α inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function. https://doi.org/10.1042/bsr20201128 | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Liver |
Tepp 2020 Biochim Biophys Acta Gen Subj | 2020 | Tepp K, Puurand M, Timohhina N, Aid-Vanakova J, Reile I, Shevchuk I, Chekulayev V, Eimre M, Peet N, Kadaja L, Paju K, Kaambre T (2020) Adaptation of striated muscles to Wolframin deficiency in mice: Alterations in cellular bioenergetics. Biochim Biophys Acta Gen Subj 1864:129523. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Mouse | Heart Skeletal muscle |
Kupats 2020 Oxid Med Cell Longev | 2020 | Kupats E, Stelfa G, Zvejniece B, Grinberga S, Vavers E, Makrecka-Kuka M, Svalbe B, Zvejniece L, Dambrova M (2020) Mitochondrial-protective effects of R-phenibut after experimental traumatic brain injury. Oxid Med Cell Longev 2020:9364598. | LEAK OXPHOS ET | N S NS | Homogenate Isolated mitochondria | Mouse | Nervous system |
Reutzel 2020 Oxid Med Cell Longev | 2020 | Reutzel M, Grewal R, Dilberger B, Silaidos C, Joppe A, Eckert GP (2020) Cerebral mitochondrial function and cognitive performance during aging: A longitudinal study in NMRI mice. Oxid Med Cell Longev 2020:4060769. | LEAK ET OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Wu 2020 Chemosphere | 2020 | Wu F, Sokolov EP, Dellwig O, Sokolova IM (2020) Season-dependent effects of ZnO nanoparticles and elevated temperature on bioenergetics of the blue mussel Mytilus edulis. Chemosphere 263:127780. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Molluscs | Other cell lines |
Zavadskis 2020 Pharmaceutics | 2020 | Zavadskis S, Weidinger A, Hanetseder D, Banerjee A, Schneider C, Wolbank S, Marolt Presen D, Kozlov AV (2020) Effect of diphenyleneiodonium chloride on intracellular reactive oxygen species metabolism with emphasis on NADPH oxidase and mitochondria in two therapeutically relevant human cell types. Pharmaceutics 13:E10. | LEAK OXPHOS ET | N S | Permeabilized cells | Human | Other cell lines |
Makrecka-Kuka 2020 Cardiovasc Drugs Ther | 2020 | Makrecka-Kuka Marina, Korzh Stanislava, Videja Melita, Vilks Karlis, Cirule Helena, Kuka Janis, Dambrova Maija, Liepinsh Edgars (2020) Empagliflozin protects cardiac mitochondrial fatty acid metabolism in a mouse model of diet-induced lipid overload. Cardiovasc Drugs Ther 34:791-97. | OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Heart |
Owiredu 2020 Toxicol Rep | 2020 | Owiredu S, Ranganathan A, Greenwood JC, Piel S, Janowska JI, Eckmann DM, Kelly M, Ehinger JK, Kilbaugh TJ, Jang DH (2020) In vitro comparison of hydroxocobalamin (B12a) and the mitochondrial directed therapy by a succinate prodrug in a cellular model of cyanide poisoning. Toxicol Rep 7:1263-71. | ROUTINE ET | CIV ROX | Intact cells | Human | Blood cells Other cell lines |
Mahul-Mellier 2020 Proc Natl Acad Sci U S A | 2020 | Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Nervous system |
Eshima 2020 J Appl Physiol (1985) | 2020 | Eshima H, Siripoksup P, Mahmassani ZS, Johnson JM, Ferrara PJ, Verkerke ARP, Salcedo A, Drummond MJ, Funai K (2020) Neutralizing mitochondrial ROS does not rescue muscle atrophy induced by hindlimb unloading in female mice. J Appl Physiol (1985) 129:124-32. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Skeletal muscle |
Garcia 2020 Mol Hum Reprod | 2020 | Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52. | LEAK OXPHOS ET | S | Isolated mitochondria | Mouse | Liver |
Piel 2020 PLoS One | 2020 | Piel S, Chamkha I, Dehlin AK, Ehinger JK, Sjövall F, Elmér E, Hansson MJ (2020) Cell-permeable succinate prodrugs rescue mitochondrial respiration in cellular models of acute acetaminophen overdose. PLoS One 15:e0231173. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Liver Platelet |
Mayoral-Varo 2020 PLoS One | 2020 | Mayoral-Varo V, Calcabrini A, Sánchez-Bailón MP, Martínez-Costa ÓH, González-Páramos C, Ciordia S, Hardisson D, Aragón JJ, Fernández-Moreno MÁ, Martín-Pérez J (2020) c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells . PLoS One 15:e0235850. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Woessner 2020 Thesis | 2020 | Woessner MN (2020) BEET-HF: The effects of dietary inorganic nitrate supplementation on aerobic exercise performance, vascular function, cardiac performance and mitochondrial respiration in patients with heart failure with reduced ejection fraction. PhD Thesis 198. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Cecatto 2020 Mitochondrion | 2020 | Cecatto C, Amaral AU, Wajner A, Wajner SM, Castilho RF, Wajner M (2020) Disturbance of mitochondrial functions associated with permeability transition pore opening induced by cis-5-tetradecenoic and myristic acids in liver of adolescent rats. Mitochondrion 50:1-13. | LEAK OXPHOS ET | N S | Permeabilized cells Isolated mitochondria | Rat | Liver Other cell lines |
Kahancova 2020 Sci Rep | 2020 | Kahancová A, Sklenář F, Ježek P, Dlasková A (2020) Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells. Sci Rep 10:1551. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Hassan 2020 MitoFit Preprint Arch | 2020 | Hassan Hazirah, Gnaiger Erich, Zakaria Fazaine, Makpol Suzana, Abdul Karim Norwahidah (2020) Alterations in mitochondrial respiratory capacity and membrane potential: a link between mitochondrial dysregulation and autism. https://doi.org/10.26124/mitofit:200003 | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | |
Larsen 2020 Cardiovasc Drugs Ther | 2020 | Larsen AH, Wiggers H, Dollerup OL, Jespersen NR, Hansson NH, Frøkiær J, Brøsen K, Nørrelund H, Bøtker HE, Møller N, Jessen N (2020) Metformin lowers body weight but fails to increase insulin sensitivity in chronic heart failure patients without diabetes: a randomized, double-blind, placebo-controlled study. Cardiovasc Drugs Ther 35:491-503. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Plecita-Hlavata 2020 Antioxid Redox Signal | 2020 | Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD+ ratio. Antioxid Redox Signal 33:789-815. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus |
Dawson 2020 Exp Gerontol | 2020 | Dawson NJ, Salmón P (2020) Age-related increase in mitochondrial quantity may mitigate a decline in mitochondrial quality in red blood cells from zebra finches (Taeniopygia guttata). Exp Gerontol 133:110883. | LEAK ROUTINE ET | ROX | Intact cells | Birds | Blood cells |
Ayari 2020 Commun Biol | 2020 | Ayari Asma, Rosa-Calatrava Manuel, Lancel Steve, Barthelemy Johanna, Pizzorno Andres, Mayeuf-Louchart Alicia, Baron Morgane, Hot David, Deruyter Lucie, Soulard Daphnee, Julien Thomas, Faveeuw Christelle, Molendi-Coste Olivier, Dombrowicz David, Sedano Laura, Sencio Valentin, Le Goffic Ronan, Trottein Francois, Wolowczuk Isabelle (2020) Influenza infection rewires energy metabolism and induces browning features in adipose cells and tissues. Commun Biol 3:237. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Fat |
Mikulas 2020 Materials | 2020 | Mikulás K, Komlódi T, Földes A, Sváb G, Horváth G, Nagy AM, Ambrus A, Gyulai-Gaál Sz, Gera I, Hermann P, Varga G, Tretter L (2020) Bioenergetic Impairment of triethylene glycol dimethacrylate- (TEGDMA-) treated dental pulp stem cells (DPSCs) and isolated brain mitochondria are amended by redox compound methylene blue. Materials (Basel) 13(16):3472. | OXPHOS ET ROUTINE | N S ROX | Isolated mitochondria Permeabilized cells Intact cells | Guinea pig Human | Stem cells |
Locatelli 2020 FASEB J | 2020 | Locatelli L, Cazzaniga A, De Palma C, Castiglioni S, Maier JAM (2020) Mitophagy contributes to endothelial adaptation to simulated microgravity. FASEB J 34:1833-45. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Roy Chowdhury 2020 Cancers (Basel) | 2020 | Roy Chowdhury S, Bouchard EDJ, Saleh R, Nugent Z, Peltier C, Mejia E, Hou S, McFall C, Squires M, Hewitt D, Davidson L, Shen GX, Johnston JB, Doucette C, Hatch GM, Fernyhough P, Marshall A, Gibson SB, Dawe DE, Banerji V (2020) Mitochondrial respiration correlates with prognostic markers in chronic lymphocytic leukemia and is normalized by ibrutinib treatment. Cancers (Basel) 12:E650. | LEAK ET ROUTINE | ROX | Intact cells | Human | Lymphocyte Blood cells |
Falcao-Tebas 2020 J Physiol | 2020 | Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK (2020) Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol 598:4251-70. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
He 2020 Clin Transl Med | 2020 | He C, Gao P, Cui Y, Li Q, Li Y, Lu Z, Ma H, Zhao Y, Li L, Sun F, Chen, X, Jia H, Liu D, Yang G, Zheng H, Zhu Z (2020) Low‐glucose‐sensitive TRPC6 dysfunction drives hypoglycemia‐induced cognitive impairment in diabetes. Clin Transl Med 10:e205. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Nervous system |
Baxter 2020 Elife | 2020 | Baxter M, Voronkov M, Poolman T, Galli G, Pinali C, Goosey L, Knight A, Krakowiak K, Maidstone R, Iqbal M, Zi M, Prehar S, Cartwright EJ, Gibbs J, Matthews LC, Adamson AD, Humphreys NE, Rebelo-Guiomar P, Minczuk M, Bechtold DA, Loudon A, Ray D (2020) Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife 9:e50705. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Heart |
Kanellopoulos 2020 Cell | 2020 | Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Drosophila | Nervous system Other cell lines |
Leguina-Ruzzi 2020 Biomolecules | 2020 | Leguina-Ruzzi A, Vodičková A, Holendová B, Pavluch V, Tauber J, Engstová H, Dlasková A, Ježek P (2020) Glucose-induced expression of DAPIT in pancreatic β-cells. Biomolecules 10:E1026. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Pelaez Coyotl 2020 Pharmaceutics | 2020 | Peláez Coyotl EA, Barrios Palacios J, Muciño G, Moreno-Blas D, Costas M, Montiel Montes T, Diener C, Uribe-Carvajal S, Massieu L, Castro-Obregón S, Espinosa OR, Mata Espinosa D, Barrios-Payan J, León Contreras JC, Corzo G, Hernández-Pando R, Del Rio G (2020) Antimicrobial peptide against Mycobacterium tuberculosis that activates autophagy is an effective treatment for tuberculosis. Pharmaceutics 12:E1071. | ROUTINE ET | Intact cells | Mouse | Fibroblast | |
Fuller 2020 J Appl Physiol (1985) | 2020 | Fuller KNZ, McCoin CS, Allen J, Bell-Glenn S, Koestler DC, Dorn Ii GW, Thyfault JP (2020) Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice. J Appl Physiol (1985) 128:1251-61. | LEAK OXPHOS ET | F N NS | Isolated mitochondria | Mouse | Liver |
Lin 2020 Preprints | 2020 | Lin M, Fu T, Hsu C, Huang S, Lin Y, Wang J (2020) Cycling exercise training enhances mitochondrial bioenergetics of platelets in patients with peripheral arterial disease: a randomized controlled trial. Preprints 2020070567. | LEAK ROUTINE OXPHOS ET | F N S Gp NS ROX | Permeabilized cells Intact cells | Human | Platelet |
Dia 2020 Basic Res Cardiol | 2020 | Dia M, Gomez L, Thibault H, Tessier N, Leon C, Chouabe C, Ducreux S, Gallo-Bona N, Tubbs E, Bendridi N, Chanon S, Leray A, Belmudes L, Couté Y, Kurdi M, Ovize M, Rieusset J, Paillard M (2020) Reduced reticulum-mitochondria Caysup>2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy. Basic Res Cardiol 115:74. | ROUTINE ET | Intact cells | Mouse | Heart | |
Janowska 2020 Toxicol In Vitro | 2020 | Janowska JI, Piel S, Saliba N, Kim CD, Jang DH, Karlsson M, Kilbaugh TJ, Ehinger JK (2020) Mitochondrial respiratory chain Complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug carbamate toxicity and treatment. Toxicol In Vitro 65:104794. | LEAK ROUTINE ET | N S NS ROX | Permeabilized cells Intact cells | Human | Platelet Blood cells |
Allen 2020 Thesis | 2020 | Allen FM (2020) Mitochondrial metabolism elucidated by rapid fractionation from tissue. PhD Thesis 298. | LEAK ET | S | Isolated mitochondria | Mouse Rat | Heart Liver |
Alston 2020 Am J Hum Genet | 2020 | Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW (2020) Pathogenic bi-allelic mutations in NDUFAF8 cause Leigh syndrome with an isolated complex I deficiency. Am J Hum Genet 106:92-101. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Fibroblast |
Xia 2020 Biomed Res Int | 2020 | Xia W, Wang Q, Lu Y, Hu Y, Zhang X, Zhang J, Liu D, Song J, Zhu Z, Liu D, Zhang H (2020) Transient receptor potential channel canonical type 3 deficiency antagonizes myofibroblast transdifferentiation in vivo. Biomed Res Int 2020:1202189. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Luevano-Martinez 2020 FEBS Lett | 2020 | Luévano-Martínez LA, Girard RMBM, Alencar MB, Silber AM (2020) ATP regulates the activity of an alternative oxidase in Trypanosoma brucei. FEBS Lett [Epub ahead of print]. | LEAK ROUTINE ET | Intact cells | Protists | ||
Avila-Rojas 2020 Food Chem Toxicol | 2020 | Avila-Rojas SH, Aparicio-Trejo OE, Briones-Herrera A, Medina-Campos ON, Reyes-Fermín LM, Martínez-Klimova E, León-Contreras JC, Hernández-Pando R, Tapia E, Pedraza-Chaverri J (2020) Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin. Food Chem Toxicol 145:111774. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Kidney |
Protasoni 2020 EMBO J | 2020 | Protasoni M, Pérez-Pérez R, Lobo-Jarne T, Harbour ME, Ding S, Peñas A, Diaz F, Moraes CT, Fearnley IM, Zeviani M, Ugalde C, Fernández-Vizarra E (2020) Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IV. EMBO J 39:e102817. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
Maeda 2020 J Cell Mol Med | 2020 | Maeda H, Kami D, Maeda R, Murata Y, Jo JI, Kitani T, Tabata Y, Matoba S, Gojo S (2020) TAT-dextran-mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes. J Cell Mol Med 24:5007-20. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria Intact cells | Rat | Heart |
Oliveira 2020 Anim Reprod | 2020 | Oliveira VS, Castro AJG, Domingues JT, Souza AZP, Scheffer DL, Latini A, Soares CHL, Van Der Kraak G, Silva FRMB (2020) A brazilian pulp and paper mill effluent disrupts energy metabolism in immature rat testis and alters sertoli cell secretion and mitochondrial activity. Anim Reprod 17:e20190116. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Genital |
Caspi 2020 J Am Heart Assoc | 2020 | Caspi T, Straw S, Cheng C, Garnham JO, Scragg JL, Smith J, Koshy AO, Levelt E, Sukumar P, Gierula J, Beech DJ, Kearney MT, Cubbon RM, Wheatcroft SB, Witte KK, Roberts LD, Bowen TS (2020) Unique transcriptome signature distinguishes patients with heart failure with myopathy. J Am Heart Assoc 9:e017091. https://doi.org/10.1161/JAHA.120.017091 | LEAK OXPHOS ET | N S CIV NS | Permeabilized tissue | Human | Heart Skeletal muscle |
Carvalho-Kelly 2020 J Bioenerg Biomembr | 2020 | Carvalho-Kelly LF, Pralon CF, Rocco-Machado N, Nascimento MT, Carvalho-de-Araujo AD, Meyer-Fernandes JR (2020) Acanthamoeba castellanii phosphate transporter (AcPHS) is important to maintain inorganic phosphate influx and is related to trophozoite metabolic processes. J Bioenerg Biomembr 52:93-102. | ET | Intact cells | Protists | ||
Allen 2020 Commun Biol | 2020 | Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR (2020) The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol 3:389. | LEAK OXPHOS ET | N S CIV | Permeabilized tissue | Rat | Heart |
Battaglia 2020 Cell Death Dis | 2020 | Battaglia CR, Cursano S, Calzia E, Catanese A, Boeckers TM (2020) Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons. Cell Death Dis 11:1004. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells | Rat | Nervous system |
Peres de Oliveira 2020 Proteome Sci | 2020 | Peres de Oliveira A, Basei FL, Slepicka PF, de Castro Ferezin C, Melo-Hanchuk TD, de Souza EE, Lima TI, Dos Santos VT, Mendes D, Silveira LR, Menck CFM, Kobarg J (2020) NEK10 interactome and depletion reveal new roles in mitochondria. Proteome Sci 18:4. | LEAK ROUTINE ET | Intact cells | Human | HeLa | |
Hoffmann 2020 J Clin Endocrinol Metab | 2020 | Hoffmann C, Schneeweiss P, Randrianarisoa E, Schnauder G, Kappler L, Machann J, Schick F, Fritsche A, Heni M, Birkenfeld A, Niess AM, Häring HU, Weigert C, Moller A (2020) Response of mitochondrial respiration in adipose tissue and muscle to 8 weeks of endurance exercise in obese subjects. J Clin Endocrinol Metab 105:dgaa571. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle Fat |
Boehmert 2020 Transfusion | 2020 | Böhmert S, Kübel S, Müller MM, Weber CF, Adam EH, Dröse S, Zacharowski K, Fischer D (2020) The effect of the interruption of agitation, temporary cooling, and pneumatic tube transportation on platelet quality during storage for transfusion. Transfusion 61:1258-65. | LEAK ROUTINE ET | CIV | Intact cells | Human | Platelet |
MitoEAGLE muscle 1 | 2020 | Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08 | LEAK OXPHOS ET | N NS S ROX | Permeabilized tissue | Human | Skeletal muscle |
Lensu 2020 Preprints | 2020 | Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Linden J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides targeting Faecalibacterium prausnitzii prevent high fat diet-induced hepatic steatosis in rats. Preprints 2020:2020090241. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Burtscher 2020 Int J Mol Sci | 2020 | Burtscher J, Di Pardo A, Maglione V, Schwarzer C, Squitieri F (2020) Mitochondrial respiration changes in R6/2 Huntington's Disease model mice during aging in a brain region specific manner. Int J Mol Sci 21:5412. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Irion 2020 Stem Cells Int | 2020 | Irion CI, Martins EL, Christie MLA, de Andrade CBV, de Moraes ACN, Ferreira RP, Pimentel CF, Suhett GD, Campos de Carvalho AC, Lindoso RS, Vieyra A, Galina A, Goldenberg RCS (2020) Acute myocardial infarction reduces respiration in rat cardiac fibers, despite adipose tissue mesenchymal stromal cell transplant. Stem Cells Int 2020:4327965 . | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Heart |
Weger 2020 Sci Rep | 2020 | Weger M, Alpern D, Cherix A, Ghosal S, Grosse J, Russeil J, Gruetter R, de Kloet ER, Deplancke B, Sandi C (2020) Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress. Sci Rep 10:18308. | OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Juarez-Flores 2020 Antioxidants (Basel) | 2020 | Juarez-Flores DL, Ezquerra M, Gonzalez-Casacuberta I, Ormazabal A, Moren C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Munoz E, Tobias E, Compta Y, Garcia-Garcia FJ, Garcia-Ruiz C, Fernandez-Checa JC, Marti MJ, Grau JM, Cardellach F, Artuch R, Fernandez-Santiago R, Garrabou G (2020) Disrupted mitochondrial and metabolic plasticity underlie comorbidity between age-related and degenerative disorders as Parkinson disease and type 2 diabetes mellitus. Antioxidants (Basel) 9:1063. | LEAK ROUTINE ET | ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Evinova 2020 J Membr Biol | 2020 | Evinova A, Cizmarova B, Hatokova Z, Racay P (2020) High‑resolution respirometry in assessment of mitochondrial function in neuroblastoma SH‑SY5Y intact cells. J Membr Biol 253:129-36. | LEAK ROUTINE ET | N S ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
Song 2020 Life Sci | 2020 | Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633. | LEAK OXPHOS ET | F N NS | Homogenate | Mouse | Liver |
Madeo 2020 US Patent | 2020 | Madeo F, Eisenberg T, Stekovic S (2020) Use of spermidine for the enhancement of mitochondrial respiration. US Patent US20200054579 A1. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Heart |
Hijazi 2020 J Cell Sci | 2020 | Hijazi I, Knupp J, Chang A (2020) Retrograde signaling mediates an adaptive survival response to endoplasmic reticulum stress. J Cell Sci 133:jcs241539. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Pajuelo-Reguera 2020 Cells | 2020 | Pajuelo Reguera David, Čunátová Kristýna, Vrbacký Marek, Pecinová Alena, Houštěk Josef, Mráček Tomáš, Pecina Petr (2020) Cytochrome c oxidase subunit 4 isoform exchange results in modulation of oxygen affinity. Cells 9:E443. | OXPHOS ET | N S Gp NS Other combinations | Permeabilized cells Oxidase;biochemical oxidation | Human | HEK |
BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 | LEAK OXPHOS ET | F N S Gp DQ CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | ||
Musi 2020 Aging Cell | 2020 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2020) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
MitoEAGLE blood cells 1 | 2020 | Åsander Frostner Eleonor*, Aburel Oana M*, Avram Vlad F*, Calabria Elisa, Castelo Rueda Maria Paulina*, Chamkha Imen*, Čižmárová Beata, Danila Maria-Daniela*, Doerrier Carolina*, Eckert Gunter P*, Ehinger Johannes K, Elmer Eskil*, Garcia-Souza Luiz F*, Gnaiger Erich*, Hoppel Florian*, Karabatsiakis Alexander*, Keppner Gloria, Kidere Dita*, Krako Jakovljević Nina, Labieniec-Watala Magdalena*, Lelcu Theia*, Micankova Petra, Michalak Slawomir*, Molina Anthony JA*, Pavlovic Kasja, Pichler Irene*, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina*, Silaidos Carmina*, Sjövall Fredrik*, Sobotka Ondrej*, Sumbalova Zuzana*, Swiniuch Daria, Vernerova Andrea*, Volani Chiara*, Vujacic-Mirski Ksenija*, Watala Cezary* (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Intact cells Permeabilized cells | Human | Blood cells Platelet |
Hraoui 2020 J Exp Biol | 2020 | Hraoui G, Bettinazzi S, Gendron AD, Boisclair D, Breton S (2020) Mitochondrial thermo-sensitivity in invasive and native freshwater mussels. J Exp Biol 223:jeb215921. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Molluscs | Lung;gill |
Gruenig 2020 Biochem Pharmacol | 2020 | Grünig D, Szabo L, Marbet M, Krähenbühl S (2020) Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms. Biochem Pharmacol 177:113860. | LEAK OXPHOS ET | N S DQ CIV ROX | Isolated mitochondria | Mouse | Liver |
Vega 2020 Physiol Rep | 2020 | Vega RB, Brouwers B, Parsons SA, Stephens NA, Pino MF, Hodges A, Yi F, Yu G, Pratley RE, Smith SR, Sparks LM (2020) An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression. Physiol Rep 8:e14416. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Lensu 2020 Nutrients | 2020 | Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Lindén J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides ameliorate high-fat-diet-induced hepatic steatosis in rats . Nutrients 12:E3225. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Kline 2020 Nitric Oxide | 2020 | Kline JA, Puskarich MA, Pike JW, Zagorski J, Alves NJ (2020) Inhaled nitric oxide to control platelet hyper-reactivity in patients with acute submassive pulmonary embolism. Nitric Oxide 96:20-8. | LEAK ET | ROX | Intact cells | Human | Platelet Blood cells |
Woessner 2020 J Appl Physiol (1985) | 2020 | Woessner MN, Neil C, Saner NJ, Goodman CA, McIlvenna LC, Ortiz de Zevallos J, Garnham AP, Levinger I, Allen JD (2020) Effect of inorganic nitrate on exercise capacity, mitochondria respiration and vascular function in heart failure reduced ejection fraction. J Appl Physiol (1985) 128:1355-64. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Maddison 2020 PLoS Genet | 2020 | Maddison DC, Alfonso-Núñez M, Swaih AM, Breda C, Campesan S, Allcock N, Straatman-Iwanowska A, Kyriacou CP, Giorgini F (2020) A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics. PLoS Genet 16:e1009129. | OXPHOS ET | N S NS | Homogenate | Drosophila | |
Ulgherait 2020 Nat Commun | 2020 | Ulgherait Matt, Chen Anna, McAllister Sophie F, Kim Han X, Delventhal Rebecca, Wayne Charlotte R, Garcia Christian J, Recinos Yocelyn, Oliva Miles, Canman Julie C, Picard Martin, Owusu-Ansah Edward, Shirasu-Hiza Mimi (2020) Circadian regulation of mitochondrial uncoupling and lifespan. Nat Commun 11:1927. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Drosophila | |
Zhang 2020 Acta Pharmacol Sin | 2020 | Zhang L, Wang YN, Ju JM, Shabanova A, Li Y, Fang RN, Sun JB, Guo YY, Jin TZ, Liu YY, Li TY, Shan HL, Liang HH, Yang BF (2020) Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation. Acta Pharmacol Sin 42:691-700. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Heart |
Reddoch-Cardenas 2020 Transfusion | 2020 | Reddoch-Cardenas KM, Peltier GC, Chance TC, Nair PM, Meledeo MA, Ramasubramanian AK, Cap AP, Bynum JA (2020) Cold storage of platelets in platelet additive solution maintains mitochondrial integrity by limiting initiation of apoptosis-mediated pathways. Transfusion 61:178-90. | ROUTINE ET | Intact cells | Human | Platelet | |
Romeiro 2020 bioRxiv | 2020 | Romeiro NC, Ferreira CM, Oliveira MF (2020) Assessment of mitochondrial physiology of murine white adipose tissue by mechanical permeabilization and lipid depletion. bioRxiv doi: https://doi.org/10.1101/2020.02.19.956870. | LEAK OXPHOS ET | S ROX | Permeabilized tissue | Mouse | Fat |
Coppin 2020 Cell Death Dis | 2020 | Coppin L, Jannin A, Ait Yahya E, Thuillier C, Villenet C, Tardivel M, Bongiovanni A, Gaston C, de Beco S, Barois N, van Seuningen I, Durand E, Bonnefond A, Vienne JC, Vamecq J, Figeac M, Vincent A, Delacour D, Porchet N, Pigny P (2020) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface. Cell Death Dis 11:360. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells Intact cells | Human | Islet cell;pancreas;thymus Endothelial;epithelial;mesothelial cell |
Assis-de-Lemos 2020 Curr Protoc Toxicol | 2020 | Assis-de-Lemos G, Ledur PF, Karmirian K, Rehen SK, Galina A (2020) A protocol to study mitochondrial function in human neural progenitors and iPSC-derived astrocytes. Curr Protoc Toxicol 85:e97. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Smolkova 2020 Sci Rep | 2020 | Smolková K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubálek M, Holendová B, Vítek L, Ježek P (2020) SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2 . Sci Rep 10:8677. | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines | |
Zulkifli 2020 Nat Commun | 2020 | Zulkifli M, Neff JK, Timbalia SA, Garza NM, Chen Y, Watrous JD, Murgia M, Trivedi PP, Anderson SK, Tomar D, Nilsson R, Madesh M, Jain M, Gohil VM (2020) Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism. Nat Commun 11:4866. | ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Cubizolle 2020 J Cell Mol Med | 2020 | Cubizolle A, Cia D, Moine E, Jacquemot N, Guillou L, Rosell M, Angebault-Prouteau C, Lenaers G, Meunier I, Vercauteren J, Durand T, Crauste C, Brabet P (2020) Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal. J Cell Mol Med 24:5057-69. | LEAK OXPHOS ET | N S CIV NS | Permeabilized cells | Rat | Endothelial;epithelial;mesothelial cell |
Edmunds 2020 Mol Metab | 2020 | Edmunds LR, Xie B, Mills AM, Huckestein BR, Undamatla R, Murali A, Pangburn MM, Martin J, Sipula I, Kaufman BA, Scott I, Jurczak MJ (2020) Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance. Mol Metab 41:101051. | LEAK OXPHOS ET | F N ROX | Homogenate | Mouse | Liver |
E-L coupling efficiency | 2020 | Gnaiger E (2020) Biochemical coupling efficiency: from 0 to <1. Mitochondr Physiol Network (2015-01-18) last update 2020-11-12. | LEAK ET | ||||
Brum 2020 Mol Neurobiol | 2020 | Brum EDS, Fialho MFP, Fischer SPM, Hartmann DD, Gonçalves DF, Scussel R, Machado-de-Ávila RA, Dalla Corte CL, Soares FAA, Oliveira SM (2020) Relevance of mitochondrial dysfunction in the reserpine-induced experimental fibromyalgia model. Mol Neurobiol 57:4202-17. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Nervous system |
Rodriguez 2020 J Gerontol A Biol Sci Med Sci | 2020 | Rodríguez E, Hakkou M, Hagen TM, Lemieux H, Blier PU (2020) Divergences in the control of mitochondrial respiration are associated with lifespan variation in marine bivalves. J Gerontol A Biol Sci Med Sci 76:796-804. | LEAK OXPHOS ET | F N S Gp CIV ROX | Isolated mitochondria | Molluscs | |
Pena 2020 Int J Chronic Dis | 2020 | Pena GS, Paez HG, Johnson TK, Halle JL, Carzoli JP, Visavadiya NP, Zourdos MC, Whitehurst MA, Khamoui AV (2020) Hippocampal growth factor and myokine cathepsin B expression following aerobic and resistance training in 3xTg-AD mice. Int J Chronic Dis 2020:Article ID 5919501. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Jian 2020 Cell Metab | 2020 | Jian C, Fu J, Cheng X, Shen LJ, Ji YX, Wang X, Pan S, Tian H, Tian S, Liao R, Song K, Wang HP, Zhang X, Wang Y, Huang Z, She ZG, Zhang XJ, Zhu L, Li H (2020) Low-dose sorafenib acts as a mitochondrial uncoupler and ameliorates nonalcoholic steatohepatitis. Cell Metab 31:892-908. https://doi.org/10.1016/j.cmet.2020.04.011 | LEAK OXPHOS ET | N S CIV ROX | Permeabilized cells | Mouse | Liver |
Chang 2020 J Biol Chem | 2020 | Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Brand 2020 J Clin Med | 2020 | Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout-an interventional pilot study. J Clin Med 9:E667. | LEAK OXPHOS ET | N CIV ROX | Permeabilized cells | Human | Lymphocyte |
Fecker 2020 Biomolecules | 2020 | Fecker R, Buda V, Alexa E, Avram S, Pavel IZ, Muntean D, Cocan I, Watz C, Minda D, Dehelean CA, Soica C, Danciu C (2020) Phytochemical and biological screening of Oenothera biennis L. hydroalcoholic extract. Biomolecules 10:E818. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |