Talk:FAT4BRAIN School IOC147 Virtual Event

• 2020-10-13 Tu

• 13:00 CEST, 14:00 EEST Maija Dambrova (Latvian Institute of Organic Synthesis, Riga, LV) Welcome and introduction to the FAT4BRAIN project

• 13:10 CEST, 14:10 EEST Erich Gnaiger (Oroboros, Innsbruck, AT) Mitochondrial respiratory control - Coupling-control

• 13:50 CEST, 14:50 EEST Erich Gnaiger (Oroboros, Innsbruck, AT) Mitochondrial respiratory control - Pathway control

• 14:30 CEST, 15:30 EEST Marina Makrecka-Kuka (Latvian Institute of Organic Synthesis, Riga, LV) "Substrates for measuring fatty acid oxidation: which the best?"

• 14:50 CEST, 15:50 EEST Carolina Doerrier (Oroboros, Innsbruck, AT) Sample types and mitochondrial preparations

• 15:10 CEST, 16:10 EEST Q&A - general discussion with lecturers, Luiza Cardoso and Cristiane Cecatto

• 15:40 CEST, 16:40 EEST Coffee break

• 16:00 CEST, 17:00 EEST Zümrüt Duygu Sen, INSTITUTION, TITLE

• 16:20 CEST, 17:20 EEST Q&A - discussion

• 16:30 CEST, 17:30 EEST Invited guest lecture: Johannes Burtscher (The Institute of Sport Sciences of the University of Lausanne, CH) "Fatal attraction – when alpha-synuclein gets intimate with mitochondria"

• 17:00 CEST, 18:00 EEST Q&A - discussion

• 17:15 CEST, 18:15 EEST Final discussion - next steps

Tentative programme IOC147 - Virtual version

in preparation 

Video-lectures - to be watched prior to the discussion sessions:

• Video-lecture by Erich Gnaiger (Oroboros, Innsbruck, AT) Introduction 1: Mitochondrial respiratory control - Coupling-control ratio

• Video-lecture by Erich Gnaiger (Oroboros, Innsbruck, AT) Introduction 2: Mitochondrial respiratory control - pathway control

• Video-lecture by Carolina Doerrier (Oroboros, Innsbruck, AT) Introduction 3: Sample types and mitochondrial preparations

• 2020-10-13 Tu

Discussion sessions:

• 13:00 CEST, 14:00 EEST Maija Dambrova (Latvian Institute of Organic Synthesis, Riga, LV) Welcome and introduction to the FAT4BRAIN project

• 13:10 CEST, 14:10 EEST Marina Makrecka-Kuka (Latvian Institute of Organic Synthesis, Riga, LV) "Substrates for measuring fatty acid oxidation: which the best?"

• 13:30 CEST, 14:30 EEST Q&A - general discussion with Luiza Cardoso, Cristiane Cecatto and Marina Makrecka-Kuka

• 15:00 CEST, 16:00 EEST Coffee break

• 15:45 CEST, 16:45 EEST To be confirmed: Invited guest lecture

• 16:15 CEST, 17:15 EEST Q&A - discussion

• 16:30 CEST, 17:30 EEST Invited guest lecture: Johannes Burtscher (The Institute of Sport Sciences of the University of Lausanne, CH) "Fatal attraction – when alpha-synuclein gets intimate with mitochondria"

• 17:00 CEST, 18:00 EEST Q&A - discussion

• 17:15 CEST, 18:15 EEST Final discussion - next steps

Former programme IOC147

• 2020-10-12 Mo

• 09:00 Maija Dambrova (Latvian Institute of Organic Synthesis, Riga, Latvia) Welcome and introduction to the FAT4BRAIN project
• 09:30 Erich Gnaiger (Oroboros, Innsbruck, AT) Introduction 1: Mitochondrial respiratory control - Coupling-control ratio

11:00 Coffee/tea break

• 11:30 Erich Gnaiger (Oroboros, Innsbruck, AT) Introduction 2: Mitochondrial respiratory control - pathway control

13:00 Lunch

• 14:30 Erich Gnaiger (Oroboros, Innsbruck, AT) Introduction 3: High-resolution respirometry and applications to brain mitochondrial function

16:00 Coffee/tea break

• 16:30 Short presentations by participants (S1-S4)
• 17:30 Q&A - general discussion

• 2020-10-13 Tu

• 09:00 Alexander Karabatsiakis (University of Innsbruck, AT) Invited guest lecture: Biochemical fingerprinting in blood serum of individuals exposed to early childhood trauma reveals changes in fatty acid metabolism associated with alterations in neuronal turnover and membrane degradation
• 10:00 Luiza Cardoso (Oroboros, Innsbruck, AT) O2k demo experiment: QC in high-resolution respirometry

11:00 Coffee/tea break

• 11:30 Luiza Cardoso (Oroboros, Innsbruck, AT) O2k demo experiment: high-resolution respirometry and SUIT protocol with a mitochondrial preparation

13:00 Lunch

• 14:30 Short presentations by participants (S5-S8)
• 15:30 Luiza Cardoso (Oroboros, Innsbruck, AT) Respiration and H₂O₂ flux in brain mitochondria - tissue normoxia, hyperoxia and hypoxia

16:15 Coffee/tea break

• 16:45 Erich Gnaiger (Oroboros, Innsbruck, AT) MitObesity: Body fat excess, body mass excess and mitochondrial fitness - from muscle to brain
• 17:30 Final discussion - next steps